← Back to search

Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P10147 New Search
13PDB entries
31Biological assembly
62chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1B50 NMR STRUCTURE OF HUMAN MIP-1A D26A, 10 STRUCTURES Deposited 1999-01-11 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 24–92（69 aa）
Chain B 24–92（69 aa）
Mutation：D26A Mutation：D26A No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 3.5；318 K；Ionic strength (raw mmCIF value) NO ADDED SALT；Pressure 1
NMR sample composition 10% H2O/90% D2O
Resolution not provided
1B53 NMR STRUCTURE OF HUMAN MIP-1A D26A, MINIMIZED AVERAGE STRUCTURE Deposited 1999-01-11 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 24–92（69 aa）
Chain B 24–92（69 aa）
Mutation：D26A Mutation：D26A No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 3.5；318 K；Ionic strength (raw mmCIF value) NO ADDED SALT；Pressure 1
NMR sample composition 10% H2O/90% D2O
Resolution not provided
2X69 X-ray Structure of Macrophage Inflammatory Protein-1 alpha polymer Deposited 2010-02-15 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 23–92（70 aa） Fragment：RESIDUES 23-92
Chain C 23–92（70 aa） Fragment：RESIDUES 23-92
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.65 Å R-free 0.265
2X69 X-ray Structure of Macrophage Inflammatory Protein-1 alpha polymer Deposited 2010-02-15 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 23–92（70 aa） Fragment：RESIDUES 23-92
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.65 Å R-free 0.265
2X69 X-ray Structure of Macrophage Inflammatory Protein-1 alpha polymer Deposited 2010-02-15 Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain D 23–92（70 aa） Fragment：RESIDUES 23-92
Chain E 23–92（70 aa） Fragment：RESIDUES 23-92
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.65 Å R-free 0.265
2X6G X-ray Structure of Macrophage Inflammatory Protein-1 alpha (D27A) Deposited 2010-02-17 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain Q 23–92（70 aa）
Chain R 23–92（70 aa）
Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 0.2M NH4AC, 0.1M HEPES (PH7.8), 26% PEG3350
Resolution 2.18 Å R-free 0.286
2X6G X-ray Structure of Macrophage Inflammatory Protein-1 alpha (D27A) Deposited 2010-02-17 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain E 23–92（70 aa）
Chain F 23–92（70 aa）
Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 0.2M NH4AC, 0.1M HEPES (PH7.8), 26% PEG3350
Resolution 2.18 Å R-free 0.286
2X6G X-ray Structure of Macrophage Inflammatory Protein-1 alpha (D27A) Deposited 2010-02-17 Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain O 23–92（70 aa）
Chain P 23–92（70 aa）
Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 0.2M NH4AC, 0.1M HEPES (PH7.8), 26% PEG3350
Resolution 2.18 Å R-free 0.286
2X6G X-ray Structure of Macrophage Inflammatory Protein-1 alpha (D27A) Deposited 2010-02-17 Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 23–92（70 aa）
Chain D 23–92（70 aa）
Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 0.2M NH4AC, 0.1M HEPES (PH7.8), 26% PEG3350
Resolution 2.18 Å R-free 0.286
2X6G X-ray Structure of Macrophage Inflammatory Protein-1 alpha (D27A) Deposited 2010-02-17 Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain I 23–92（70 aa）
Chain J 23–92（70 aa）
Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 0.2M NH4AC, 0.1M HEPES (PH7.8), 26% PEG3350
Resolution 2.18 Å R-free 0.286
2X6G X-ray Structure of Macrophage Inflammatory Protein-1 alpha (D27A) Deposited 2010-02-17 Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 23–92（70 aa）
Chain B 23–92（70 aa）
Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 0.2M NH4AC, 0.1M HEPES (PH7.8), 26% PEG3350
Resolution 2.18 Å R-free 0.286
2X6G X-ray Structure of Macrophage Inflammatory Protein-1 alpha (D27A) Deposited 2010-02-17 Assembly 7 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain G 23–92（70 aa）
Chain H 23–92（70 aa）
Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 0.2M NH4AC, 0.1M HEPES (PH7.8), 26% PEG3350
Resolution 2.18 Å R-free 0.286
2X6G X-ray Structure of Macrophage Inflammatory Protein-1 alpha (D27A) Deposited 2010-02-17 Assembly 8 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain M 23–92（70 aa）
Chain N 23–92（70 aa）
Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 0.2M NH4AC, 0.1M HEPES (PH7.8), 26% PEG3350
Resolution 2.18 Å R-free 0.286
2X6G X-ray Structure of Macrophage Inflammatory Protein-1 alpha (D27A) Deposited 2010-02-17 Assembly 9 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain K 23–92（70 aa）
