SAXSdb — 9v2r

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1. Structure Basics

entry_id	9v2r
deposition_date	2025-05-20
title	Cryo-EM structure of RSV pre-F trimer in complex with CNR2056/CNR2047
keywords	RSV, Fusion Protein, Antibody, VIRAL PROTEIN; VIRAL PROTEIN
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	46.08 Å
rg_electron	45.42 Å
i0	1312460000.00
molecular_weight	299760.0 kDa
excluded_volume	374800 Å³
envelope_volume	493020 Å³
shell_volume	88321 Å³
envelope_diameter	152.2 Å
shell_rg	51.54 Å
envelope_rg	45.00 Å
shape_rg	45.44 Å
total_rg	45.59 Å
total_atoms	21060
n_residues	2748
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	146.5 Å
rg_real	45.78 Å
rg_real_error	0.99 Å
i0_real	1.3120e+09
i0_real_error	2.2330e+07
rg_reciprocal	46.07 Å
i0_reciprocal	1313000000.0000
total_estimate	0.8799
solution_quality	GOOD a GOOD solution
n_peaks	1
r_peak_primary	60.3 Å
skewness	0.110
kurtosis	-0.408
angular_range	— – 0.1700 Å⁻¹
current_alpha	0.0000
highest_alpha	116700000.0000
n_real_points	35
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.862; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.961; Smooth: 0.888

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4. Crystallography & Experiment

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5. Entities & Polymer Info (5)

Entity 1 polymer

description	CNR2056 heavy chain
formula_weight	13949.5 kDa
src_method	man
entity_count	3

Polymer

type	polypeptide(L)
strand_id	A,F,G
atom_count	21060

QVQLVESGGGVVQPGTSLTLSCAASGFTFRTYAFHWVRQAPGKGLEWLALVTYDGTTQYYADSVKGRLTIYRDNSKNTLFLHLNSLRRDDTAIYFCARGGEGSFSWLGYLQYMDVWGQGTTVTVSS

Source

organism	Homo sapiens
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

Entity 2 polymer

description	RSV Pre-fusion Protein
formula_weight	61626.5 kDa
src_method	man
entity_count	3

Polymer

type	polypeptide(L)
strand_id	B,H,I

MELLILKANAITTILTAVTFCFASGQNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKENKCNGTDAKVKLIKQELDKYKNAVTELQLLMQSTPATNNRARRELPRFMNYTLNNAKKTNVTLSKKRKRRFLGFLLGVGSAIASGVAVCKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTFKVLDLKNYIDKQLLPILNKQSCSISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMCIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFIRKSDELLSAIGGYIPEAPRDGQAYVRKDGEWVLLSTFLGHHHHHHHH

Source

organism	Respiratory syncytial virus A2
ncbi_taxonomy_id	1972429
host_organism	Homo sapiens

Entity 3 polymer

description	CNR2056 light chain
formula_weight	11619.6 kDa
src_method	man
entity_count	3

Polymer

type	polypeptide(L)
strand_id	C,J,K

QSALTQPASVSGSPGQSITLSCTGTSSDIGDYDYVSWYQKYPDTAPKLVIYDVSERPSGVSTRFSGSKSGNTASLTISGLQPEDEADYYCNSYSSTNTLKFGGGTKLTVL

Source

organism	Homo sapiens
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

Entity 4 polymer

description	CNR2047 heavy chain
formula_weight	12947.6 kDa
src_method	man
entity_count	3

Polymer

type	polypeptide(L)
strand_id	D,L,M

VQLVESGGGLVKPGESLRLSCAVSGSMFSSYVMHWVRQAPGKGLDWVSSITGGGNYISYADSVKGRFIISRDNGRNSLSLQMSSLRVDDTAVYYCVRGLSGVMGVTWFDSWGQGTLVTVSS

Source

organism	Homo sapiens
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

Entity 5 polymer

description	CNR2047 light chain
formula_weight	11717.9 kDa
src_method	man
entity_count	3

Polymer

type	polypeptide(L)
strand_id	E,N,O

QSVLTQPPSVSGAPGQRVTISCTGSSSNIGAGFDVHWYQHLPGKAPKVIIYENSHRPSGVPDRFFGSKSGTSASLSISGLQPEDEADYYCQSYDRGLDWVFGGGTKLTVL

Source

organism	Homo sapiens
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

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6. Citations (1)

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resolution	4.400 Å
resolution_low	— Å
r_factor	—
r_work	—
r_free	—

resolution	4.40 Å
resolution_method	—
num_particles	12437

fit	/app/data/saxs_computation/v2/9v2r/9v2r.fit
pddf	/app/data/pr_computation/v2/9v2r/9v2r.pr.out
profile	/app/data/saxs_computation/v2/9v2r/9v2r.dat

Cryo-EM structure of RSV pre-F trimer in complex with CNR2056/CNR2047

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Refinement

EM 3D

5. Entities & Polymer Info (5)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 polymer

Polymer

Source

Entity 4 polymer

Polymer

Source

Entity 5 polymer

Polymer

Source

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)