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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P07998 New Search
12PDB entries
22Biological assembly
32chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1DZA 3-D structure of a HP-RNase Deposited 2000-02-21 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 28–156（129 aa）
Mutation：YES Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5；pH 8.50
Resolution 1.65 Å R-free 0.236
1DZA 3-D structure of a HP-RNase Deposited 2000-02-21 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 28–156（129 aa）
Mutation：YES Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5；pH 8.50
Resolution 1.65 Å R-free 0.236
1E21 Ribonuclease 1 des1-7 Crystal Structure at 1.9A Deposited 2000-05-15 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 29–156（128 aa）
Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5；7% PEG 8K, 0.1M TRIS-HCL PH 8.5
Resolution 1.90 Å R-free 0.251
1H8X Domain-swapped Dimer of a Human Pancreatic Ribonuclease Variant Deposited 2001-02-16 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 29–156（128 aa） Fragment：RNASE 1, HP-RNASE
Chain B 29–156（128 aa） Fragment：RNASE 1, HP-RNASE
Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 9；pH 9.00
Resolution 2.00 Å R-free 0.243
1Z7X X-ray structure of human ribonuclease inhibitor complexed with ribonuclease I Deposited 2005-03-28 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain X 29–156（128 aa）
Chain Z 29–156（128 aa）
Not recorded CIT CITRIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.2；293 K；10% MEPEG 2000, 0.020 M SODIUM CITRATE, 0.025 M DTT, 0.001 M AMMONIUM SULFATE, vapor diffusion, HANGING DROP, temperature 293K, pH 4.2
Resolution 1.95 Å R-free 0.236
2E0J Mutant Human Ribonuclease 1 (R31L, R32L) Deposited 2006-10-10 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 29–156（128 aa）
Mutation：R31L, R32L No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.6；293 K；26% PEG 4000, 0.2M ammpnium sulfate, 0.1M sodium acetate , pH 4.6, VAPOR DIFFUSION, temperature 293K
Resolution 1.60 Å R-free 0.217
2E0J Mutant Human Ribonuclease 1 (R31L, R32L) Deposited 2006-10-10 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 29–156（128 aa）
Mutation：R31L, R32L No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.6；293 K；26% PEG 4000, 0.2M ammpnium sulfate, 0.1M sodium acetate , pH 4.6, VAPOR DIFFUSION, temperature 293K
Resolution 1.60 Å R-free 0.217
2E0L Mutant Human Ribonuclease 1 (Q28L, R31L, R32L) Deposited 2006-10-10 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 29–156（128 aa）
Mutation：Q28L, R31L, R32L CD CADMIUM ION × 5 CL CHLORIDE ION × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.6；293 K；30% PEG 400, 0.1M cadmium chloride, 0.1M sodium acetate , pH 4.6, VAPOR DIFFUSION, temperature 293K
Resolution 1.60 Å R-free 0.215
2E0L Mutant Human Ribonuclease 1 (Q28L, R31L, R32L) Deposited 2006-10-10 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 29–156（128 aa）
Mutation：Q28L, R31L, R32L CD CADMIUM ION × 3 CL CHLORIDE ION × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.6；293 K；30% PEG 400, 0.1M cadmium chloride, 0.1M sodium acetate , pH 4.6, VAPOR DIFFUSION, temperature 293K
Resolution 1.60 Å R-free 0.215
2E0L Mutant Human Ribonuclease 1 (Q28L, R31L, R32L) Deposited 2006-10-10 Assembly 3 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 29–156（128 aa）
Chain B 29–156（128 aa）
Mutation：Q28L, R31L, R32L Mutation：Q28L, R31L, R32L CD CADMIUM ION × 16 CL CHLORIDE ION × 22 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.6；293 K；30% PEG 400, 0.1M cadmium chloride, 0.1M sodium acetate , pH 4.6, VAPOR DIFFUSION, temperature 293K
Resolution 1.60 Å R-free 0.215
2E0M Mutant Human Ribonuclease 1 (T24L, Q28L, R31L, R32L) Deposited 2006-10-10 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 29–156（128 aa）
Mutation：T24L, Q28L, R31L, R32L CD CADMIUM ION × 5 CL CHLORIDE ION × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.6；293 K；30% PEG 400, 0.1M cadmium chloride, 0.1M sodium acetate, pH 4.6, VAPOR DIFFUSION, temperature 293K
Resolution 1.70 Å R-free 0.214
2E0M Mutant Human Ribonuclease 1 (T24L, Q28L, R31L, R32L) Deposited 2006-10-10 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 29–156（128 aa）
Mutation：T24L, Q28L, R31L, R32L CD CADMIUM ION × 3 CL CHLORIDE ION × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.6；293 K；30% PEG 400, 0.1M cadmium chloride, 0.1M sodium acetate, pH 4.6, VAPOR DIFFUSION, temperature 293K
Resolution 1.70 Å R-free 0.214
2E0M Mutant Human Ribonuclease 1 (T24L, Q28L, R31L, R32L) Deposited 2006-10-10 Assembly 3 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 29–156（128 aa）
Chain B 29–156（128 aa）
Mutation：T24L, Q28L, R31L, R32L Mutation：T24L, Q28L, R31L, R32L CD CADMIUM ION × 16 CL CHLORIDE ION × 22 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.6；293 K；30% PEG 400, 0.1M cadmium chloride, 0.1M sodium acetate, pH 4.6, VAPOR DIFFUSION, temperature 293K
Resolution 1.70 Å R-free 0.214
2E0O Mutant Human Ribonuclease 1 (V52L, D53L, N56L, F59L) Deposited 2006-10-10 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 29–156（128 aa）
Mutation：V52L, D53L, N56L, F59L SO4 SULFATE ION × 5 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 6.5；293 K；1.0M ammonium sulfate, 0.1M MES, pH 6.5, VAPOR DIFFUSION, temperature 293K
Resolution 2.00 Å R-free 0.255
2E0O Mutant Human Ribonuclease 1 (V52L, D53L, N56L, F59L) Deposited 2006-10-10 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 29–156（128 aa）
Mutation：V52L, D53L, N56L, F59L SO4 SULFATE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 6.5；293 K；1.0M ammonium sulfate, 0.1M MES, pH 6.5, VAPOR DIFFUSION, temperature 293K
Resolution 2.00 Å R-free 0.255
2E0O Mutant Human Ribonuclease 1 (V52L, D53L, N56L, F59L) Deposited 2006-10-10 Assembly 3 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 29–156（128 aa）
Chain B 29–156（128 aa）
Mutation：V52L, D53L, N56L, F59L Mutation：V52L, D53L, N56L, F59L SO4 SULFATE ION × 18 GOL GLYCEROL × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 6.5；293 K；1.0M ammonium sulfate, 0.1M MES, pH 6.5, VAPOR DIFFUSION, temperature 293K
Resolution 2.00 Å R-free 0.255
2E0O Mutant Human Ribonuclease 1 (V52L, D53L, N56L, F59L) Deposited 2006-10-10 Assembly 4 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 29–156（128 aa）
Chain B 29–156（128 aa）
Mutation：V52L, D53L, N56L, F59L Mutation：V52L, D53L, N56L, F59L SO4 SULFATE ION × 18 GOL GLYCEROL × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 6.5；293 K；1.0M ammonium sulfate, 0.1M MES, pH 6.5, VAPOR DIFFUSION, temperature 293K
Resolution 2.00 Å R-free 0.255
2K11 Solution structure of human pancreatic ribonuclease Deposited 2008-02-20 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 29–155（127 aa）
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 4.7；298 K；Pressure ambient
NMR sample composition 1.2 mM Human pancreatic ribonuclease, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition 1.2 mM Human pancreatic ribonuclease, 100% D2O | 100% D2O
NMR sample composition 1.2 mM [U-15N] Human pancreatic ribonuclease, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2Q4G Ensemble refinement of the protein crystal structure of human ribonuclease inhibitor complexed with ribonuclease I Deposited 2007-05-31 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain X 29–156（128 aa）
Chain Z 29–156（128 aa）
Not recorded CIT CITRIC ACID × 1 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 1.95 Å R-free 0.224
3F8G The X-ray structure of a dimeric variant of human pancreatic ribonuclease with high cytotoxic and antitumor activities Deposited 2008-11-12 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 29–153（125 aa）
Chain B 29–153（125 aa）
Mutation：Q28L, R31C, R32C, N34K, E111G Mutation：Q28L, R31C, R32C, N34K, E111G SO4 SULFATE ION × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；277 K；A protein solution of 10mg/ml in 10mM Tris acteate ph 7.0, 300mM NaCl was equilibrated against a solution containing 27% w/v PEG, 0.2 M AS, and 100mM cacodylate buffer ph 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.60 Å R-free 0.306
4KXH The X-ray crystal structure of a dimeric variant of human pancreatic ribonuclease Deposited 2013-05-26 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 29–151（123 aa） Fragment：unp residues 29-151
Chain B 29–151（123 aa） Fragment：unp residues 29-151
Not recorded SO4 SULFATE ION × 6 NA SODIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；20% PEG 8000, 0.1M ammonium sulphate, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.70 Å R-free 0.246
4KXH The X-ray crystal structure of a dimeric variant of human pancreatic ribonuclease Deposited 2013-05-26 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 29–151（123 aa） Fragment：unp residues 29-151
Chain D 29–151（123 aa） Fragment：unp residues 29-151
Not recorded SO4 SULFATE ION × 7 NA SODIUM ION × 2 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；20% PEG 8000, 0.1M ammonium sulphate, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.70 Å R-free 0.246

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.