Current Protein Identity：O75604
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2HD5 USP2 in complex with ubiquitin Deposited 2006-06-20 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
258–605（348 aa）
Fragment：residues 258-605
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
LIQUID DIFFUSION；pH 6.5；295 K；200 mM MgCl2, 25% PEG 3550, 100 mM Bis-Tris, Protein at 11.8 mg/ml, pH 6.5, LIQUID DIFFUSION, temperature 295K
|
Resolution 1.85 Å R-free 0.229 |
| 2IBI Covalent Ubiquitin-USP2 Complex Deposited 2006-09-11 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
250–605（356 aa）
Fragment：CATALYTIC DOMAIN, RESIDUES 251-605
|
Mutation：E472A, K473A | ZN ZINC ION × 1 NEH ETHANAMINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 9；298 K；22% PEG1500, 0.1 M Bicine, 0.2 M
NaCl, 1 mM DTT, pH 9, VAPOR DIFFUSION, SITTING DROP, temperature 298K, pH 9.00
|
Resolution 2.20 Å R-free 0.259 |
| 3NHE High Resolution Structure (1.26A) of USP2a in Complex with Ubiquitin Deposited 2010-06-14 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
258–605（348 aa）
Fragment：UNP residues 258-605
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.8；295 K；5% PEG4000, 0.1M Hepes, pH 7.8, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 1.26 Å R-free 0.189 |
| 3V6C Crystal Structure of USP2 in complex with mutated ubiquitin Deposited 2011-12-19 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
258–605（348 aa）
|
Not recorded | CL CHLORIDE ION × 2 GOL GLYCEROL × 1 ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；21% PEG 3350,0.2 M CaCl,
0.1 Bis-Tris pH 7.0,
glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.70 Å R-free 0.220 |
| 3V6E Crystal Structure of USP2 and a mutant form of Ubiquitin Deposited 2011-12-19 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
258–605（348 aa）
|
Not recorded | ZN ZINC ION × 1 CL CHLORIDE ION × 2 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；21% PEG3350, 0.2 M Calcium Chloride,0.1 Bis-Tris pH 7.0,
glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.10 Å R-free 0.234 |
| 5XU8 Crystal structure of human USP2 in complex with ubiquitin and 6-thioguanine Deposited 2017-06-22 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
258–605（348 aa）
Fragment：UNP residues 258-605
|
Not recorded | DX4 2-amino-1,9-dihydro-6H-purine-6-thione × 1 ZN ZINC ION × 1 CL CHLORIDE ION × 5 NA SODIUM ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；24.5% PEG3350, 0.2 M MgC12, 0.1 M Bis-Tris
|
Resolution 1.81 Å R-free 0.238 |
| 5XVE Crystal structure of human USP2 C276S mutant in complex with ubiquitin Deposited 2017-06-27 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
258–605（348 aa）
Fragment：UNP residues 258-605
|
Mutation：C276S | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；295 K；21% PEG3350, 8% Tacsimate (pH8.0)
|
Resolution 1.24 Å R-free 0.164 |
| 6DGF Ubiquitin Variant bound to USP2 Deposited 2018-05-17 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
250–605（356 aa）
|
Not recorded | ZN ZINC ION × 1 SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6；293 K；0.1 M MES buffer pH 6, 12% (w/v) PEG3350, 0.2M sodium sulfate
|
Resolution 2.34 Å R-free 0.224 |