SAXSdb — 9r8z

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1. Structure Basics

entry_id	9r8z
deposition_date	2025-05-18
last_revision	2026-05-06
title	METTL3/14 complex with switchable fragment
keywords	Complex RNA modification, TRANSFERASE; TRANSFERASE
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	24.65 Å
rg_electron	24.06 Å
i0	101424000.00
molecular_weight	52823.0 kDa
excluded_volume	50979 Å³
envelope_volume	83550 Å³
shell_volume	28968 Å³
envelope_diameter	88.8 Å
shell_rg	31.21 Å
envelope_rg	24.28 Å
shape_rg	24.06 Å
total_rg	24.63 Å
total_atoms	3992
n_residues	488
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	96.5 Å
rg_real	24.65 Å
rg_real_error	1.14 Å
i0_real	1.0140e+08
i0_real_error	1.5770e+06
rg_reciprocal	24.65 Å
i0_reciprocal	101400000.0000
total_estimate	0.6979
solution_quality	REASONABLE a REASONABLE solution
n_peaks	3
r_peak_primary	26.0 Å
skewness	0.423
kurtosis	-0.110
angular_range	— – 0.3200 Å⁻¹
current_alpha	0.0000
highest_alpha	26620000.0000
n_real_points	64
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.450; Stabil: 0.993; Sysdev: 1.000; Positv: 1.000; Valcen: 0.742; Smooth: 0.000

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4. Crystallography & Experiment

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5. Entities & Polymer Info (6)

Entity 1 polymer

description	N(6)-adenosine-methyltransferase catalytic subunit METTL3
formula_weight	25604.4 kDa
ec_number	2.1.1.348
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	A
atom_count	4231

MSVGGDSSADRLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIPVLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVARFKQRYPDGIISKPKNL

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Escherichia coli

Entity 2 polymer

description	N(6)-adenosine-methyltransferase non-catalytic subunit METTL14
formula_weight	39516.6 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	B

GSQSLNPHNDYCQHFVDTGHRPQNFIRDVGLADRFEEYPKLRELIRLKDELIAKSNTPPMYLQADIEAFDIRELTPKFDVILLEPPLEEYYRETGITANEKCWTWDDIMKLEIDEIAAPRSFIFLWCGSGEGLDLGRVCLRKWGYRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTKEHCLMGIKGTVKRSTDGDFIHANVDIDLIITEEPEIGNIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPTLTNSNYNAETYASYFSAPNSYLTGCTEEIERLRPKSPPPKSKSDRGGGAPRGGGRGGTSAGRGRERNRSNFRGERGGFRGGRGGAHRGGFPPR

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Escherichia coli

Entity 3 non-polymer

description	DIMETHYL SULFOXIDE
formula_weight	78.1 kDa
src_method	syn
entity_count	5

Entity 4 non-polymer

description	1-(1~{H}-imidazol-2-yl)-2-phenyl-diazane
formula_weight	174.2 kDa
src_method	syn
entity_count	1

Entity 5 non-polymer

description	CHLORIDE ION
formula_weight	35.5 kDa
src_method	syn
entity_count	2

Entity 6 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	228

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6. Citations (1)

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length_a	100.830 Å
length_b	100.830 Å
length_c	117.700 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	8

space_group	P 41 21 2
int_tables_number	92
crystal_system	—

resolution	2.210 Å
resolution_low	76.570 Å
r_factor	—
r_work	0.1739
r_free	0.2271

fit	/app/data/saxs_computation/r8/9r8z/9r8z.fit
pddf	/app/data/pr_computation/r8/9r8z/9r8z.pr.out
profile	/app/data/saxs_computation/r8/9r8z/9r8z.dat

METTL3/14 complex with switchable fragment

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction

5. Entities & Polymer Info (6)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 non-polymer

Entity 4 non-polymer

Entity 5 non-polymer

Entity 6 water

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)