Current Protein Identity:P06243
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 7P5Z Structure of a DNA-loaded MCM double hexamer engaged with the Dbf4-dependent kinase Deposited 2021-07-15 | Assembly 1 Protein–DNA Heteromer;Protein × 14 PDB declaration: hexadecameric(16) Consistent with all polymers |
Chain 1
1–507(507 aa)
|
Not recorded | ATP ADENOSINE-5'-TRIPHOSPHATE × 2 MG MAGNESIUM ION × 10 ZN ZINC ION × 11 ADP ADENOSINE-5'-DIPHOSPHATE × 8 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE;blotted for 3 seconds before plunging
|
Resolution 3.30 Å |
| 7PT6 Structure of MCM2-7 DH complexed with Cdc7-Dbf4 in the presence of ATPgS, state III Deposited 2021-09-26 | Assembly 1 Protein heterocomplex Heteromer;Protein × 18 PDB declaration: octadecameric(18) Consistent with protein count |
Chain 8
1–507(507 aa)
Chain H
1–507(507 aa)
|
Not recorded | AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 12 MG MAGNESIUM ION × 14 ZN ZINC ION × 14 ADP ADENOSINE-5'-DIPHOSPHATE × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE;blot for 1.5 seconds and blot force +2
|
Resolution 3.20 Å |
| 7PT7 Structure of MCM2-7 DH complexed with Cdc7-Dbf4 in the presence of ADP:BeF3, state I Deposited 2021-09-26 | Assembly 1 Protein heterocomplex Heteromer;Protein × 15 PDB declaration: pentadecameric(15) Consistent with protein count |
Chain 8
1–507(507 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 13 MG MAGNESIUM ION × 14 ZN ZINC ION × 12 BEF BERYLLIUM TRIFLUORIDE ION × 7 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE;blot for 1.5 seconds and blot force +2
|
Resolution 3.80 Å |
| 7V3V Cryo-EM structure of MCM double hexamer bound with DDK in State I Deposited 2021-08-11 | Assembly 1 Protein heterocomplex Heteromer;Protein × 14 PDB declaration: tetradecameric(14) Consistent with protein count |
Chain H
1–507(507 aa)
|
Not recorded | AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 11 MG MAGNESIUM ION × 12 ZN ZINC ION × 11 ADP ADENOSINE-5'-DIPHOSPHATE × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.90 Å |