9tqb

Octameric C. elegans BORC, containing BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and the shared BORC and BLoC-1 subunits, BLOC1S1, BLOC1S2 and Snapin

Method: ELECTRON MICROSCOPY

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Biogenesis of lysosome-related organelles complex 1 subunit 1

Caenorhabditis elegans

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 8	Biogenesis of lysosome-related organelles complex 1 subunit 2 × 1 （Q95XD3） SNAPIN protein homolog × 1 （O44445） KxDL domain-containing protein × 1 （O01488） BLOC-1-related complex subunit 5 × 1 （O01902） BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein × 1 （Q9TYN4） BLOC-1-related complex subunit 7 × 1 （Q21655） BLOC-1-related complex subunit 8 homolog × 1 （O45685）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	BL1S1_CAEEL
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain G； PDBConstruct 1–129； UniProt 1–129

Biogenesis of lysosome-related organelles complex 1 subunit 2

Caenorhabditis elegans

UniProt Q95XD3

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 8	Biogenesis of lysosome-related organelles complex 1 subunit 1 × 1 （Q22616） SNAPIN protein homolog × 1 （O44445） KxDL domain-containing protein × 1 （O01488） BLOC-1-related complex subunit 5 × 1 （O01902） BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein × 1 （Q9TYN4） BLOC-1-related complex subunit 7 × 1 （Q21655） BLOC-1-related complex subunit 8 homolog × 1 （O45685）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	BL1S2_CAEEL
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain H； PDBConstruct 1–132； UniProt 1–132

SNAPIN protein homolog

Caenorhabditis elegans

UniProt O44445

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 8	Biogenesis of lysosome-related organelles complex 1 subunit 1 × 1 （Q22616） Biogenesis of lysosome-related organelles complex 1 subunit 2 × 1 （Q95XD3） KxDL domain-containing protein × 1 （O01488） BLOC-1-related complex subunit 5 × 1 （O01902） BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein × 1 （Q9TYN4） BLOC-1-related complex subunit 7 × 1 （Q21655） BLOC-1-related complex subunit 8 homolog × 1 （O45685）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	SNAPN_CAEEL
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain F； PDBConstruct 1–122； UniProt 1–122

KxDL domain-containing protein

Caenorhabditis

UniProt O01488

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 8	Biogenesis of lysosome-related organelles complex 1 subunit 1 × 1 （Q22616） Biogenesis of lysosome-related organelles complex 1 subunit 2 × 1 （Q95XD3） SNAPIN protein homolog × 1 （O44445） BLOC-1-related complex subunit 5 × 1 （O01902） BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein × 1 （Q9TYN4） BLOC-1-related complex subunit 7 × 1 （Q21655） BLOC-1-related complex subunit 8 homolog × 1 （O45685）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	O01488_CAEEL
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain E； PDBConstruct 1–140； UniProt 1–140

BLOC-1-related complex subunit 5

Caenorhabditis elegans

UniProt O01902

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 8	Biogenesis of lysosome-related organelles complex 1 subunit 1 × 1 （Q22616） Biogenesis of lysosome-related organelles complex 1 subunit 2 × 1 （Q95XD3） SNAPIN protein homolog × 1 （O44445） KxDL domain-containing protein × 1 （O01488） BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein × 1 （Q9TYN4） BLOC-1-related complex subunit 7 × 1 （Q21655） BLOC-1-related complex subunit 8 homolog × 1 （O45685）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	O01902_CAEEL
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain A； PDBConstruct 1–240； UniProt 1–240

BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein

Caenorhabditis elegans

UniProt Q9TYN4

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 8	Biogenesis of lysosome-related organelles complex 1 subunit 1 × 1 （Q22616） Biogenesis of lysosome-related organelles complex 1 subunit 2 × 1 （Q95XD3） SNAPIN protein homolog × 1 （O44445） KxDL domain-containing protein × 1 （O01488） BLOC-1-related complex subunit 5 × 1 （O01902） BLOC-1-related complex subunit 7 × 1 （Q21655） BLOC-1-related complex subunit 8 homolog × 1 （O45685）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q9TYN4_CAEEL
Isoform	—
PDB entities	6
Chains and sequence ranges	Author chain B； PDBConstruct 1–157； UniProt 1–157

