Crystal structure of hTEAD4 YAP binding domain (hTEAD4-YBD) in complex with peptide 6

entry_id	9qkq
deposition_date	2025-03-20
last_revision	2026-04-08
title	Crystal structure of hTEAD4 YAP binding domain (hTEAD4-YBD) in complex with peptide 6
keywords	human TEAD4, YAP binding domain, TRANSCRIPTION; TRANSCRIPTION
method	X-RAY DIFFRACTION

rg_guinier	26.14 Å
rg_electron	25.61 Å
i0	44137200.00
molecular_weight	53102.0 kDa
excluded_volume	66994 ų
envelope_volume	80769 ų
shell_volume	26853 ų
envelope_diameter	88.7 Å
shell_rg	32.39 Å
envelope_rg	25.57 Å
shape_rg	25.59 Å
total_rg	26.45 Å
total_atoms	3748
n_residues	444
n_harmonics	20
q_range	— – 0.5000 Å−1
n_points	101
shell_type	directional
solvent_density	0.3340 e/ų
contrast_shell	0.0300 e/ų
crysol_version	4.1.3

dmax	84.3 Å
rg_real	26.21 Å
rg_real_error	0.52 Å
i0_real	4.4140e+07
i0_real_error	5.9710e+05
rg_reciprocal	26.19 Å
i0_reciprocal	44140000.0000
total_estimate	0.8888
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	27.6 Å
skewness	0.431
kurtosis	-0.353
angular_range	— – 0.3050 Å−1
current_alpha	0.0000
highest_alpha	11180000.0000
n_real_points	62
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.877; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.976; Smooth: 0.944

Unit Cell

length_a	171.538 Å
length_b	40.243 Å
length_c	97.892 Å
angle_alpha	90.00 °
angle_beta	92.77 °
angle_gamma	90.00 °
z_pdb	8

Symmetry

space_group	C 1 2 1
int_tables_number	5
crystal_system	—

Refinement

resolution	1.740 Å
resolution_low	97.780 Å
r_factor	0.1850
r_work	0.1832
r_free	0.2210

Diffraction

temperature

100.0 K

Files (7)

• pr_distribution /app/data/pr_computation/qk/9qkq/pr_distribution.json
• pr_output /app/data/pr_computation/qk/9qkq/9qkq.pr.out
• pr_plot /app/data/visualization/pr_computation/qk/9qkq/9qkq_pr_distribution.png
• saxs_curve_dat /app/data/saxs_computation/qk/9qkq/9qkq.dat
• saxs_fit /app/data/saxs_computation/qk/9qkq/9qkq.fit
• saxs_log /app/data/saxs_computation/qk/9qkq/9qkq.log
• saxs_plot /app/data/visualization/saxs_computation/qk/9qkq/9qkq_saxs_profile.png

Curves (3)

fit	/app/data/saxs_computation/qk/9qkq/9qkq.fit
pddf	/app/data/pr_computation/qk/9qkq/9qkq.pr.out
profile	/app/data/saxs_computation/qk/9qkq/9qkq.dat