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9sd0

The Q102K clinical variant of human bisphosphoglycerate mutase (hBPGM).

Method: X-RAY DIFFRACTION D_max: 86.9 Å Quality: GOOD

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	9sd0
deposition_date	2025-08-12
last_revision	2026-03-18
title	The Q102K clinical variant of human bisphosphoglycerate mutase (hBPGM).
keywords	Human bisphosphoglycerate mutase (hBPGM)., ISOMERASE; ISOMERASE
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	25.93 Å
rg_electron	25.02 Å
i0	55876300.00
molecular_weight	58180.0 kDa
excluded_volume	72844 Å³
envelope_volume	86584 Å³
shell_volume	28961 Å³
envelope_diameter	88.8 Å
shell_rg	32.29 Å
envelope_rg	25.26 Å
shape_rg	25.02 Å
total_rg	25.82 Å
total_atoms	4105
n_residues	499
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	86.9 Å
rg_real	25.96 Å
rg_real_error	0.67 Å
i0_real	5.5880e+07
i0_real_error	6.7160e+05
rg_reciprocal	25.95 Å
i0_reciprocal	55880000.0000
total_estimate	0.8741
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	28.5 Å
skewness	0.413
kurtosis	-0.303
angular_range	— – 0.3050 Å⁻¹
current_alpha	0.0000
highest_alpha	21790000.0000
n_real_points	62
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.809; Stabil: 0.997; Sysdev: 1.000; Positv: 1.000; Valcen: 0.974; Smooth: 0.964

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4. Crystallography & Experiment

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5. Entities & Polymer Info (4)

Entity 1 polymer

description	Bisphosphoglycerate mutase
formula_weight	31119.4 kDa
ec_number	5.4.2.4,5.4.2.11
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	A,B
atom_count	4714

MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVLNRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREKMALNHGEEQVRLWRRSYNVTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRGKTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAIQAAIKKVEDQGKVKQAKKLEHHHHHH

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Escherichia coli BL21(DE3)

Entity 2 non-polymer

description	GLYCEROL
formula_weight	92.1 kDa
src_method	syn
entity_count	3

Entity 3 non-polymer

description	1,2-ETHANEDIOL
formula_weight	62.1 kDa
src_method	syn
entity_count	2

Entity 4 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	295

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6. Citations (1)

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length_a	37.992 Å
length_b	98.581 Å
length_c	131.395 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	8

space_group	P 2 21 21
int_tables_number	18
crystal_system	—

resolution	1.650 Å
resolution_low	65.700 Å
r_factor	0.1820
r_work	0.1806
r_free	0.2090

fit	/app/data/saxs_computation/sd/9sd0/9sd0.fit
pddf	/app/data/pr_computation/sd/9sd0/9sd0.pr.out
profile	/app/data/saxs_computation/sd/9sd0/9sd0.dat

The Q102K clinical variant of human bisphosphoglycerate mutase (hBPGM).

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction