Current Protein Identity:O00170 New Search
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
2LKN Solution structure of the PPIase domain of human aryl-hydrocarbon receptor-interacting protein (AIP) Deposited 2011-10-17 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 2–166(165 aa) Fragment:PPIase FKBP-type domain containing residues 1-166
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7.5;298 K;Ionic strength (raw mmCIF value) 10;Pressure ambient
NMR sample composition 2 mM AIP, 10 mM sodium phosphate, 5 mM DTT, 0.05 mM sodium azide, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition 2 mM [U-15N] AIP, 10 mM sodium phosphate, 5 mM DTT, 0.05 mM sodium azide, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition 2 mM [U-13C; U-15N] AIP, 10 mM sodium phosphate, 5 mM DTT, 0.05 mM sodium azide, 95% H2O/5% D2O | 95% H2O/5% D2O
Resolution not provided
4AIF AIP TPR domain in complex with human Hsp90 peptide Deposited 2012-02-09 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 172–315(144 aa) Fragment:TETRATRICOPEPTIDE DOMAIN, RESIDUES 172-315
Mutation:YES SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions 1 M AMMONIUM SULFATE, 0.1 M BIS-TRIS PH 5.5, 1% PEG 3350
Resolution 2.01 Å R-free 0.236
4AIF AIP TPR domain in complex with human Hsp90 peptide Deposited 2012-02-09 Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain B 172–315(144 aa) Fragment:TETRATRICOPEPTIDE DOMAIN, RESIDUES 172-315
Mutation:YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 1 M AMMONIUM SULFATE, 0.1 M BIS-TRIS PH 5.5, 1% PEG 3350
Resolution 2.01 Å R-free 0.236
4APO AIP TPR domain in complex with human Tomm20 peptide Deposited 2012-04-04 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 166–330(165 aa) Fragment:TETRATRICOPEPTIDE REPEAT DOMAIN, RESIDUES 172-313
Mutation:YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions PEG 3350, AMMONIUM SULFATE, BIS-TRIS PH 5.5
Resolution 1.90 Å R-free 0.234
4APO AIP TPR domain in complex with human Tomm20 peptide Deposited 2012-04-04 Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain B 166–330(165 aa) Fragment:TETRATRICOPEPTIDE REPEAT DOMAIN, RESIDUES 172-313
Mutation:YES 12P DODECAETHYLENE GLYCOL × 1 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions PEG 3350, AMMONIUM SULFATE, BIS-TRIS PH 5.5
Resolution 1.90 Å R-free 0.234
7ZUB Cryo-EM structure of the indirubin-bound Hsp90-XAP2-AHR complex Deposited 2022-05-12 Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count
Chain C 1–330(330 aa)
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 2 MG MAGNESIUM ION × 2 MOO MOLYBDATE ION × 2 JY6 (3~{Z})-3-(3-oxidanylidene-1~{H}-indol-2-ylidene)-1~{H}-indol-2-one × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.85 Å
8QMO Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex Deposited 2023-09-24 Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count
Chain C 1–330(330 aa)
Not recorded MOO MOLYBDATE ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 MG MAGNESIUM ION × 2 W62 benzo[a]pyrene × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.76 Å