SAXSdb — 9v2q

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1. Structure Basics

entry_id	9v2q
deposition_date	2025-05-20
title	Cryo-EM structure of RSV pre-F dimer in complex with CNR2056/CNR2047
keywords	RSV, Fusion Protein, Antibody, VIRAL PROTEIN; VIRAL PROTEIN
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	47.99 Å
rg_electron	47.31 Å
i0	584239000.00
molecular_weight	199840.0 kDa
excluded_volume	249860 Å³
envelope_volume	370580 Å³
shell_volume	64292 Å³
envelope_diameter	155.3 Å
shell_rg	53.13 Å
envelope_rg	45.68 Å
shape_rg	47.30 Å
total_rg	47.57 Å
total_atoms	14040
n_residues	1832
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	146.5 Å
rg_real	47.72 Å
rg_real_error	1.29 Å
i0_real	5.8420e+08
i0_real_error	1.1600e+07
rg_reciprocal	47.98 Å
i0_reciprocal	584400000.0000
total_estimate	0.8995
solution_quality	GOOD a GOOD solution
n_peaks	1
r_peak_primary	71.0 Å
skewness	-0.020
kurtosis	-0.757
angular_range	— – 0.1650 Å⁻¹
current_alpha	0.0000
highest_alpha	33630000.0000
n_real_points	34
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.947; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.999; Smooth: 0.850

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4. Crystallography & Experiment

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5. Entities & Polymer Info (5)

Entity 1 polymer

description	CNR2056 heavy chain
formula_weight	13949.5 kDa
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	A,F
atom_count	14040

QVQLVESGGGVVQPGTSLTLSCAASGFTFRTYAFHWVRQAPGKGLEWLALVTYDGTTQYYADSVKGRLTIYRDNSKNTLFLHLNSLRRDDTAIYFCARGGEGSFSWLGYLQYMDVWGQGTTVTVSS

Source

organism	Homo sapiens
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

Entity 2 polymer

description	RSV Pre-fusion Protein
formula_weight	61626.5 kDa
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	B,G

MELLILKANAITTILTAVTFCFASGQNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKENKCNGTDAKVKLIKQELDKYKNAVTELQLLMQSTPATNNRARRELPRFMNYTLNNAKKTNVTLSKKRKRRFLGFLLGVGSAIASGVAVCKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTFKVLDLKNYIDKQLLPILNKQSCSISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMCIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFIRKSDELLSAIGGYIPEAPRDGQAYVRKDGEWVLLSTFLGHHHHHHHH

Source

organism	Respiratory syncytial virus A2
ncbi_taxonomy_id	1972429
host_organism	Homo sapiens

Entity 3 polymer

description	CNR2056 light chain
formula_weight	11619.6 kDa
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	C,H

QSALTQPASVSGSPGQSITLSCTGTSSDIGDYDYVSWYQKYPDTAPKLVIYDVSERPSGVSTRFSGSKSGNTASLTISGLQPEDEADYYCNSYSSTNTLKFGGGTKLTVL

Source

organism	Homo sapiens
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

Entity 4 polymer

description	CNR2047 heavy chain
formula_weight	12947.6 kDa
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	D,I

VQLVESGGGLVKPGESLRLSCAVSGSMFSSYVMHWVRQAPGKGLDWVSSITGGGNYISYADSVKGRFIISRDNGRNSLSLQMSSLRVDDTAVYYCVRGLSGVMGVTWFDSWGQGTLVTVSS

Source

organism	Homo sapiens
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

Entity 5 polymer

description	CNR2047 light chain
formula_weight	11717.9 kDa
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	E,J

QSVLTQPPSVSGAPGQRVTISCTGSSSNIGAGFDVHWYQHLPGKAPKVIIYENSHRPSGVPDRFFGSKSGTSASLSISGLQPEDEADYYCQSYDRGLDWVFGGGTKLTVL

Source

organism	Homo sapiens
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

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6. Citations (1)

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resolution	4.430 Å
resolution_low	— Å
r_factor	—
r_work	—
r_free	—

resolution	4.43 Å
resolution_method	—
num_particles	44987

fit	/app/data/saxs_computation/v2/9v2q/9v2q.fit
pddf	/app/data/pr_computation/v2/9v2q/9v2q.pr.out
profile	/app/data/saxs_computation/v2/9v2q/9v2q.dat

Cryo-EM structure of RSV pre-F dimer in complex with CNR2056/CNR2047

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Refinement

EM 3D

5. Entities & Polymer Info (5)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 polymer

Polymer

Source

Entity 4 polymer

Polymer

Source

Entity 5 polymer

Polymer

Source

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)