Current Protein Identity：O15381
New Search
Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2X8A Human Nuclear Valosin containing protein Like (NVL), C-terminal AAA- ATPase domain Deposited 2010-03-08 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
574–845（272 aa）
Fragment：C-TERMINAL AAA-ATPASE DOMAIN, 574-845
|
Not recorded | PO4 PHOSPHATE ION × 2 | X-RAY DIFFRACTION | mmCIF provides none of the parsed conditions | Resolution 2.60 Å R-free 0.250 |
| 6RO1 X-ray crystal structure of the MTR4 NVL complex Deposited 2019-05-10 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
167–216（50 aa）
|
Not recorded | SO4 SULFATE ION × 6 ADP ADENOSINE-5'-DIPHOSPHATE × 1 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；0.1M Tris/HCl pH 8.0, 1.8M Ammonium Sulphate
|
Resolution 3.07 Å R-free 0.257 |
| 9BJI Cryo-EM structure of apo NVL Deposited 2024-04-25 | Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric（7） Consistent with protein count |
Chain A
1–856（856 aa）
Chain B
1–856（856 aa）
Chain C
1–856（856 aa）
Chain D
1–856（856 aa）
Chain E
1–856（856 aa）
Chain F
1–856（856 aa）
|
Mutation：E365Q,E682Q Mutation：E365Q,E682Q Mutation：E365Q,E682Q Mutation：E365Q,E682Q Mutation：E365Q,E682Q Mutation：E365Q,E682Q | ATP ADENOSINE-5'-TRIPHOSPHATE × 9 MG MAGNESIUM ION × 8 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.83 Å |
| 9BJJ Cryo-EM structure of NVL bound the the MM017 inhibitor Deposited 2024-04-25 | Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric（7） Consistent with protein count |
Chain A
1–856（856 aa）
Chain B
1–856（856 aa）
Chain C
1–856（856 aa）
Chain D
1–856（856 aa）
Chain E
1–856（856 aa）
Chain F
1–856（856 aa）
|
Mutation：E365Q, E682Q Mutation：E365Q, E682Q Mutation：E365Q, E682Q Mutation：E365Q, E682Q Mutation：E365Q, E682Q Mutation：E365Q, E682Q | ATP ADENOSINE-5'-TRIPHOSPHATE × 9 MG MAGNESIUM ION × 8 A1AP0 N-[10-(2-methoxyethyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]furan-3-carboxamide × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.06 Å |
| 9NYP Cryo-EM structure of NVL bound the the MM927 inhibitor Deposited 2025-03-28 | Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric（7） Consistent with protein count |
Chain A
1–856（856 aa）
Chain B
1–856（856 aa）
Chain C
1–856（856 aa）
Chain D
1–856（856 aa）
Chain E
1–856（856 aa）
Chain F
1–856（856 aa）
|
Mutation：E366Q,E683Q Mutation：E366Q,E683Q Mutation：E366Q,E683Q Mutation：E366Q,E683Q Mutation：E366Q,E683Q Mutation：E366Q,E683Q | ATP ADENOSINE-5'-TRIPHOSPHATE × 9 MG MAGNESIUM ION × 8 ADP ADENOSINE-5'-DIPHOSPHATE × 1 A1B7F N-[10-(but-2-yn-1-yl)-3-fluoro-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepin-7-yl]-3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazole-5-carboxamide × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.86 Å |