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9s48

Human SIRT2 in Complex with RW-80

Method: X-RAY DIFFRACTION Dmax: 69.4 Å Quality: GOOD

SAXS Profile

SAXS profile for 9s48

P(r) Distribution

P(r) distribution for 9s48

1. Structure Basics

entry_id9s48
deposition_date2025-07-25
titleHuman SIRT2 in Complex with RW-80
keywordsInhibitior, Lysine deacetylase, NAD+-dependant enzyme, Epigenetics, HYDROLASE; HYDROLASE
methodX-RAY DIFFRACTION

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier21.01
rg_electron20.22
i037265500.00
molecular_weight31676.0 kDa
excluded_volume30670 ų
envelope_volume50436 ų
shell_volume21018 ų
envelope_diameter70.8
shell_rg26.66
envelope_rg20.53
shape_rg20.19
total_rg20.90
total_atoms2379
n_residues290
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax69.4
rg_real20.98
rg_real_error0.41
i0_real3.7270e+07
i0_real_error5.0790e+05
rg_reciprocal20.99
i0_reciprocal37270000.0000
total_estimate0.8862
solution_quality GOOD a GOOD solution
n_peaks2
r_peak_primary24.1
skewness0.339
kurtosis-0.351
angular_range— – 0.3800 −1
current_alpha0.0000
highest_alpha6404000.0000
n_real_points70
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.843; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.995; Smooth: 0.992

4. Crystallography & Experiment

5. Entities & Polymer Info (6)

6. Citations (1)

7. Files & Curves (10)