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9ujq

Cryo-EM structure of HQY1027-bound alpha-synuclein fibril polymorph 6A6B

Method: ELECTRON MICROSCOPY Dmax: 111.2 Å Quality: GOOD

SAXS Profile

SAXS profile for 9ujq

P(r) Distribution

P(r) distribution for 9ujq

1. Structure Basics

entry_id9ujq
deposition_date2025-04-17
titleCryo-EM structure of HQY1027-bound alpha-synuclein fibril polymorph 6A6B
keywordsamyloid fibril, complex, PROTEIN FIBRIL; PROTEIN FIBRIL
methodELECTRON MICROSCOPY

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier28.42
rg_electron28.58
i022903300.00
molecular_weight37369.0 kDa
excluded_volume47285 ų
envelope_volume62227 ų
shell_volume20119 ų
envelope_diameter113.6
shell_rg32.13
envelope_rg29.02
shape_rg28.60
total_rg28.95
total_atoms2628
n_residues378
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax111.2
rg_real28.72
rg_real_error1.36
i0_real2.2900e+07
i0_real_error4.1420e+05
rg_reciprocal28.63
i0_reciprocal22900000.0000
total_estimate0.7988
solution_quality GOOD a GOOD solution
n_peaks1
r_peak_primary27.8
skewness0.495
kurtosis-0.121
angular_range— – 0.2800 −1
current_alpha0.0000
highest_alpha1274000.0000
n_real_points57
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.646; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.447; Smooth: 0.996

4. Crystallography & Experiment

5. Entities & Polymer Info (1)

6. Citations (1)

7. Files & Curves (10)