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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P0C7B7 New Search
18PDB entries
31Biological assembly
155chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
2VL0 X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) Deposited 2008-01-07 Assembly 1 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 1–321（321 aa）
Chain B 1–321（321 aa）
Chain C 1–321（321 aa）
Chain D 1–321（321 aa）
Chain E 1–321（321 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.5；15 % PEG 4000, 200MM AMMONIUM SULFATE, 50 MM ADA PH 6.5
Resolution 3.30 Å R-free 0.274
2VL0 X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) Deposited 2008-01-07 Assembly 2 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain F 1–321（321 aa）
Chain G 1–321（321 aa）
Chain H 1–321（321 aa）
Chain I 1–321（321 aa）
Chain J 1–321（321 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.5；15 % PEG 4000, 200MM AMMONIUM SULFATE, 50 MM ADA PH 6.5
Resolution 3.30 Å R-free 0.274
2YKS PENTAMERIC LIGAND GATED ION CHANNEL ELIC MUTANT F246A Deposited 2011-05-30 Assembly 1 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 1–321（321 aa）
Chain B 1–321（321 aa）
Chain C 1–321（321 aa）
Chain D 1–321（321 aa）
Chain E 1–321（321 aa）
Mutation：YES Mutation：YES Mutation：YES Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.5；50MM ADA PH6.5, 200MM NALISO4, 10% (W/V) PEG4000
Resolution 3.30 Å R-free 0.265
2YKS PENTAMERIC LIGAND GATED ION CHANNEL ELIC MUTANT F246A Deposited 2011-05-30 Assembly 2 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain F 1–321（321 aa）
Chain G 1–321（321 aa）
Chain H 1–321（321 aa）
Chain I 1–321（321 aa）
Chain J 1–321（321 aa）
Mutation：YES Mutation：YES Mutation：YES Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.5；50MM ADA PH6.5, 200MM NALISO4, 10% (W/V) PEG4000
Resolution 3.30 Å R-free 0.265
2YOE X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with GABA and flurazepam Deposited 2012-10-23 Assembly 1 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain F 11–316（306 aa）
Chain G 11–316（306 aa）
Chain H 11–316（306 aa）
Chain I 11–316（306 aa）
Chain J 11–316（306 aa）
Not recorded ABU GAMMA-AMINO-BUTANOIC ACID × 1 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.90 Å R-free 0.230
2YOE X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with GABA and flurazepam Deposited 2012-10-23 Assembly 2 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 11–316（306 aa）
Chain B 11–316（306 aa）
Chain C 11–316（306 aa）
Chain D 11–316（306 aa）
Chain E 11–316（306 aa）
Not recorded ABU GAMMA-AMINO-BUTANOIC ACID × 1 FL7 Flurazepam × 1 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.90 Å R-free 0.230
3ZKR X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromoform Deposited 2013-01-24 Assembly 1 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain F 11–316（306 aa）
Chain G 11–316（306 aa）
Chain H 11–316（306 aa）
Chain I 11–316（306 aa）
Chain J 11–316（306 aa）
Not recorded MBR TRIBROMOMETHANE × 11 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.65 Å R-free 0.264
3ZKR X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromoform Deposited 2013-01-24 Assembly 2 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 11–316（306 aa）
Chain B 11–316（306 aa）
Chain C 11–316（306 aa）
Chain D 11–316（306 aa）
Chain E 11–316（306 aa）
Not recorded MBR TRIBROMOMETHANE × 11 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.65 Å R-free 0.264
4A97 X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with zopiclone Deposited 2011-11-24 Assembly 1 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 11–316（306 aa） Fragment：RESIDUES 11-316
Chain B 11–316（306 aa） Fragment：RESIDUES 11-316
Chain C 11–316（306 aa） Fragment：RESIDUES 11-316
Chain D 11–316（306 aa） Fragment：RESIDUES 11-316
Chain E 11–316（306 aa） Fragment：RESIDUES 11-316
Not recorded ZPC (5R)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate × 5 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.34 Å R-free 0.259
4A97 X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with zopiclone Deposited 2011-11-24 Assembly 2 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain F 11–316（306 aa） Fragment：RESIDUES 11-316
