SAXSdb — 9v2o

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1. Structure Basics

entry_id	9v2o
deposition_date	2025-05-20
title	Cryo-EM structure of RSV pre-F monomer in complex with CNR2056/CNR2047
keywords	RSV, Fusion Protein, Antibody, VIRAL PROTEIN; VIRAL PROTEIN
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	38.91 Å
rg_electron	38.99 Å
i0	153849000.00
molecular_weight	99921.0 kDa
excluded_volume	124930 Å³
envelope_volume	166370 Å³
shell_volume	38335 Å³
envelope_diameter	147.7 Å
shell_rg	41.03 Å
envelope_rg	39.04 Å
shape_rg	38.99 Å
total_rg	39.15 Å
total_atoms	7020
n_residues	916
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	137.8 Å
rg_real	39.24 Å
rg_real_error	1.55 Å
i0_real	1.5380e+08
i0_real_error	3.2130e+06
rg_reciprocal	39.04 Å
i0_reciprocal	153800000.0000
total_estimate	0.8444
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	33.6 Å
skewness	0.425
kurtosis	-0.457
angular_range	— – 0.2050 Å⁻¹
current_alpha	0.0000
highest_alpha	17360000.0000
n_real_points	42
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.772; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.732; Smooth: 0.925

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4. Crystallography & Experiment

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5. Entities & Polymer Info (5)

Entity 1 polymer

description	CNR2056 heavy chain
formula_weight	13949.5 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	A
atom_count	7020

QVQLVESGGGVVQPGTSLTLSCAASGFTFRTYAFHWVRQAPGKGLEWLALVTYDGTTQYYADSVKGRLTIYRDNSKNTLFLHLNSLRRDDTAIYFCARGGEGSFSWLGYLQYMDVWGQGTTVTVSS

Source

organism	Homo sapiens
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

Entity 2 polymer

description	RSV Pre-fusion Protein
formula_weight	61626.5 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	B

MELLILKANAITTILTAVTFCFASGQNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKENKCNGTDAKVKLIKQELDKYKNAVTELQLLMQSTPATNNRARRELPRFMNYTLNNAKKTNVTLSKKRKRRFLGFLLGVGSAIASGVAVCKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTFKVLDLKNYIDKQLLPILNKQSCSISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMCIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFIRKSDELLSAIGGYIPEAPRDGQAYVRKDGEWVLLSTFLGHHHHHHHH

Source

organism	Respiratory syncytial virus A2
ncbi_taxonomy_id	1972429
host_organism	Homo sapiens

Entity 3 polymer

description	CNR2056 light chain
formula_weight	11619.6 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	C

QSALTQPASVSGSPGQSITLSCTGTSSDIGDYDYVSWYQKYPDTAPKLVIYDVSERPSGVSTRFSGSKSGNTASLTISGLQPEDEADYYCNSYSSTNTLKFGGGTKLTVL

Source

organism	Homo sapiens
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

Entity 4 polymer

description	CNR2047 heavy chain
formula_weight	12947.6 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	D

VQLVESGGGLVKPGESLRLSCAVSGSMFSSYVMHWVRQAPGKGLDWVSSITGGGNYISYADSVKGRFIISRDNGRNSLSLQMSSLRVDDTAVYYCVRGLSGVMGVTWFDSWGQGTLVTVSS

Source

organism	Homo sapiens
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

Entity 5 polymer

description	CNR2047 light chain
formula_weight	11717.9 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	E

QSVLTQPPSVSGAPGQRVTISCTGSSSNIGAGFDVHWYQHLPGKAPKVIIYENSHRPSGVPDRFFGSKSGTSASLSISGLQPEDEADYYCQSYDRGLDWVFGGGTKLTVL

Source

organism	Homo sapiens
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

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6. Citations (1)

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resolution	4.270 Å
resolution_low	— Å
r_factor	—
r_work	—
r_free	—

resolution	4.27 Å
resolution_method	—
num_particles	62532

fit	/app/data/saxs_computation/v2/9v2o/9v2o.fit
pddf	/app/data/pr_computation/v2/9v2o/9v2o.pr.out
profile	/app/data/saxs_computation/v2/9v2o/9v2o.dat

Cryo-EM structure of RSV pre-F monomer in complex with CNR2056/CNR2047

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Refinement

EM 3D

5. Entities & Polymer Info (5)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 polymer

Polymer

Source

Entity 4 polymer

Polymer

Source

Entity 5 polymer

Polymer

Source

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)