Current Protein Identity:P03252
New Search
Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1AVP STRUCTURE OF HUMAN ADENOVIRUS 2 PROTEINASE WITH ITS 11 AMINO ACID COFACTOR Deposited 1996-04-04 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–204(204 aa)
Fragment:MAIN
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5;pH 6.5
|
Resolution 2.60 Å R-free 0.233 |
| 1NLN CRYSTAL STRUCTURE OF HUMAN ADENOVIRUS 2 PROTEINASE WITH ITS 11 AMINO ACID COFACTOR AT 1.6 ANGSTROM RESOLUTION Deposited 2003-01-07 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–204(204 aa)
Fragment:adenovirus proteinase
|
Not recorded | ACY ACETIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;cacodylate, sodium acetate, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.60 Å R-free 0.179 |
| 4EKF Structure of the Inactive Adenovirus Proteinase at 0.98 Angstrom Resolution Deposited 2012-04-09 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–204(204 aa)
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | NA SODIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 5.6;293 K;0.3M sodium citrate, pH 5.6, 0.8 M sodium acetate, 5 mM DTT, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 0.98 Å R-free 0.168 |
| 4PID Crystal structure of human adenovirus 2 protease with a weak pyrimidine nitrile inhibitor Deposited 2014-05-08 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–204(204 aa)
|
Not recorded | ACT ACETATE ION × 1 2UQ N-benzyl-2-[(Z)-iminomethyl]pyrimidine-5-carboxamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7.5;293 K;0.8 M sodium/potassium tartrate, 0.1 M HEPES pH 7.5
|
Resolution 1.59 Å R-free 0.189 |
| 4PIE Crystal structure of human adenovirus 2 protease a substrate based nitrile inhibitor Deposited 2014-05-08 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–204(204 aa)
|
Not recorded | 3FO N-{(2S)-2-(3-chlorophenyl)-2-[(methylsulfonyl)amino]acetyl}-L-phenylalanyl-N-[(2Z)-2-iminoethyl]glycinamide × 1 SO4 SULFATE ION × 2 ZN ZINC ION × 1 ACT ACETATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4.6;293 K;1mM peptide-nitrile inhibitor was added to the protein and incubated for 30 minutes. 0.8M lithium sulphate, 0.1 M sodium acetate, pH 4.6
|
Resolution 1.94 Å R-free 0.260 |
| 5FGY Structure of human adenovirus 2 protease with cofactor pVIC Deposited 2015-12-21 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–204(204 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6.4;277.15 K;Grew over one week at 4 degrees Celsius in 0.1 M sodium citrate pH 6.4, 1.7 M sodium acetate, 1 mM DTT
|
Resolution 2.10 Å R-free 0.197 |