9zyt
Crystal Structure of BRD4 Bromodomain BD1 in Complex with Small Molecule PLX-3618
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 9zyt |
| deposition_date | 2026-01-06 |
| title | Crystal Structure of BRD4 Bromodomain BD1 in Complex with Small Molecule PLX-3618 |
| keywords | BRD4, Bromodomain BD1, GENE REGULATION; GENE REGULATION |
| method | X-RAY DIFFRACTION |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 22.71 Å |
| rg_electron | 22.34 Å |
| i0 | 30230900.00 |
| molecular_weight | 29161.0 kDa |
| excluded_volume | 28641 ų |
| envelope_volume | 47741 ų |
| shell_volume | 18702 ų |
| envelope_diameter | 76.1 Å |
| shell_rg | 27.81 Å |
| envelope_rg | 22.30 Å |
| shape_rg | 22.35 Å |
| total_rg | 22.87 Å |
| total_atoms | 2212 |
| n_residues | 248 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 74.3 Å |
| rg_real | 22.79 Å |
| rg_real_error | 0.47 Å |
| i0_real | 3.0230e+07 |
| i0_real_error | 4.2790e+05 |
| rg_reciprocal | 22.77 Å |
| i0_reciprocal | 30230000.0000 |
| total_estimate | 0.8878 |
| solution_quality | GOOD a GOOD solution |
| n_peaks | 2 |
| r_peak_primary | 21.4 Å |
| skewness | 0.401 |
| kurtosis | -0.477 |
| angular_range | — – 0.3500 Å−1 |
| current_alpha | 0.0001 |
| highest_alpha | 10200000.0000 |
| n_real_points | 67 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.000; Oscil: 0.881; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.908; Smooth: 0.986 |