当前蛋白身份：A0MGZ7
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差异标签只比较当前检索结果；所有PDB和assembly原始记录仍分别保留。
相关结构差异明细
一行代表一个 PDB 条目中的一个 biological assembly；同一蛋白的多个单体会分别列出。
| PDB 条目 | Assembly / 聚集状态 | 构建体 | 突变与修饰 | 配体、离子与非聚合物 | 实验方法 | 实验环境 | 结构质量 |
|---|---|---|---|---|---|---|---|
| 5T03 Crystal structure of heparan sulfate 6-O-sulfotransferase with bound PAP and glucuronic acid containing hexasaccharide substrate 提交 2016-08-15 | Assembly 1 信息不足 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
75–395（321 aa）
|
突变：D82A, K83A, E172A, N173A, K239A, E359A, K362A, D363A | A3P ADENOSINE-3'-5'-DIPHOSPHATE × 1 NPO P-NITROPHENOL × 1 EDO 1,2-ETHANEDIOL × 11 CL CHLORIDE ION × 3 NA SODIUM ION × 4 TLA L(+)-TARTARIC ACID × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；100mM Tris pH 7.5, 200mM di-sodium tartrate, 18-19% PEG 3350
|
分辨率 2.10 Å R-free 0.212 |
| 5T03 Crystal structure of heparan sulfate 6-O-sulfotransferase with bound PAP and glucuronic acid containing hexasaccharide substrate 提交 2016-08-15 | Assembly 2 信息不足 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 B
75–395（321 aa）
|
突变：D82A, K83A, E172A, N173A, K239A, E359A, K362A, D363A | A3P ADENOSINE-3'-5'-DIPHOSPHATE × 1 NPO P-NITROPHENOL × 1 EDO 1,2-ETHANEDIOL × 5 CL CHLORIDE ION × 2 NA SODIUM ION × 2 TLA L(+)-TARTARIC ACID × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；100mM Tris pH 7.5, 200mM di-sodium tartrate, 18-19% PEG 3350
|
分辨率 2.10 Å R-free 0.212 |
| 5T05 Crystal structure of heparan sulfate 6-O-sulfotransferase with bound PAP and IdoA2S containing hexasaccharide substrate 提交 2016-08-15 | Assembly 1 信息不足 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
75–395（321 aa）
|
突变：D82A, K83A, E172A, N173A, K239A, E359A, K362A, D363A | A3P ADENOSINE-3'-5'-DIPHOSPHATE × 1 NPO P-NITROPHENOL × 1 EDO 1,2-ETHANEDIOL × 9 CL CHLORIDE ION × 3 NA SODIUM ION × 5 TLA L(+)-TARTARIC ACID × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；100mM Tris pH 7.5, 200mM disodium tartrate, 18-19% PEG 3350, 1mM PAP, 5mM maltose, 10mM oligosaccharide ligand
|
分辨率 1.95 Å R-free 0.212 |
| 5T05 Crystal structure of heparan sulfate 6-O-sulfotransferase with bound PAP and IdoA2S containing hexasaccharide substrate 提交 2016-08-15 | Assembly 2 信息不足 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 B
75–395（321 aa）
|
突变：D82A, K83A, E172A, N173A, K239A, E359A, K362A, D363A | A3P ADENOSINE-3'-5'-DIPHOSPHATE × 1 NPO P-NITROPHENOL × 1 EDO 1,2-ETHANEDIOL × 6 CL CHLORIDE ION × 1 NA SODIUM ION × 2 TLA L(+)-TARTARIC ACID × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；100mM Tris pH 7.5, 200mM disodium tartrate, 18-19% PEG 3350, 1mM PAP, 5mM maltose, 10mM oligosaccharide ligand
|
分辨率 1.95 Å R-free 0.212 |
| 5T0A Crystal Structure of Heparan Sulfate 6-O-Sulfotransferase with bound PAP and heptasaccharide substrate 提交 2016-08-15 | Assembly 1 信息不足 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
75–395（321 aa）
|
突变：D82A, K83A, E172A, N173A, K239A, E359A, K362A, D363A | NPO P-NITROPHENOL × 1 A3P ADENOSINE-3'-5'-DIPHOSPHATE × 1 EDO 1,2-ETHANEDIOL × 11 TLA L(+)-TARTARIC ACID × 2 NA SODIUM ION × 4 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；25mM Tris pH 7.5
200mM disodium tartrate
18-19% PEG3350
1mM PAP
10mM oligosaccharide
5mM maltose
|
分辨率 1.95 Å R-free 0.213 |
| 5T0A Crystal Structure of Heparan Sulfate 6-O-Sulfotransferase with bound PAP and heptasaccharide substrate 提交 2016-08-15 | Assembly 2 信息不足 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 B
75–395（321 aa）
|
突变：D82A, K83A, E172A, N173A, K239A, E359A, K362A, D363A | NPO P-NITROPHENOL × 1 A3P ADENOSINE-3'-5'-DIPHOSPHATE × 1 EDO 1,2-ETHANEDIOL × 4 TLA L(+)-TARTARIC ACID × 1 NA SODIUM ION × 2 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；25mM Tris pH 7.5
200mM disodium tartrate
18-19% PEG3350
1mM PAP
10mM oligosaccharide
5mM maltose
|
分辨率 1.95 Å R-free 0.213 |