Current Protein Identity：O28597
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1ICI CRYSTAL STRUCTURE OF A SIR2 HOMOLOG-NAD COMPLEX Deposited 2001-04-01 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–245（245 aa）
Chain B
1–245（245 aa）
|
Not recorded | ZN ZINC ION × 2 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6；289 K；PEG 10000, MES, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 2.10 Å R-free 0.249 |
| 1ICI CRYSTAL STRUCTURE OF A SIR2 HOMOLOG-NAD COMPLEX Deposited 2001-04-01 | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–245（245 aa）
|
Not recorded | ZN ZINC ION × 2 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6；289 K；PEG 10000, MES, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 2.10 Å R-free 0.249 |
| 1ICI CRYSTAL STRUCTURE OF A SIR2 HOMOLOG-NAD COMPLEX Deposited 2001-04-01 | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1–245（245 aa）
|
Not recorded | ZN ZINC ION × 2 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6；289 K；PEG 10000, MES, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 2.10 Å R-free 0.249 |
| 1M2G Sir2 homologue-ADP ribose complex Deposited 2002-06-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–245（245 aa）
|
Not recorded | ZN ZINC ION × 1 APR ADENOSINE-5-DIPHOSPHORIBOSE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；291 K；Sodium Citrate, PEG 4000, pH 6.0, EVAPORATION, temperature 291K
|
Resolution 1.70 Å R-free 0.220 |
| 1M2H Sir2 homologue S24A mutant-ADP ribose complex Deposited 2002-06-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–245（245 aa）
|
Mutation：S24A | ZN ZINC ION × 1 APR ADENOSINE-5-DIPHOSPHORIBOSE × 1 | X-RAY DIFFRACTION | mmCIF provides none of the parsed conditions | Resolution 1.80 Å R-free 0.215 |
| 1M2J Sir2 homologue H80N mutant-ADP ribose complex Deposited 2002-06-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–245（245 aa）
|
Mutation：H80N | ZN ZINC ION × 1 APR ADENOSINE-5-DIPHOSPHORIBOSE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；291 K；PEG 4000, Sodium Citrate, Isopropanol, pH 6.0, EVAPORATION, temperature 291K
|
Resolution 1.70 Å R-free 0.218 |
| 1M2K Sir2 homologue F159A mutant-ADP ribose complex Deposited 2002-06-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–245（245 aa）
|
Mutation：F159A | ZN ZINC ION × 1 APR ADENOSINE-5-DIPHOSPHORIBOSE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；291 K；PEG 4000, Sodium Citrate, Isopropanol, pH 6.0, EVAPORATION, temperature 291K
|
Resolution 1.47 Å R-free 0.231 |
| 1M2N Sir2 homologues (D102G/F159A/R170A) mutant-2'-O-acetyl ADP ribose complex Deposited 2002-06-24 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–245（245 aa）
Chain B
1–245（245 aa）
|
Mutation：D102G, F159A, R170A Mutation：D102G, F159A, R170A | ZN ZINC ION × 2 OAD 2'-O-ACETYL ADENOSINE-5-DIPHOSPHORIBOSE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 7；291 K；PEG 8000, HEPES, pH 7.0, EVAPORATION, temperature 291K
|
Resolution 2.60 Å R-free 0.308 |
| 4TWI The structure of Sir2Af1 bound to a succinylated histone peptide Deposited 2014-06-30 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–245（245 aa）
|
Not recorded | ZN ZINC ION × 1 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；0.1 M Tris pH 8.5, 200 mM MgCl2, and 20% (w/v) PEG 8,000
|
Resolution 1.79 Å R-free 0.221 |