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9sic

Crystal structure of human Signal Regulatory Protein 2 (SIRP) alpha V2 - Q52A mutant

Method: X-RAY DIFFRACTION Dmax: 80.1 Å Quality: EXCELLENT

SAXS Profile

SAXS profile for 9sic

P(r) Distribution

P(r) distribution for 9sic

1. Structure Basics

entry_id9sic
deposition_date2025-08-28
last_revision2026-01-28
titleCrystal structure of human Signal Regulatory Protein 2 (SIRP) alpha V2 - Q52A mutant
keywords;IMMUNOGLOBULIN SUPERFAMILY, SIRP, SIRPA, CD47, DON'T EAT ME SIGNAL, IMMUNE CHECKPOINT, IMMUNE SYSTEM ;; IMMUNE SYSTEM
methodX-RAY DIFFRACTION

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier26.77
rg_electron25.88
i024570600.00
molecular_weight37451.0 kDa
excluded_volume46548 ų
envelope_volume65181 ų
shell_volume21281 ų
envelope_diameter82.9
shell_rg32.78
envelope_rg25.09
shape_rg25.86
total_rg26.75
total_atoms2619
n_residues344
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax80.1
rg_real26.68
rg_real_error0.59
i0_real2.4570e+07
i0_real_error3.7130e+05
rg_reciprocal26.71
i0_reciprocal24570000.0000
total_estimate0.9032
solution_quality EXCELLENT a EXCELLENT solution
n_peaks3
r_peak_primary40.7
skewness0.048
kurtosis-0.806
angular_range— – 0.2950 −1
current_alpha0.0000
highest_alpha6889000.0000
n_real_points60
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.934; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.967; Smooth: 0.970

4. Crystallography & Experiment

5. Entities & Polymer Info (3)

6. Citations (1)

7. Files & Curves (10)