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9scx

The R90C clinical variant of human bisphosphoglycerate mutase (hBPGM).

Method: X-RAY DIFFRACTION D_max: 166.0 Å Quality: REASONABLE

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	9scx
deposition_date	2025-08-12
last_revision	2026-03-18
title	The R90C clinical variant of human bisphosphoglycerate mutase (hBPGM).
keywords	Human bisphosphoglycerate mutase (hBPGM)., ISOMERASE; ISOMERASE
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	45.03 Å
rg_electron	46.01 Å
i0	199786000.00
molecular_weight	115080.0 kDa
excluded_volume	143870 Å³
envelope_volume	189910 Å³
shell_volume	38865 Å³
envelope_diameter	165.2 Å
shell_rg	42.56 Å
envelope_rg	45.90 Å
shape_rg	46.01 Å
total_rg	45.83 Å
total_atoms	8134
n_residues	991
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	166.0 Å
rg_real	45.92 Å
rg_real_error	2.21 Å
i0_real	1.9980e+08
i0_real_error	3.9590e+06
rg_reciprocal	45.04 Å
i0_reciprocal	199600000.0000
total_estimate	0.6545
solution_quality	REASONABLE a REASONABLE solution
n_peaks	1
r_peak_primary	28.5 Å
skewness	0.608
kurtosis	-0.528
angular_range	— – 0.1750 Å⁻¹
current_alpha	0.0000
highest_alpha	21530000.0000
n_real_points	36
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.222; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.076; Smooth: 0.763

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4. Crystallography & Experiment

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5. Entities & Polymer Info (4)

Entity 1 polymer

description	Bisphosphoglycerate mutase
formula_weight	31064.3 kDa
ec_number	5.4.2.4,5.4.2.11
src_method	man
entity_count	4

Polymer

type	polypeptide(L)
strand_id	A,B,C,D
atom_count	8830

MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVLNRSIHTAWLILEELGQEWVPVESSWRLNECHYGALIGLNREQMALNHGEEQVRLWRRSYNVTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRGKTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAIQAAIKKVEDQGKVKQAKKLEHHHHHH

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Escherichia coli BL21(DE3)

Entity 2 non-polymer

description	GLYCEROL
formula_weight	92.1 kDa
src_method	syn
entity_count	4

Entity 3 non-polymer

description	1,2-ETHANEDIOL
formula_weight	62.1 kDa
src_method	syn
entity_count	1

Entity 4 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	211

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6. Citations (1)

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length_a	37.990 Å
length_b	47.781 Å
length_c	146.969 Å
angle_alpha	90.02 °
angle_beta	97.00 °
angle_gamma	95.34 °
z_pdb	4

space_group	P 1
int_tables_number	1
crystal_system	—

resolution	2.350 Å
resolution_low	45.380 Å
r_factor	0.2317
r_work	0.2292
r_free	0.2759

fit	/app/data/saxs_computation/sc/9scx/9scx.fit
pddf	/app/data/pr_computation/sc/9scx/9scx.pr.out
profile	/app/data/saxs_computation/sc/9scx/9scx.dat

The R90C clinical variant of human bisphosphoglycerate mutase (hBPGM).

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction