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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P07174 New Search
8PDB entries
8Biological assembly
13chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1NGR DEATH DOMAIN OF P75 LOW AFFINITY NEUROTROPHIN RECEPTOR, RESIDUES 334-418, NMR, 20 STRUCTURES Deposited 1997-01-28 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 334–418（85 aa） Fragment：DEATH DOMAIN, RESIDUES 281 - 425
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7；301 K
Resolution not provided
1SG1 Crystal Structure of the Receptor-Ligand Complex between Nerve Growth Factor and the Common Neurotrophin Receptor p75 Deposited 2004-02-22 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain X 30–190（161 aa）
Not recorded CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.3；295 K；PEG 1000, isoproponal, sodium chloride, citrate, pH 6.3, VAPOR DIFFUSION, SITTING DROP, temperature 295K
Resolution 2.40 Å R-free 0.269
2MIC NMR structure of p75 transmembrane domain in DPC micelles Deposited 2013-12-12 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 245–284（40 aa） Fragment：UNP residues 245-284
Chain B 245–284（40 aa） Fragment：UNP residues 245-284
Mutation：C36S (chain A), C136S (chain B) Mutation：C36S (chain A), C136S (chain B) No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.9；318 K；Pressure ambient
NMR sample composition 1.9 mM [U-100% 13C; U-100% 15N] p75-TM-wt, 95 mM [U-98% 2H] DPC, 20 mM sodium phosphate, 95% H2O/5% D2O | 95% H2O/5% D2O
Resolution not provided
2MJO NMR structure of p75 transmembrane domain C257A mutant in DPC micelles Deposited 2014-01-15 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 245–284（40 aa） Fragment：UNP residues 245-284
Chain B 245–284（40 aa） Fragment：UNP residues 245-284
Mutation：C14A, C36S chain A, C114A, C136S chain B Mutation：C14A, C36S chain A, C114A, C136S chain B No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.9；318 K；Pressure ambient
NMR sample composition 1.5 mM [U-100% 13C; U-100% 15N] p75-TM-C257A, 30 mM [U-98% 2H] DPC, 20 mM sodium phosphate, 95% H2O/5% D2O | 95% H2O/5% D2O
Resolution not provided
3BUK Crystal Structure of the Neurotrophin-3 and p75NTR Symmetrical Complex Deposited 2008-01-02 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain C 29–189（161 aa） Fragment：ectodomain
Chain D 29–189（161 aa） Fragment：ectodomain
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5；290 K；0.9M Lithium Sulfate, 0.05M Na Citrate, 0.7M Ammonium Sulfate, pH 5.0, EVAPORATION, temperature 290K
Resolution 2.60 Å R-free 0.288
3IJ2 Ligand-receptor structure Deposited 2009-08-03 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain X 33–193（161 aa） Fragment：UNP RESIDUES 30-190
Chain Y 33–193（161 aa） Fragment：UNP RESIDUES 30-190
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.75 Å R-free 0.274
4F42 Neurotrophin p75NTR intracellular domain Deposited 2012-05-09 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 334–418（85 aa） Fragment：death domain, UNP RESIDUES 334-418
Not recorded MNB 5-MERCAPTO-2-NITRO-BENZOIC ACID × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；277 K；0.1M Bis-Tris propane pH 7.0, 1.2M sodium citrate tribasic dehydrate, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.38 Å R-free 0.260
4F44 Neurotrophin p75NTR intracellular domain Deposited 2012-05-10 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 334–418（85 aa） Fragment：death domain
Chain B 334–418（85 aa） Fragment：death domain
Not recorded MNB 5-MERCAPTO-2-NITRO-BENZOIC ACID × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；277 K；0.1M Bis-Tris propane, 1.4M sodium malonate, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.40 Å R-free 0.280

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.