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9qj4

Structure of the Complement classical and lectin pathway proconvertase, C4b2

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Complement C4-A

OrganismNot specified

UniProt P0C0L4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 Complement C2 × 1 （P06681） 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 MAGNESIUM ION × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers
5jtw 5jtw

2 assemblies

Heteromeric or nucleic-acid complex
5jpm 5jpm 5jpn 6ysq 6ysq 7b2m 7b2p 7b2q 9qj4 9qj5 9qk2 9qpy

12 assemblies

View Construct and Data Evidence
UniProt name CO4A_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–1744； UniProt 1–1744 Author chain B； PDBConstruct 1–1744； UniProt 1–1744 Author chain C； PDBConstruct 1–1744； UniProt 1–1744

Complement C2

OrganismNot specified

UniProt P06681

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 Complement C4-A × 3 （P0C0L4） 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 MAGNESIUM ION × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
3erb

1 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2i6q 2i6s 2odp 2odq 8acf 8aci 9qj4 9qj5 9qk2 9qpy 9u5z 9u60

13 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name CO2_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain D； PDBConstruct 1–752； UniProt 1–752

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9qj4
Deposition date deposition_date2025-03-18
Structure title titleStructure of the Complement classical and lectin pathway proconvertase, C4b2
Keywords keywordsProconvertase, Complement, classical pathway, C4b2, IMMUNE SYSTEM; IMMUNE SYSTEM
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9qj4__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9qj4__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9qj4__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）43.75 Å
Rg (electron density)43.54 Å
Total Rg43.78 Å
Atom count15245
Residues1948
Excluded volume270610 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9qj4__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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7. Citations (1)