SAXSdb — 9yya

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Macrophage migration inhibitory factor

Necator americanus

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 3	water × 3	Consistent with protein count
2	Protein homooligomer	Homooligomer	Protein 3	water × 3	Consistent with protein count
3	Protein homooligomer	Homooligomer	Protein 3	water × 3	Consistent with protein count
4	Protein homooligomer	Homooligomer	Protein 3	water × 3	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	W2TWH5_NECAM
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–118； UniProt 2–119 Author chain B； PDBConstruct 1–118； UniProt 2–119 Author chain C； PDBConstruct 1–118； UniProt 2–119 Author chain D； PDBConstruct 1–118； UniProt 2–119 Author chain E； PDBConstruct 1–118； UniProt 2–119 Author chain F； PDBConstruct 1–118； UniProt 2–119 Author chain G； PDBConstruct 1–118； UniProt 2–119 Author chain H； PDBConstruct 1–118； UniProt 2–119 Author chain I； PDBConstruct 1–118； UniProt 2–119 Author chain J； PDBConstruct 1–118； UniProt 2–119 Author chain K； PDBConstruct 1–118； UniProt 2–119 Author chain L； PDBConstruct 1–118； UniProt 2–119

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	9yya
Deposition date deposition_date	2025-10-28
Last revision last_revision	2025-11-12
Structure title title	Macrophage Migration Inhibitory Factor 1 from Necator Americanus
Keywords keywords	Cytokine, orthologue, helminth, parasite; CYTOKINE
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9yya__assembly_2__model_1

Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9yya__assembly_2__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

9yya__assembly_2__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	20.39 Å
Rg (electron density)	19.16 Å
Total Rg	20.08 Å
Atom count	5552
Residues	352
Excluded volume	48833 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`9yya__assembly_1__model_1`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`9yya__assembly_2__model_1`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	1	`9yya__assembly_3__model_1`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	1	`9yya__assembly_4__model_1`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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Unit-cell length a length_a	124.632 Å
Unit-cell length b length_b	126.213 Å
Unit-cell length c length_c	155.766 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	48

Space group space_group	P 21 21 21
Space-group number int_tables_number	19
Crystal system crystal_system	—

Resolution resolution	2.098 Å
Low-resolution limit resolution_low	98.255 Å
R factor r_factor	—
R_work r_work	0.1976
R_free r_free	0.2397

Description description	Macrophage migration inhibitory factor
Molecular weight formula_weight	12958.0 kDa
Source method src_method	man
Copy count entity_count	12

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D,E,F,G,H,I,J,K,L
Atom count atom_count	22415

Macrophage Migration Inhibitory Factor 1 from Necator Americanus

1. Protein Identity and Related Structures Protein Identity & Related Structures

Macrophage migration inhibitory factor

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

9yya__assembly_2__model_1

9yya__assembly_2__model_1 | I(q)

9yya__assembly_2__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 water

7. Citations (1)

Source organism organism	Necator americanus
Common name common_name	New World hookworm
NCBI taxonomy ID ncbi_taxonomy_id	51031
Host organism host_organism	;Escherichia coli 'BL21-Gold(DE3)pLysS AG' ;

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	230

Macrophage Migration Inhibitory Factor 1 from Necator Americanus

1. Protein Identity and Related Structures Protein Identity & Related Structures

Macrophage migration inhibitory factor

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

9yya__assembly_2__model_1

9yya__assembly_2__model_1 | I(q)

9yya__assembly_2__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 water

7. Citations (1)