Chain G 11–316（306 aa） Fragment：RESIDUES 11-316
Chain H 11–316（306 aa） Fragment：RESIDUES 11-316
Chain I 11–316（306 aa） Fragment：RESIDUES 11-316
Chain J 11–316（306 aa） Fragment：RESIDUES 11-316
Not recorded ZPC (5R)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate × 5 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.34 Å R-free 0.259
4A98 X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromoflurazepam Deposited 2011-11-24 Assembly 1 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 11–316（306 aa） Fragment：RESIDUES 11-316
Chain B 11–316（306 aa） Fragment：RESIDUES 11-316
Chain C 11–316（306 aa） Fragment：RESIDUES 11-316
Chain D 11–316（306 aa） Fragment：RESIDUES 11-316
Chain E 11–316（306 aa） Fragment：RESIDUES 11-316
Not recorded BFZ 7-BROMO-1-[2-(DIETHYLAMINO)ETHYL]-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE × 5 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.61 Å R-free 0.245
4A98 X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromoflurazepam Deposited 2011-11-24 Assembly 2 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain F 11–316（306 aa） Fragment：RESIDUES 11-316
Chain G 11–316（306 aa） Fragment：RESIDUES 11-316
Chain H 11–316（306 aa） Fragment：RESIDUES 11-316
Chain I 11–316（306 aa） Fragment：RESIDUES 11-316
Chain J 11–316（306 aa） Fragment：RESIDUES 11-316
Not recorded BFZ 7-BROMO-1-[2-(DIETHYLAMINO)ETHYL]-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE × 5 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.61 Å R-free 0.245
4TWD X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with memantine Deposited 2014-06-30 Assembly 1 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: Pentameric（5） Consistent with protein count
Chain A 11–316（306 aa）
Chain B 11–316（306 aa）
Chain C 11–316（306 aa）
Chain D 11–316（306 aa）
Chain E 11–316（306 aa）
Mutation：F16S Mutation：F16S Mutation：F16S Mutation：F16S Mutation：F16S 377 Memantine × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；294 K；200 mM ammonium sulphate, 50 mM ADA, pH 5.5, 20 % PEG 4000
Resolution 3.20 Å R-free 0.252
4TWD X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with memantine Deposited 2014-06-30 Assembly 2 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: Pentameric（5） Consistent with protein count
Chain F 11–316（306 aa）
Chain G 11–316（306 aa）
Chain H 11–316（306 aa）
Chain I 11–316（306 aa）
Chain J 11–316（306 aa）
Mutation：F16S Mutation：F16S Mutation：F16S Mutation：F16S Mutation：F16S 377 Memantine × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；294 K；200 mM ammonium sulphate, 50 mM ADA, pH 5.5, 20 % PEG 4000
Resolution 3.20 Å R-free 0.252
4TWF X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromomemantine Deposited 2014-06-30 Assembly 1 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: Pentameric（5） Consistent with protein count
Chain A 11–316（306 aa） Fragment：UNP residues 11-316
Chain B 11–316（306 aa） Fragment：UNP residues 11-316
Chain C 11–316（306 aa） Fragment：UNP residues 11-316
Chain D 11–316（306 aa） Fragment：UNP residues 11-316
Chain E 11–316（306 aa） Fragment：UNP residues 11-316
Mutation：F246S Mutation：F246S Mutation：F246S Mutation：F246S Mutation：F246S BR7 Bromomemantine × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；294 K；200 mM ammonium sulphate, 50 mM ADA pH 5.5, 20 % PEG 4000
Resolution 3.90 Å R-free 0.250
4TWF X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromomemantine Deposited 2014-06-30 Assembly 2 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: Pentameric（5） Consistent with protein count
Chain F 11–316（306 aa） Fragment：UNP residues 11-316
Chain G 11–316（306 aa） Fragment：UNP residues 11-316
Chain H 11–316（306 aa） Fragment：UNP residues 11-316
Chain I 11–316（306 aa） Fragment：UNP residues 11-316
Chain J 11–316（306 aa） Fragment：UNP residues 11-316
Mutation：F246S Mutation：F246S Mutation：F246S Mutation：F246S Mutation：F246S BR7 Bromomemantine × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；294 K；200 mM ammonium sulphate, 50 mM ADA pH 5.5, 20 % PEG 4000