BLOC-1-related complex subunit 7

Caenorhabditis elegans

UniProt Q21655

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 8	Biogenesis of lysosome-related organelles complex 1 subunit 1 × 1 （Q22616） Biogenesis of lysosome-related organelles complex 1 subunit 2 × 1 （Q95XD3） SNAPIN protein homolog × 1 （O44445） KxDL domain-containing protein × 1 （O01488） BLOC-1-related complex subunit 5 × 1 （O01902） BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein × 1 （Q9TYN4） BLOC-1-related complex subunit 8 homolog × 1 （O45685）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q21655_CAEEL
Isoform	—
PDB entities	7
Chains and sequence ranges	Author chain C； PDBConstruct 1–126； UniProt 1–126

BLOC-1-related complex subunit 8 homolog

Caenorhabditis elegans

UniProt O45685

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 8	Biogenesis of lysosome-related organelles complex 1 subunit 1 × 1 （Q22616） Biogenesis of lysosome-related organelles complex 1 subunit 2 × 1 （Q95XD3） SNAPIN protein homolog × 1 （O44445） KxDL domain-containing protein × 1 （O01488） BLOC-1-related complex subunit 5 × 1 （O01902） BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein × 1 （Q9TYN4） BLOC-1-related complex subunit 7 × 1 （Q21655）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	BORC8_CAEEL
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain D； PDBConstruct 1–151； UniProt 1–151

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	9tqb
Deposition date deposition_date	2025-12-19
Structure title title	Octameric C. elegans BORC, containing BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and the shared BORC and BLoC-1 subunits, BLOC1S1, BLOC1S2 and Snapin
Keywords keywords	BORC, BLOC-1, lysosome, recycling endosome, EARP, TRANSPORT PROTEIN; TRANSPORT PROTEIN
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9tqb__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9tqb__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

9tqb__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	63.35 Å
Rg (electron density)	67.48 Å
Total Rg	66.20 Å
Atom count	11843
Residues	749
Excluded volume	104690 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`9tqb__assembly_1__model_1`	octameric （8）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (8)

Entity 1 Entity 1 polymer

Description description	Biogenesis of lysosome-related organelles complex 1 subunit 1
Molecular weight formula_weight	14698.6 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	G
Atom count atom_count	11843

MLKEHSKKQHLRREVQEKLKNEAIVAAQTLSTAVVDHLNAKVAQAYGNQKRLDVEAKRFENNSAALAKQTEQWLFITEGLNYALKEIGDVENWSKTIENDMKIITETLRRAYEAKNPPLPPNQANPASH

Source Source

Source organism organism	Caenorhabditis elegans
NCBI taxonomy ID ncbi_taxonomy_id	6239
Host organism host_organism	Escherichia coli

Entity 2 Entity 2 polymer

Description description	Biogenesis of lysosome-related organelles complex 1 subunit 2
Molecular weight formula_weight	15013.7 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	H

MAEINERASTSSPPVPSTPAPVPHIRQLADNMTDKVGQFFQHQLEGSIEEYKLLETMNNTTAQRYVDMKVVAEKVAGKLDNLNQKYENLRPYLSQIDAMDESTRRLEEATAVLENYVTQLESKLTNIQQQSQ

Source Source

Source organism organism	Caenorhabditis elegans
NCBI taxonomy ID ncbi_taxonomy_id	6239
Host organism host_organism	Escherichia coli

Entity 3 Entity 3 polymer

Description description	SNAPIN protein homolog
Molecular weight formula_weight	13837.6 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	F

MSSTAGGEVSINSGDLLLGTLSTSITKLEQQIRATQLSQKKLNSDCETMAEYLRDLSEYKQPVDLLPYVGKLNDSTIRVNNTHQKLDDLLERLTKLQRQIARETYKKKNSIKEQEPPVQPEN

Source Source

Source organism organism	Caenorhabditis elegans
NCBI taxonomy ID ncbi_taxonomy_id	6239
Host organism host_organism	Escherichia coli

