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9t7f

Crystal structure of human Signal Regulatory Protein 2 (SIRP) alpha V2 in complex with 5-Hydroxy-L-Tryptophan

Method: X-RAY DIFFRACTION Dmax: 81.1 Å Quality: EXCELLENT

SAXS Profile

SAXS profile for 9t7f

P(r) Distribution

P(r) distribution for 9t7f

1. Structure Basics

entry_id9t7f
deposition_date2025-11-10
last_revision2026-01-28
titleCrystal structure of human Signal Regulatory Protein 2 (SIRP) alpha V2 in complex with 5-Hydroxy-L-Tryptophan
keywords;IMMUNOGLOBULIN SUPERFAMILY, SIRP, SIRPA, DON'T EAT ME SIGNAL, IMMUNE CHECKPOINT, 5-HYDROX-TRYPTOPHAN, COMPLEX, IMMUNE SYSTEM ;; IMMUNE SYSTEM
methodX-RAY DIFFRACTION

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier26.70
rg_electron25.81
i024726600.00
molecular_weight37451.0 kDa
excluded_volume46486 ų
envelope_volume64196 ų
shell_volume21025 ų
envelope_diameter83.2
shell_rg32.67
envelope_rg25.12
shape_rg25.79
total_rg26.68
total_atoms2616
n_residues340
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax81.1
rg_real26.62
rg_real_error0.53
i0_real2.4730e+07
i0_real_error3.4220e+05
rg_reciprocal26.65
i0_reciprocal24730000.0000
total_estimate0.9011
solution_quality EXCELLENT a EXCELLENT solution
n_peaks3
r_peak_primary41.2
skewness0.052
kurtosis-0.796
angular_range— – 0.2950 −1
current_alpha0.0000
highest_alpha7249000.0000
n_real_points60
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.918; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.960; Smooth: 0.996

4. Crystallography & Experiment

5. Entities & Polymer Info (4)

6. Citations (1)

7. Files & Curves (10)