9ulz
Cryo-EM structure of hIAPP fibrils extracted from a donor with T2D and pancreatic cancer
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 9ulz |
| deposition_date | 2025-04-21 |
| title | Cryo-EM structure of hIAPP fibrils extracted from a donor with T2D and pancreatic cancer |
| keywords | Amyloid fibrils, type II diabetes, hIAPP, PROTEIN FIBRIL; PROTEIN FIBRIL |
| method | ELECTRON MICROSCOPY |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 24.41 Å |
| rg_electron | 23.32 Å |
| i0 | 41367800.00 |
| molecular_weight | 45350.0 kDa |
| excluded_volume | 54892 ų |
| envelope_volume | 66684 ų |
| shell_volume | 24719 ų |
| envelope_diameter | 87.2 Å |
| shell_rg | 29.59 Å |
| envelope_rg | 23.61 Å |
| shape_rg | 23.15 Å |
| total_rg | 24.45 Å |
| total_atoms | 3168 |
| n_residues | 432 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 85.8 Å |
| rg_real | 24.54 Å |
| rg_real_error | 0.77 Å |
| i0_real | 4.1370e+07 |
| i0_real_error | 5.7170e+05 |
| rg_reciprocal | 24.51 Å |
| i0_reciprocal | 41370000.0000 |
| total_estimate | 0.8438 |
| solution_quality | GOOD a GOOD solution |
| n_peaks | 2 |
| r_peak_primary | 25.9 Å |
| skewness | 0.533 |
| kurtosis | 0.012 |
| angular_range | — – 0.3250 Å−1 |
| current_alpha | 0.0000 |
| highest_alpha | 3944000.0000 |
| n_real_points | 64 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.000; Oscil: 0.699; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.875; Smooth: 0.994 |