Resolution 3.90 Å R-free 0.250
4TWH X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) mutant F16'S Deposited 2014-06-30 Assembly 1 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: Pentameric（5） Consistent with protein count
Chain A 11–316（306 aa） Fragment：UNP residues 11-316
Chain B 11–316（306 aa） Fragment：UNP residues 11-316
Chain C 11–316（306 aa） Fragment：UNP residues 11-316
Chain D 11–316（306 aa） Fragment：UNP residues 11-316
Chain E 11–316（306 aa） Fragment：UNP residues 11-316
Mutation：F246S Mutation：F246S Mutation：F246S Mutation：F246S Mutation：F246S No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；294 K；200 mM ammonium sulphate 50 mM ADA, pH 5.5 20 % PEG 4000
Resolution 3.60 Å R-free 0.263
4TWH X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) mutant F16'S Deposited 2014-06-30 Assembly 2 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: Pentameric（5） Consistent with protein count
Chain F 11–316（306 aa） Fragment：UNP residues 11-316
Chain G 11–316（306 aa） Fragment：UNP residues 11-316
Chain H 11–316（306 aa） Fragment：UNP residues 11-316
Chain I 11–316（306 aa） Fragment：UNP residues 11-316
Chain J 11–316（306 aa） Fragment：UNP residues 11-316
Mutation：F246S Mutation：F246S Mutation：F246S Mutation：F246S Mutation：F246S No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；294 K；200 mM ammonium sulphate 50 mM ADA, pH 5.5 20 % PEG 4000
Resolution 3.60 Å R-free 0.263
4YEU ELIC-GLIC chimera in the resting conformation Deposited 2015-02-24 Assembly 1 Insufficient information Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 11–199（189 aa）
Chain B 11–199（189 aa）
Chain C 11–199（189 aa）
Chain D 11–199（189 aa）
Chain E 11–199（189 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；277 K；PEG 4000, Ammonium Sulfate, Sodium ADA
Resolution 4.60 Å R-free 0.248
5LID X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromopromazine Deposited 2016-07-14 Assembly 1 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 11–316（306 aa）
Chain B 11–316（306 aa）
Chain C 11–316（306 aa）
Chain D 11–316（306 aa）
Chain E 11–316（306 aa）
Not recorded 6XY bromopromazine × 10 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；200 mM ammonium sulfate, 50 mM ADA pH 6.5, 9-12 % PEG4000
Resolution 4.50 Å R-free 0.257
5LID X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromopromazine Deposited 2016-07-14 Assembly 2 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain F 11–316（306 aa）
Chain G 11–316（306 aa）
Chain H 11–316（306 aa）
Chain I 11–316（306 aa）
Chain J 11–316（306 aa）
Not recorded 6XY bromopromazine × 10 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；200 mM ammonium sulfate, 50 mM ADA pH 6.5, 9-12 % PEG4000
Resolution 4.50 Å R-free 0.257
5SXV X-ray structure of 2-bromoethanol bound to a pentameric ligand gated ion channel (ELIC) in a resting state Deposited 2016-08-10 Assembly 1 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 1–321（321 aa）
Chain B 1–321（321 aa）
Chain C 1–321（321 aa）
Chain D 1–321（321 aa）
Chain E 1–321（321 aa）
Not recorded BRJ 2-BROMOETHANOL × 16 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.1；277 K；PEG 4000, ammonium sulfate
Resolution 3.40 Å R-free 0.259
5SXV X-ray structure of 2-bromoethanol bound to a pentameric ligand gated ion channel (ELIC) in a resting state Deposited 2016-08-10 Assembly 2 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain F 1–321（321 aa）
Chain G 1–321（321 aa）
Chain H 1–321（321 aa）
Chain I 1–321（321 aa）
Chain J 1–321（321 aa）
Not recorded BRJ 2-BROMOETHANOL × 16 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.1；277 K；PEG 4000, ammonium sulfate
Resolution 3.40 Å R-free 0.259
6HJX X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) 7'C pore mutant (L238C) in complex with nanobody 72 Deposited 2018-09-04 Assembly 1 Protein heterocomplex Heteromer；Protein × 10 PDB declaration: decameric（10） Consistent with protein count
Chain A 9–313（305 aa）
Chain B 8–313（306 aa）
Chain C 8–316（309 aa）
Chain D 9–317（309 aa）
Chain E 8–313（306 aa）
