Current Protein Identity:P0ACB2
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1B4E X-ray structure of 5-aminolevulinic acid dehydratase complexed with the inhibitor levulinic acid Deposited 1998-12-19 | Assembly 1 Protein homooligomer Homooligomer;Protein × 8 PDB declaration: octameric(8) Consistent with protein count |
Chain A
1–323(323 aa)
|
Not recorded | SO4 SULFATE ION × 24 ZN ZINC ION × 24 SHF LAEVULINIC ACID × 8 GOL GLYCEROL × 24 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8.2;7MG/ML ENZYME AND 2 - 5 % SATURATED AMMONIUM SULPHATE AS PRECIPITANT. 0.2 M
TRIS-HCL USED TO BUFFER THE PH BETWEEN 8.1 AND 8.4. 15MM LEVULINIC ACID, 40UM
ZINC SULPHATE AND 4MM BETA- MERCAPTOETHANOL WERE PRESENT., pH 8.2, VAPOR DIFFUSION, HANGING DROP
|
Resolution 2.00 Å R-free 0.255 |
| 1I8J CRYSTAL STRUCTURE OF PORPHOBILINOGEN SYNTHASE COMPLEXED WITH THE INHIBITOR 4,7-DIOXOSEBACIC ACID Deposited 2001-03-14 | Assembly 1 Protein homooligomer Homooligomer;Protein × 8 PDB declaration: octameric(8) Consistent with protein count |
Chain A
1–323(323 aa)
Chain B
1–323(323 aa)
|
Not recorded | ZN ZINC ION × 8 MG MAGNESIUM ION × 8 DSB 4,7-DIOXOSEBACIC ACID × 8 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8.5;294 K;PEG 3350, GLYCEROL, TRIS-HCL, pH 8.5, VAPOR DIFFUSION, SITTING DROP, temperature 294K
|
Resolution 1.90 Å R-free 0.247 |
| 1L6S Crystal Structure of Porphobilinogen Synthase Complexed with the Inhibitor 4,7-Dioxosebacic Acid Deposited 2002-03-13 | Assembly 1 Protein homooligomer Homooligomer;Protein × 8 PDB declaration: octameric(8) Consistent with protein count |
Chain A
1–323(323 aa)
Chain B
1–323(323 aa)
|
Non-standard monomer:Yes (specific site not provided by mmCIF) Non-standard monomer:Yes (specific site not provided by mmCIF) | ZN ZINC ION × 8 MG MAGNESIUM ION × 8 DSB 4,7-DIOXOSEBACIC ACID × 8 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;296 K;PEG 3350, 10% GLYCEROL, 0.1M TRIS-HCL, PH 8.5, 0.02% SODIUM AZIDE, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 296K
|
Resolution 1.70 Å R-free 0.243 |
| 1L6Y Crystal Structure of Porphobilinogen Synthase Complexed with the Inhibitor 4-Oxosebacic Acid Deposited 2002-03-14 | Assembly 1 Protein homooligomer Homooligomer;Protein × 8 PDB declaration: octameric(8) Consistent with protein count |
Chain A
1–323(323 aa)
Chain B
1–323(323 aa)
|
Non-standard monomer:Yes (specific site not provided by mmCIF) Non-standard monomer:Yes (specific site not provided by mmCIF) | ZN ZINC ION × 8 MG MAGNESIUM ION × 8 4OX 4-OXODECANEDIOIC ACID × 8 GOL GLYCEROL × 20 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;296 K;PEG 3350, 10% GLYCEROL, 0.1M TRIS-HCL, PH 8.5, 0.02% SODIUM
AZIDE, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 296K
|
Resolution 1.90 Å R-free 0.263 |
| 5MHB Product-Complex of E.coli 5-Amino Laevulinic Acid Dehydratase Deposited 2016-11-23 | Assembly 1 Protein homooligomer Homooligomer;Protein × 8 PDB declaration: octameric(8) Consistent with protein count |
Chain A
1–324(324 aa)
|
Not recorded | PBG 3-[5-(AMINOMETHYL)-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC ACID × 8 ZN ZINC ION × 24 GOL GLYCEROL × 24 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8.2;293 K;ALAD at 7 mg per ml mixed with equal volume of well solution: 200 mM Tris pH 8.0 - 8.4, 2 % saturated Ammonium sulphate, 200 microM zinc sulphate, 6 mM beta-mercaptoethanol and 3 mM porphobilinogen. Crystals were grown in the dark.
|
Resolution 2.10 Å R-free 0.213 |