Current Protein Identity：A0A076Q3N8
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 6BHJ Structure of HIV-1 Reverse Transcriptase Bound to a 38-mer Hairpin Template-Primer RNA-DNA Aptamer Deposited 2017-10-30 | Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: trimeric（3） Review required |
Chain A
166–722（557 aa）
Chain B
168–595（428 aa）
|
Mutation：C280S, D498N Mutation：C280S | MG MAGNESIUM ION × 1 GOL GLYCEROL × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.2；278 K；10% PEG 8000, 25 mM BisTris-Propane pH 6.8, 75 mM BisTris-Propane pH 7.4, 50 mM Ammonium Sulfate, 5% glycerol, 5% sucrose
|
Resolution 2.81 Å R-free 0.244 |
| 6BHJ Structure of HIV-1 Reverse Transcriptase Bound to a 38-mer Hairpin Template-Primer RNA-DNA Aptamer Deposited 2017-10-30 | Assembly 2 Protein–DNA Homooligomer；Protein × 2 PDB declaration: trimeric（3） Review required |
Chain C
166–722（557 aa）
Chain D
168–595（428 aa）
|
Mutation：C280S, D498N Mutation：C280S | MG MAGNESIUM ION × 1 GOL GLYCEROL × 2 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.2；278 K；10% PEG 8000, 25 mM BisTris-Propane pH 6.8, 75 mM BisTris-Propane pH 7.4, 50 mM Ammonium Sulfate, 5% glycerol, 5% sucrose
|
Resolution 2.81 Å R-free 0.244 |
| 6BSG Structure of HIV-1 RT complexed with RNA/DNA hybrid in an RNA hydrolysis-off mode Deposited 2017-12-03 | Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain B
168–607（440 aa）
|
Not recorded | EFZ (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE × 1 CA CALCIUM ION × 2 GOL GLYCEROL × 4 PEG DI(HYDROXYETHYL)ETHER × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；Sodium citrate pH 5.2, CaCl2, PEG400
|
Resolution 2.44 Å R-free 0.224 |
| 6BSH Structure of HIV-1 RT complexed with RNA/DNA hybrid in the RNA hydrolysis mode Deposited 2017-12-03 | Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain B
168–607（440 aa）
|
Not recorded | EFZ (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE × 1 CA CALCIUM ION × 2 GOL GLYCEROL × 6 TAM TRIS(HYDROXYETHYL)AMINOMETHANE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；Sodium citrate pH 5.2, CaCl2, PEG400
|
Resolution 2.65 Å R-free 0.227 |
| 6BSI Structure of HIV-1 RT complexed with an RNA/DNA hybrid containing the polypurine-tract sequence Deposited 2017-12-03 | Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain B
168–607（440 aa）
|
Not recorded | EFZ (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE × 1 CA CALCIUM ION × 2 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；Sodium citrate pH 5.2, CaCl2, PEG400
|
Resolution 3.25 Å R-free 0.241 |
| 6BSJ Structure of HIV-1 RT complexed with an RNA/DNA hybrid sequence non-preferred for RNA hydrolysis Deposited 2017-12-03 | Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain B
168–607（440 aa）
|
Not recorded | EFZ (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE × 1 CA CALCIUM ION × 1 GOL GLYCEROL × 4 TAM TRIS(HYDROXYETHYL)AMINOMETHANE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；Sodium citrate pH 5.2, CaCl2, PEG400
|
Resolution 2.89 Å R-free 0.251 |
| 6VUG Diabody bound to a Reverse Transcriptase Aptamer Complex Deposited 2020-02-15 | Assembly 1 Protein–DNA Heteromer；Protein × 4 PDB declaration: pentameric（5） Consistent with all polymers |
Chain B
168–595（428 aa）
Fragment：P51 subunit, residues 168-595
|
Not recorded | SO4 SULFATE ION × 11 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；1.4 M Ammonium Sulfate
0.1 M HEPES pH 7.8
0.1 M NaCl
|
Resolution 3.00 Å R-free 0.255 |