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9s46

Human SIRT2 in Complex with RW-78

Method: X-RAY DIFFRACTION Dmax: 68.4 Å Quality: REASONABLE

SAXS Profile

SAXS profile for 9s46

P(r) Distribution

P(r) distribution for 9s46

1. Structure Basics

entry_id9s46
deposition_date2025-07-25
titleHuman SIRT2 in Complex with RW-78
keywordsInhibitior, Lysine deacetylase, NAD+-dependant enzyme, Epigenetics, HYDROLASE; HYDROLASE
methodX-RAY DIFFRACTION

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier21.21
rg_electron20.38
i038246400.00
molecular_weight32165.0 kDa
excluded_volume31210 ų
envelope_volume51433 ų
shell_volume21284 ų
envelope_diameter70.9
shell_rg26.75
envelope_rg20.62
shape_rg20.35
total_rg21.08
total_atoms2422
n_residues298
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax68.4
rg_real21.17
rg_real_error0.36
i0_real3.8250e+07
i0_real_error4.6160e+05
rg_reciprocal21.18
i0_reciprocal38250000.0000
total_estimate0.7490
solution_quality REASONABLE a REASONABLE solution
n_peaks2
r_peak_primary24.1
skewness0.322
kurtosis-0.377
angular_range— – 0.3750 −1
current_alpha0.0000
highest_alpha6608000.0000
n_real_points69
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.882; Stabil: 1.000; Sysdev: 0.368; Positv: 1.000; Valcen: 0.997; Smooth: 0.988

4. Crystallography & Experiment

5. Entities & Polymer Info (5)

6. Citations (1)

7. Files & Curves (10)