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9qiu

Crystal structure of YTHDF2 in complex with compound 13 (AI-DF2-56)

Method: X-RAY DIFFRACTION Dmax: 79.7 Å Quality: GOOD

SAXS Profile

SAXS profile for 9qiu

P(r) Distribution

P(r) distribution for 9qiu
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1. Structure Basics

entry_id9qiu
deposition_date2025-03-17
titleCrystal structure of YTHDF2 in complex with compound 13 (AI-DF2-56)
keywordsInhibitor, m6A reader, RNA BINDING PROTEIN; RNA BINDING PROTEIN
methodX-RAY DIFFRACTION
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Download Data

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2. SAXS Parameters (CRYSOL)

rg_guinier22.16 Å
rg_electron21.65 Å
i038471400.00
molecular_weight31530.0 kDa
excluded_volume30204 ų
envelope_volume50594 ų
shell_volume20146 ų
envelope_diameter80.5 Å
shell_rg27.62 Å
envelope_rg21.77 Å
shape_rg21.66 Å
total_rg22.21 Å
total_atoms2375
n_residues297
n_harmonics20
q_range— – 0.5000 Å−1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3
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3. P(r) Analysis (GNOM)

dmax79.7 Å
rg_real22.21 Å
rg_real_error0.71 Å
i0_real3.8470e+07
i0_real_error4.9010e+05
rg_reciprocal22.20 Å
i0_reciprocal38470000.0000
total_estimate0.8414
solution_quality GOOD a GOOD solution
n_peaks2
r_peak_primary23.8 Å
skewness0.426
kurtosis-0.253
angular_range— – 0.3600 Å−1
current_alpha0.0000
highest_alpha7036000.0000
n_real_points68
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.709; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.810; Smooth: 0.998
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4. Crystallography & Experiment

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5. Entities & Polymer Info (5)

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6. Citations (1)

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7. Files & Curves (10)