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9uys

Tyrosine-protein phosphatase non-receptor type 2

Method: X-RAY DIFFRACTION D_max: 88.8 Å Quality: GOOD

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	9uys
deposition_date	2025-05-15
last_revision	2026-05-27
title	Tyrosine-protein phosphatase non-receptor type 2
keywords	COMPLEX, HYDROLASE; HYDROLASE
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	27.41 Å
rg_electron	26.83 Å
i0	142266000.00
molecular_weight	62830.0 kDa
excluded_volume	60588 Å³
envelope_volume	100540 Å³
shell_volume	31220 Å³
envelope_diameter	95.9 Å
shell_rg	34.01 Å
envelope_rg	26.75 Å
shape_rg	26.81 Å
total_rg	27.38 Å
total_atoms	4752
n_residues	578
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	88.8 Å
rg_real	27.39 Å
rg_real_error	0.52 Å
i0_real	1.4230e+08
i0_real_error	2.1790e+06
rg_reciprocal	27.40 Å
i0_reciprocal	142300000.0000
total_estimate	0.8993
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	29.1 Å
skewness	0.292
kurtosis	-0.519
angular_range	— – 0.2900 Å⁻¹
current_alpha	0.0000
highest_alpha	24840000.0000
n_real_points	59
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.905; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.993; Smooth: 0.980

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4. Crystallography & Experiment

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5. Entities & Polymer Info (3)

Entity 1 polymer

description	Tyrosine-protein phosphatase non-receptor type 2
formula_weight	34989.6 kDa
ec_number	3.1.3.48
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	A,B
atom_count	4961

GPLGSPWGSIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKED

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Escherichia coli

Entity 2 non-polymer

description	5-[3-fluoranyl-5-oxidanyl-4-[1,1,4-tris(oxidanylidene)-1,2,5-thiadiazolidin-2-yl]phenyl]-~{N}-(3-methylbutyl)furan-2-carboxamide
formula_weight	425.4 kDa
src_method	syn
entity_count	2

Entity 3 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	209

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6. Citations (1)

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length_a	58.290 Å
length_b	76.980 Å
length_c	78.330 Å
angle_alpha	90.00 °
angle_beta	111.28 °
angle_gamma	90.00 °
z_pdb	4

space_group	P 1 21 1
int_tables_number	4
crystal_system	monoclinic

resolution	2.040 Å
resolution_low	44.380 Å
r_factor	0.1917
r_work	0.1899
r_free	0.2253

fit	/app/data/saxs_computation/uy/9uys/9uys.fit
pddf	/app/data/pr_computation/uy/9uys/9uys.pr.out
profile	/app/data/saxs_computation/uy/9uys/9uys.dat

Tyrosine-protein phosphatase non-receptor type 2

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction