Menin
Homo sapiens
State in the Current Structure
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein monomer | Monomer | Protein 1 | BETA-MERCAPTOETHANOL × 1 ;N-ethyl-5-fluoro-2-{[5-(2-{(3R)-6-[(2-methoxyethyl)(methyl)amino]-2-methylhexan-3-yl}-2,6-diazaspiro[3.4]octan-6-yl)-1,2,4-triazin-6-yl]oxy}-N-(propan-2-yl)benzamide ; × 1 SODIUM ION × 1 GLYCEROL × 1 SULFATE ION × 1 water × 1 | Consistent with protein count |
| 2 | Protein monomer | Monomer | Protein 1 | BETA-MERCAPTOETHANOL × 1 ;N-ethyl-5-fluoro-2-{[5-(2-{(3R)-6-[(2-methoxyethyl)(methyl)amino]-2-methylhexan-3-yl}-2,6-diazaspiro[3.4]octan-6-yl)-1,2,4-triazin-6-yl]oxy}-N-(propan-2-yl)benzamide ; × 1 SODIUM ION × 1 GLYCEROL × 2 water × 1 | Consistent with protein count |
| 3 | Protein monomer | Monomer | Protein 1 | ;N-ethyl-5-fluoro-2-{[5-(2-{(3R)-6-[(2-methoxyethyl)(methyl)amino]-2-methylhexan-3-yl}-2,6-diazaspiro[3.4]octan-6-yl)-1,2,4-triazin-6-yl]oxy}-N-(propan-2-yl)benzamide ; × 1 SODIUM ION × 1 water × 1 | Consistent with protein count |
| 4 | Protein monomer | Monomer | Protein 1 | ;N-ethyl-5-fluoro-2-{[5-(2-{(3R)-6-[(2-methoxyethyl)(methyl)amino]-2-methylhexan-3-yl}-2,6-diazaspiro[3.4]octan-6-yl)-1,2,4-triazin-6-yl]oxy}-N-(propan-2-yl)benzamide ; × 1 SODIUM ION × 1 water × 1 | Consistent with protein count |
Other States of the Same Protein in the Database
View Construct and Data Evidence
| UniProt name | MEN1_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 3–539； UniProt 2–610 Author chain B； PDBConstruct 3–539； UniProt 2–610 Author chain C； PDBConstruct 3–539； UniProt 2–610 Author chain D； PDBConstruct 3–539； UniProt 2–610 |