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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：O88522 New Search
6PDB entries
7Biological assembly
14chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
2V4H NEMO CC2-LZ domain - 1D5 DARPin complex Deposited 2008-09-22 Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain A 251–337（87 aa） Fragment：CC2-LZ DOMAIN, RESIDUES 251-337
Chain B 251–337（87 aa） Fragment：CC2-LZ DOMAIN, RESIDUES 251-337
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；5% MPD, 5% ETHANOL, 100 MM HEPES, PH 7.5
Resolution 2.90 Å R-free 0.268
2ZVN NEMO CoZi domain incomplex with diubiquitin in P212121 space group Deposited 2008-11-12 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 253–337（85 aa） Fragment：CC2-LZ, CoZi domain
Chain D 253–337（85 aa） Fragment：CC2-LZ, CoZi domain
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；VAPOR DIFFUSION, HANGING DROP
Resolution 3.00 Å R-free 0.303
2ZVN NEMO CoZi domain incomplex with diubiquitin in P212121 space group Deposited 2008-11-12 Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain F 253–337（85 aa） Fragment：CC2-LZ, CoZi domain
Chain H 253–337（85 aa） Fragment：CC2-LZ, CoZi domain
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；VAPOR DIFFUSION, HANGING DROP
Resolution 3.00 Å R-free 0.303
2ZVO NEMO CoZi domain in complex with diubiquitin in C2 space group Deposited 2008-11-12 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 250–339（90 aa） Fragment：CC2-LZ, CoZi domain
Chain D 250–339（90 aa） Fragment：CC2-LZ, CoZi domain
Mutation：E282A, K285A Mutation：E282A, K285A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；VAPOR DIFFUSION, SITTING DROP
Resolution 2.90 Å R-free 0.277
3F89 NEMO CoZi domain Deposited 2008-11-11 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 250–339（90 aa） Fragment：CC2-LZ, CoZi domain
Chain B 250–339（90 aa） Fragment：CC2-LZ, CoZi domain
Mutation：K285N Mutation：K285N No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；VAPOR DIFFUSION, HANGING DROP
Resolution 2.80 Å R-free 0.310
3JSV Crystal structure of mouse NEMO CoZi in complex with Lys63-linked di-ubiquitin Deposited 2009-09-11 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain C 250–343（94 aa） Fragment：residues 250-343
Chain D 250–343（94 aa） Fragment：residues 250-343
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；pH 7, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 2.70 Å R-free 0.294
4OWF Crystal structure of the NEMO CoZi in complex with HOIP NZF1 domain Deposited 2014-01-31 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 250–339（90 aa）
Chain B 250–339（90 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；Co-crystals were obtained after 6 days in 20% (w/v) PEG-3350 and 0.2 M DL-malic acid
Resolution 2.00 Å R-free 0.313

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.