Current Protein Identity:O00170
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2LKN Solution structure of the PPIase domain of human aryl-hydrocarbon receptor-interacting protein (AIP) Deposited 2011-10-17 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
2–166(165 aa)
Fragment:PPIase FKBP-type domain containing residues 1-166
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7.5;298 K;Ionic strength (raw mmCIF value) 10;Pressure ambient
NMR sample composition
2 mM AIP, 10 mM sodium phosphate, 5 mM DTT, 0.05 mM sodium azide, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition
2 mM [U-15N] AIP, 10 mM sodium phosphate, 5 mM DTT, 0.05 mM sodium azide, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition
2 mM [U-13C; U-15N] AIP, 10 mM sodium phosphate, 5 mM DTT, 0.05 mM sodium azide, 95% H2O/5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 4AIF AIP TPR domain in complex with human Hsp90 peptide Deposited 2012-02-09 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
172–315(144 aa)
Fragment:TETRATRICOPEPTIDE DOMAIN, RESIDUES 172-315
|
Mutation:YES | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
1 M AMMONIUM SULFATE, 0.1 M BIS-TRIS PH 5.5, 1% PEG 3350
|
Resolution 2.01 Å R-free 0.236 |
| 4AIF AIP TPR domain in complex with human Hsp90 peptide Deposited 2012-02-09 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
172–315(144 aa)
Fragment:TETRATRICOPEPTIDE DOMAIN, RESIDUES 172-315
|
Mutation:YES | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
1 M AMMONIUM SULFATE, 0.1 M BIS-TRIS PH 5.5, 1% PEG 3350
|
Resolution 2.01 Å R-free 0.236 |
| 4APO AIP TPR domain in complex with human Tomm20 peptide Deposited 2012-04-04 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
166–330(165 aa)
Fragment:TETRATRICOPEPTIDE REPEAT DOMAIN, RESIDUES 172-313
|
Mutation:YES | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
PEG 3350, AMMONIUM SULFATE, BIS-TRIS PH 5.5
|
Resolution 1.90 Å R-free 0.234 |
| 4APO AIP TPR domain in complex with human Tomm20 peptide Deposited 2012-04-04 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
166–330(165 aa)
Fragment:TETRATRICOPEPTIDE REPEAT DOMAIN, RESIDUES 172-313
|
Mutation:YES | 12P DODECAETHYLENE GLYCOL × 1 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
PEG 3350, AMMONIUM SULFATE, BIS-TRIS PH 5.5
|
Resolution 1.90 Å R-free 0.234 |
| 7ZUB Cryo-EM structure of the indirubin-bound Hsp90-XAP2-AHR complex Deposited 2022-05-12 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain C
1–330(330 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 2 MG MAGNESIUM ION × 2 MOO MOLYBDATE ION × 2 JY6 (3~{Z})-3-(3-oxidanylidene-1~{H}-indol-2-ylidene)-1~{H}-indol-2-one × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.85 Å |
| 8QMO Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex Deposited 2023-09-24 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain C
1–330(330 aa)
|
Not recorded | MOO MOLYBDATE ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 MG MAGNESIUM ION × 2 W62 benzo[a]pyrene × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.76 Å |