Mutation：C300S, C313S, L238C P6G HEXAETHYLENE GLYCOL × 4 PTY PHOSPHATIDYLETHANOLAMINE × 1 LMT DODECYL-BETA-D-MALTOSIDE × 5 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 1 NA SODIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；100 mM MES (pH 6.5) and 30% PEG400
Resolution 2.50 Å R-free 0.245
6HJY X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) Delta8 truncation mutant in complex with nanobody 72 Deposited 2018-09-04 Assembly 1 Protein heterocomplex Heteromer；Protein × 10 PDB declaration: decameric（10） Consistent with protein count
Chain A 9–284（276 aa）
Chain B 8–284（277 aa）
Chain C 8–284（277 aa）
Chain D 10–284（275 aa）
Chain E 8–284（277 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；300 mM ammonium formate, 50 mM TRIS pH 9.0 and 33% PEG monomethylether 550
Resolution 2.78 Å R-free 0.233
6HK0 X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) F16'S pore mutant (F247S) with alternate M4 conformation. Deposited 2018-09-04 Assembly 1 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 11–316（306 aa）
Chain B 11–316（306 aa）
Chain C 11–316（306 aa）
Chain D 11–316（306 aa）
Chain E 11–316（306 aa）
Not recorded LMT DODECYL-BETA-D-MALTOSIDE × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；200 mM ammonium sulfate, 50 mM ADA pH 6.5, 12% PEG4000
Resolution 3.45 Å R-free 0.266
6HK0 X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) F16'S pore mutant (F247S) with alternate M4 conformation. Deposited 2018-09-04 Assembly 2 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain F 11–316（306 aa）
Chain G 11–316（306 aa）
Chain H 11–316（306 aa）
Chain I 11–316（306 aa）
Chain J 11–316（306 aa）
Not recorded LMT DODECYL-BETA-D-MALTOSIDE × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；200 mM ammonium sulfate, 50 mM ADA pH 6.5, 12% PEG4000
Resolution 3.45 Å R-free 0.266
6SSI Structure of the pentameric ligand-gated ion channel ELIC in complex with a PAM nanobody Deposited 2019-09-07 Assembly 1 Protein heterocomplex Heteromer；Protein × 10 PDB declaration: decameric（10） Consistent with protein count
Chain A 8–320（313 aa）
Chain B 8–320（313 aa）
Chain C 8–320（313 aa）
Chain D 8–320（313 aa）
Chain E 8–320（313 aa）
Not recorded ABU GAMMA-AMINO-BUTANOIC ACID × 5 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 5 GOL GLYCEROL × 6 CA CALCIUM ION × 5 PG4 TETRAETHYLENE GLYCOL × 4 UMQ UNDECYL-MALTOSIDE × 5 ACT ACETATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；0.1 M GABA, 0.2 M Ca(OAc)2, 0.1 M MES buffer, 10% PEG8000
Resolution 2.59 Å R-free 0.246
6SSP Structure of the pentameric ligand-gated ion channel ELIC in complex with a NAM nanobody Deposited 2019-09-09 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 8–320（313 aa）
Chain B 8–320（313 aa）
Chain C 8–320（313 aa）
Chain D 8–320（313 aa）
Chain E 8–320（313 aa）
Not recorded CA CALCIUM ION × 4 UMQ UNDECYL-MALTOSIDE × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；293 K；0.1 M Na2SO4, 0.1 M bis-trispropane, 10% PEG3350
Resolution 3.25 Å R-free 0.264
6SSP Structure of the pentameric ligand-gated ion channel ELIC in complex with a NAM nanobody Deposited 2019-09-09 Assembly 2 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain F 8–320（313 aa）
Chain G 8–320（313 aa）
Chain H 8–320（313 aa）
Chain I 8–320（313 aa）
Chain J 8–320（313 aa）
Not recorded CA CALCIUM ION × 4 UMQ UNDECYL-MALTOSIDE × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；293 K；0.1 M Na2SO4, 0.1 M bis-trispropane, 10% PEG3350
Resolution 3.25 Å R-free 0.264
8VUW ELIC5 with cysteamine in 2:1:1 POPC:POPE:POPG nanodisc in open conformation Deposited 2024-01-29 Assembly 1 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 1–321（321 aa）
Chain B 1–321（321 aa）
Chain C 1–321（321 aa）
Chain D 1–321（321 aa）
Chain E 1–321（321 aa）
Mutation：P254G, V261Y, C300S, G319F, I320F Mutation：P254G, V261Y, C300S, G319F, I320F Mutation：P254G, V261Y, C300S, G319F, I320F Mutation：P254G, V261Y, C300S, G319F, I320F Mutation：P254G, V261Y, C300S, G319F, I320F PGW (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate × 5 DHL 2-AMINO-ETHANETHIOL × 5 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；Blot for 2 seconds before plunging
Resolution 3.19 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.