Current Protein Identity:P08700
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1JLI HUMAN INTERLEUKIN 3 (IL-3) MUTANT WITH TRUNCATION AT BOTH N-AND C-TERMINI AND 14 RESIDUE CHANGES, NMR, MINIMIZED AVERAGE STRUCTURE Deposited 1995-12-14 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
34–144(111 aa)
|
Mutation:DEL(1-13), V14A, N18I, T25H, Q29R, L32N, F37P, G42S, Q45M, N51R, R55T, E59L, N62V, S67H, Q69E, DEL(126-133) | No recorded non-water small molecule | SOLUTION NMR | mmCIF provides none of the parsed conditions | Resolution not provided |
| 5UV8 Interleukin-3 Receptor Complex Deposited 2017-02-19 | Assembly 1 Other combination Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
31–152(122 aa)
Fragment:UNP residues 31-152
|
Mutation:W32Y | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;298 K;20% PEG 8000, 200 mM NaCI, 100 mM
citrate-phosphate buffer pH 5
|
Resolution 2.70 Å R-free 0.286 |
| 5UV8 Interleukin-3 Receptor Complex Deposited 2017-02-19 | Assembly 2 Other combination Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain I
31–152(122 aa)
Fragment:UNP residues 31-152
|
Mutation:W32Y | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 GOL GLYCEROL × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;298 K;20% PEG 8000, 200 mM NaCI, 100 mM
citrate-phosphate buffer pH 5
|
Resolution 2.70 Å R-free 0.286 |
| 5UWC Cytokine-receptor complex Deposited 2017-02-21 | Assembly 1 Other combination Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain I
31–152(122 aa)
Fragment:UNP residues 31-152
|
Mutation:W32Y, K116W | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 CIT CITRIC ACID × 2 IMD IMIDAZOLE × 1 EDT {[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 4.8;293 K;20% PEG 8000, 200 mM NaCl and 100 mM citrate-phosphate buffer pH 4.8
|
Resolution 2.40 Å R-free 0.242 |
| 6NMY A Cytokine-receptor complex Deposited 2019-01-13 | Assembly 1 Other combination Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain J
31–144(114 aa)
|
Mutation:W13Y | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.8;277.15 K;Crystals were grown in 10 mM Tris pH6.8, 8% PEG 8000, 0.15 M magnesium chloride
|
Resolution 3.30 Å R-free 0.278 |
| 6NMY A Cytokine-receptor complex Deposited 2019-01-13 | Assembly 2 Other combination Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain I
31–144(114 aa)
|
Mutation:W13Y | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.8;277.15 K;Crystals were grown in 10 mM Tris pH6.8, 8% PEG 8000, 0.15 M magnesium chloride
|
Resolution 3.30 Å R-free 0.278 |