Entity 4 Entity 4 polymer

Description description	KxDL domain-containing protein
Molecular weight formula_weight	16295.4 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	E

MAEKNHQQQERLPGNPFFPSRSNAGSSFDMPETPHLIDSLTSQIDEFTIQSIIDTQRQSLKRFEKTNEMLMNCAQLGDRRIEKAKRDSVGHKETILQMKTDLEFIFKKIRMFKTVLSSKYPEVYAEVSAELTPKRSEEDE

Source Source

Source organism organism	Caenorhabditis
NCBI taxonomy ID ncbi_taxonomy_id	6237
Host organism host_organism	Escherichia coli

Entity 5 Entity 5 polymer

Description description	BLOC-1-related complex subunit 5
Molecular weight formula_weight	26732.2 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A

MANEQSSSTAGTSSNPQNQQSSFSFLTRASTKRSKGIITVKDGNIPQEKLEDDEIYKRFTEIPRFLPVIPAVIGKRDPQTNQGASYTHQKISSRPFFRLATRLQEHFAVNAKAVAADQAKIPATCKSVEAKMIRLIEETRAHKEQHDGFMAALSGLNQLHEDICSIQIILEDIVPMVETLNEILTPDERLPPLNLGSVLDRSPVPSSDSSLQSTPRHNQNIGHIDQIEPIEEIRVVDLPK

Source Source

Source organism organism	Caenorhabditis elegans
NCBI taxonomy ID ncbi_taxonomy_id	6239
Host organism host_organism	Escherichia coli

Entity 6 Entity 6 polymer

Description description	BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein
Molecular weight formula_weight	18177.5 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B

MSTSTESPDTPTTSQPLLSNKQTSFVVDDLEERIRESARISSPKRAAAAGLPDPKILVDLETHTKEIVNNMDTMLRDMRGSLHGMSDLTLESLQCYNSGVEKACDEADANVKSTYAMLAKVEEVNQSMGNVQKLAGQIKEMRRLVELFETLFHGSLKENLYFQ

Source Source

Source organism organism	Caenorhabditis elegans
NCBI taxonomy ID ncbi_taxonomy_id	6239
Host organism host_organism	Escherichia coli

Entity 7 Entity 7 polymer

Description description	BLOC-1-related complex subunit 7
Molecular weight formula_weight	13864.5 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C

MSISLESKTKLPQKILEIITDGSALLSIPMSSSQASETLLTSAKQFSHVEQVIDNTDKLLREIEQMVDGVTKNAEDMEKGLDIVCDVQECLQKVERQNYYSAVPKSFSADSFSSSVAGERPNPPNN

Source Source

Source organism organism	Caenorhabditis elegans
NCBI taxonomy ID ncbi_taxonomy_id	6239
Host organism host_organism	Escherichia coli

Entity 8 Entity 8 polymer

Description description	BLOC-1-related complex subunit 8 homolog
Molecular weight formula_weight	16878.8 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	D

MPDPSSTPNRTREIESRSRIISERICESVRLLDNEPSLALYRLQEHTVRSLPGLVNRRIMLTQQSATLSGAQFDLENTLSTTTSMQNATSAFDNCIELLRNCMFYKQQLDFDSTRKATSSAESSTVKGRSKSLHNVATRVHSTEASTSNDA

Source Source

Source organism organism	Caenorhabditis elegans
NCBI taxonomy ID ncbi_taxonomy_id	6239
Host organism host_organism	Escherichia coli

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Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	triclinic

Resolution resolution	7.80 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	201956

Octameric C. elegans BORC, containing BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and the shared BORC and BLoC-1 subunits, BLOC1S1, BLOC1S2 and Snapin

1. Protein Identity and Related Structures Protein Identity & Related Structures

Biogenesis of lysosome-related organelles complex 1 subunit 1

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Biogenesis of lysosome-related organelles complex 1 subunit 2

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

SNAPIN protein homolog

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

KxDL domain-containing protein

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

BLOC-1-related complex subunit 5

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

BLOC-1-related complex subunit 7

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

BLOC-1-related complex subunit 8 homolog

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

9tqb__assembly_1__model_1

9tqb__assembly_1__model_1 | I(q)

9tqb__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (8)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer