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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P08253 New Search
11PDB entries
13Biological assembly
17chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1CK7 GELATINASE A (FULL-LENGTH) Deposited 1999-04-28 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 30–660（631 aa） Fragment：FULL-LENGTH
Mutation：E404A ZN ZINC ION × 2 CA CALCIUM ION × 3 CL CHLORIDE ION × 1 NA SODIUM ION × 1 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.8；pH 7.8
Resolution 2.80 Å R-free 0.327
1CXW THE SECOND TYPE II MODULE FROM HUMAN MATRIX METALLOPROTEINASE 2 Deposited 1999-08-31 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 278–336（59 aa） Fragment：THE SECOND TYPE II MODULE
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.2；298 K；Ionic strength (raw mmCIF value) 0；Pressure 1
NMR measurement conditions pH 5.1；298 K；Ionic strength (raw mmCIF value) 0；Pressure 1
NMR sample composition 1.3MM COL-2 NA; 90% H2O, 10% D2O
NMR sample composition 1.3MM COL-2 NA; D2O
NMR sample composition 1MM COL-2 U-15N; 90% H2O, 10% D2O
NMR sample composition 4MM COL-2 U-15N; 90% H2O, 10% D2O
Resolution not provided
1EAK Catalytic domain of proMMP-2 E404Q mutant Deposited 2001-07-12 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 32–452（421 aa） Fragment：CATALYTIC DOMAIN RESIDUES 32-452
Chain C 32–452（421 aa） Fragment：CATALYTIC DOMAIN RESIDUES 32-452
Mutation：YES Mutation：YES SO4 SULFATE ION × 3 ZN ZINC ION × 4 CA CALCIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5；PH 8.50
Resolution 2.66 Å R-free 0.303
1EAK Catalytic domain of proMMP-2 E404Q mutant Deposited 2001-07-12 Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain B 32–452（421 aa） Fragment：CATALYTIC DOMAIN RESIDUES 32-452
Chain D 32–452（421 aa） Fragment：CATALYTIC DOMAIN RESIDUES 32-452
Mutation：YES Mutation：YES SO4 SULFATE ION × 3 ZN ZINC ION × 4 CA CALCIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5；PH 8.50
Resolution 2.66 Å R-free 0.303
1GEN C-TERMINAL DOMAIN OF GELATINASE A Deposited 1995-07-19 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 443–660（218 aa） Fragment：C-TERMINAL DOMAIN
Not recorded ZN ZINC ION × 1 CA CALCIUM ION × 1 CL CHLORIDE ION × 1 NA SODIUM ION × 1 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.15 Å R-free 0.260
1GXD proMMP-2/TIMP-2 complex Deposited 2002-04-02 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 30–660（631 aa）
Mutation：YES SO4 SULFATE ION × 1 ZN ZINC ION × 2 CA CALCIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5；pH 8.50
Resolution 3.10 Å R-free 0.333
1GXD proMMP-2/TIMP-2 complex Deposited 2002-04-02 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 30–660（631 aa）
Mutation：YES SO4 SULFATE ION × 1 ZN ZINC ION × 2 CA CALCIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5；pH 8.50
Resolution 3.10 Å R-free 0.333
1HOV SOLUTION STRUCTURE OF A CATALYTIC DOMAIN OF MMP-2 COMPLEXED WITH SC-74020 Deposited 2000-12-11 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 110–256（147 aa） Fragment：CATALYTIC DOMAIN
Not recorded ZN ZINC ION × 2 CA CALCIUM ION × 2 I52 N-{4-[(1-HYDROXYCARBAMOYL-2-METHYL-PROPYL)-(2-MORPHOLIN-4-YL-ETHYL)-SULFAMOYL]-4-PENTYL-BENZAMIDE × 1 SOLUTION NMR
NMR measurement conditions pH 7.4；303 K；Ionic strength (raw mmCIF value) 50；Pressure 1
NMR sample composition 0.3-0.4mM U-15N, 13C MMP-2C: unlabeled SC-74020 in 20mM TRIS-d11-HCl, 5mM CaCl2, 10uM ZnCl2, 20uM unlabeled SC-74020 | 90% H2O/10% D2O
Resolution not provided
1J7M The Third Fibronectin Type II Module from Human Matrix Metalloproteinase 2 Deposited 2001-05-17 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 337–394（58 aa） Fragment：third fibronectin type II module
Mutation：E11G No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.4；298 K；Ionic strength (raw mmCIF value) 0；Pressure ambient
NMR sample composition 0.5mM col-3 NA; 90% H2O, 10% D2O | 90% H2O/10% D2O
NMR sample composition 0.5mM col-3 NA; D2O | D2O
NMR sample composition 1mM col-3 U-15n; 90% H2O, 10% D2O | 90% H2O/10% D2O
Resolution not provided
1KS0 The First Fibronectin Type II Module from Human Matrix Metalloproteinase 2 Deposited 2002-01-10 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 223–282（60 aa） Fragment：First Fibronectin Type II Module
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7.3；298 K；Ionic strength (raw mmCIF value) 0；Pressure ambient
NMR measurement conditions pH 6；298 K；Ionic strength (raw mmCIF value) 0；Pressure ambient
NMR sample composition 0.5mM col-1; 90% H2O, 10% d6-acetone | 90% H2O, 10% d6-acetone
NMR sample composition 0.5mM col-1; 90% D2O, 10% d6-acetone | 90% D2O, 10% d6-acetone
NMR sample composition 0.7mM col-1 15N; 90% H2O, 10% d6-acetone | 90% H2O, 10% d6-acetone
Resolution not provided
1QIB CRYSTAL STRUCTURE OF GELATINASE A CATALYTIC DOMAIN Deposited 1999-06-11 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 115–213（99 aa） Fragment：CATALYTIC DOMAIN RESIDUES 88-250 WITH THE FIBRONECTIN DOMAIN DELETED
Chain A 394–449（56 aa） Fragment：CATALYTIC DOMAIN RESIDUES 88-250 WITH THE FIBRONECTIN DOMAIN DELETED
Not recorded ZN ZINC ION × 2 CA CALCIUM ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6；pH 6.0
Resolution 2.80 Å R-free 0.244
1RTG C-TERMINAL DOMAIN (HAEMOPEXIN-LIKE DOMAIN) OF HUMAN MATRIX METALLOPROTEINASE-2 Deposited 1995-12-21 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 451–660（210 aa） Fragment：C-TERMINAL RESIDUES 451 - 660, HAEMOPEXIN-LIKE DOMAIN
Not recorded CL CHLORIDE ION × 1 CA CALCIUM ION × 2 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.60 Å
3AYU Crystal structure of MMP-2 active site mutant in complex with APP-drived decapeptide inhibitor Deposited 2011-05-17 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 110–219（110 aa） Fragment：UNP residues 110-219 and 394-450
Chain A 394–450（57 aa） Fragment：UNP residues 110-219 and 394-450
Mutation：E108K, Q110V, E121A Mutation：E108K, Q110V, E121A ZN ZINC ION × 2 CA CALCIUM ION × 3 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.00 Å R-free 0.205

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.