Current Protein Identity：A0A1Y1C9N2
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 6W6Q WT HTLV-1 Protease in Complex with Darunavir (DRV) Deposited 2020-03-17 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
27–142（116 aa）
Chain B
27–142（116 aa）
|
Not recorded | 017 (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.2；293 K；39-41% (v/v) PEG 300, 0.1M Phosphate/Citrate Buffer pH 4.2
|
Resolution 2.10 Å R-free 0.264 |
| 6W6R WT HTLV-1 Protease in Complex with UMass6 (UM6) Deposited 2020-03-17 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
27–142（116 aa）
Chain B
27–142（116 aa）
|
Not recorded | A60 (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-3-{[(4-aminophenyl)sulfonyl](2-ethylbutyl)amino}-1-benzyl-2-hydroxypropyl]carbamate × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.2；293 K；39-41% (v/v) PEG 300, 0.1M Phosphate/Citrate Buffer pH 4.2
|
Resolution 2.05 Å R-free 0.242 |
| 6W6S WT HTLV-1 Protease in Complex with Phosphonated UMass6 (PU6) Deposited 2020-03-17 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
27–142（116 aa）
Chain B
27–142（116 aa）
|
Not recorded | TK7 diethyl [(4-{(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-ethylbutyl)amino}-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxybutyl}phenoxy)methyl]phosphonate × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.2；293 K；39-41% (v/v) PEG 300, 0.1M Phosphate/Citrate Buffer pH 4.2
|
Resolution 2.29 Å R-free 0.306 |
| 9ZVR Crystal structure of HTLV-1 protease bound to darunavir at 2.1 angstroms with truncated flaps Deposited 2025-12-30 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
27–142（116 aa）
Chain B
27–142（116 aa）
|
Not recorded | PG4 TETRAETHYLENE GLYCOL × 1 017 (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE × 1 DMS DIMETHYL SULFOXIDE × 1 PO4 PHOSPHATE ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.2；293 K；39-41% (v/v) PEG 300, 0.1M Phosphate/Citrate Buffer pH 4.2
|
Resolution 2.10 Å R-free 0.253 |
| 9ZYE Crystal structure of HTLV-1 protease bound to UMass6 at 2.7 angstroms with truncated flaps Deposited 2026-01-05 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
27–142（116 aa）
Chain B
27–142（116 aa）
|
Not recorded | PG4 TETRAETHYLENE GLYCOL × 1 A60 (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-3-{[(4-aminophenyl)sulfonyl](2-ethylbutyl)amino}-1-benzyl-2-hydroxypropyl]carbamate × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.2；293 K；39-41% (v/v) PEG 300, 0.1M Phosphate/Citrate Buffer pH 4.2
|
Resolution 2.70 Å R-free 0.282 |