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9tnr

L12 G-quadruplex-forming aptamer targeting HMGB1 protein

Method: SOLUTION NMR Dmax: 33.8 Å Quality: GOOD

SAXS Profile

SAXS profile for 9tnr

P(r) Distribution

P(r) distribution for 9tnr

1. Structure Basics

entry_id9tnr
deposition_date2025-12-16
last_revision2026-04-08
titleL12 G-quadruplex-forming aptamer targeting HMGB1 protein
keywordsaptamer, HMGB1, G-quadruplex, DNA; DNA
methodSOLUTION NMR

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier10.99
rg_electron10.83
i0273485000.00
molecular_weight82165.0 kDa
excluded_volume79055 ų
envelope_volume12702 ų
shell_volume9431 ų
envelope_diameter35.6
shell_rg17.06
envelope_rg11.79
shape_rg10.59
total_rg11.33
total_atoms8430
n_residues260
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax33.8
rg_real10.91
rg_real_error0.15
i0_real2.7350e+08
i0_real_error2.5020e+06
rg_reciprocal10.91
i0_reciprocal273500000.0000
total_estimate0.8952
solution_quality GOOD a GOOD solution
n_peaks2
r_peak_primary13.2
skewness0.117
kurtosis-0.416
angular_range— – 0.5000 −1
current_alpha0.0000
highest_alpha683500.0000
n_real_points80
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.897; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.983; Smooth: 0.960

4. Crystallography & Experiment

5. Entities & Polymer Info (1)

6. Citations (1)

7. Files & Curves (10)