Current Protein Identity：A0A0U2N547
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 9Z1L Structure of KIT V654A mutant with Compound 1 Deposited 2025-11-04 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
540–930（391 aa）
|
Mutation：V654A | MRD (4R)-2-METHYLPENTANE-2,4-DIOL × 1 A1CZZ N~2~-methyl-N~4~-{(5P)-5-(1-methyl-1H-pyrazol-4-yl)-4-[(propan-2-yl)oxy]pyridin-2-yl}pyrimidine-2,4-diamine × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.4；285 K；10% 2-propanol, 100 mM Na-Citrate pH 5.0, 8% PEG 4000
|
Resolution 1.54 Å R-free 0.206 |
| 9Z2S Structure of KIT V654A mutant with Compound 11 Deposited 2025-11-05 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
540–930（391 aa）
|
Mutation：V654A | DMS DIMETHYL SULFOXIDE × 2 EDO 1,2-ETHANEDIOL × 3 A1CZ3 6-[(6-amino-2-cyclopropylpyrimidin-4-yl)amino]-N-methyl-4-[(propan-2-yl)amino]pyridine-3-carboxamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.4；293 K；8% PEG 4000
0.1 M HEPES, pH 8.2
|
Resolution 2.10 Å R-free 0.230 |