Chain L 23–92（70 aa）
Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 0.2M NH4AC, 0.1M HEPES (PH7.8), 26% PEG3350
Resolution 2.18 Å R-free 0.286
3FPU The crystallographic structure of the Complex between Evasin-1 and CCL3 Deposited 2009-01-06 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 24–92（69 aa）
Mutation：A10T NI NICKEL (II) ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.1；291 K；24% (w/v) PEG 3350, 200mM Ammonium sulfate, 100mM HEPES, pH 8.1, VAPOR DIFFUSION, SITTING DROP, temperature 291K
Resolution 1.76 Å R-free 0.285
3H44 Crystal Structure of Insulin Degrading Enzyme in Complex with macrophage inflammatory protein 1 alpha Deposited 2009-04-17 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain C 23–92（70 aa） Fragment：residues 23-92
Chain D 23–92（70 aa） Fragment：residues 23-92
Not recorded DIO 1,4-DIETHYLENE DIOXIDE × 6 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；291 K；13% PEGMME 5000, 100mM HEPES, pH 7.0, 10%, Tacsimate, 10% dioxane, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 3.00 Å R-free 0.237
3H44 Crystal Structure of Insulin Degrading Enzyme in Complex with macrophage inflammatory protein 1 alpha Deposited 2009-04-17 Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain C 23–92（70 aa） Fragment：residues 23-92
Chain D 23–92（70 aa） Fragment：residues 23-92
Not recorded DIO 1,4-DIETHYLENE DIOXIDE × 6 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；291 K；13% PEGMME 5000, 100mM HEPES, pH 7.0, 10%, Tacsimate, 10% dioxane, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 3.00 Å R-free 0.237
3H44 Crystal Structure of Insulin Degrading Enzyme in Complex with macrophage inflammatory protein 1 alpha Deposited 2009-04-17 Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 23–92（70 aa） Fragment：residues 23-92
Not recorded DIO 1,4-DIETHYLENE DIOXIDE × 3 ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；291 K；13% PEGMME 5000, 100mM HEPES, pH 7.0, 10%, Tacsimate, 10% dioxane, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 3.00 Å R-free 0.237
3H44 Crystal Structure of Insulin Degrading Enzyme in Complex with macrophage inflammatory protein 1 alpha Deposited 2009-04-17 Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain D 23–92（70 aa） Fragment：residues 23-92
Not recorded DIO 1,4-DIETHYLENE DIOXIDE × 3 ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；291 K；13% PEGMME 5000, 100mM HEPES, pH 7.0, 10%, Tacsimate, 10% dioxane, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 3.00 Å R-free 0.237
3KBX Human macrophage inflammatory protein-1 alpha L3M_V63M Deposited 2009-10-20 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 23–92（70 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) K POTASSIUM ION × 2 ACT ACETATE ION × 2 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.65 Å R-free 0.257
3KBX Human macrophage inflammatory protein-1 alpha L3M_V63M Deposited 2009-10-20 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 23–92（70 aa）
Chain C 23–92（70 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.65 Å R-free 0.257
3KBX Human macrophage inflammatory protein-1 alpha L3M_V63M Deposited 2009-10-20 Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain D 23–92（70 aa）
Chain E 23–92（70 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.65 Å R-free 0.257
4RA8 Structure analysis of the Mip1a P8A mutant Deposited 2014-09-09 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 23–91（69 aa） Fragment：UNP residues 23-91
Mutation：P8A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；0.1 M Bis-Tris, pH 5.5, 2 M ammonium sulfate, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.60 Å R-free 0.248
4RA8 Structure analysis of the Mip1a P8A mutant Deposited 2014-09-09 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 23–91（69 aa） Fragment：UNP residues 23-91
Chain C 23–91（69 aa） Fragment：UNP residues 23-91
Mutation：P8A Mutation：P8A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；0.1 M Bis-Tris, pH 5.5, 2 M ammonium sulfate, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.60 Å R-free 0.248
4RA8 Structure analysis of the Mip1a P8A mutant Deposited 2014-09-09 Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain D 23–91（69 aa） Fragment：UNP residues 23-91
Chain E 23–91（69 aa） Fragment：UNP residues 23-91
Mutation：P8A Mutation：P8A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；0.1 M Bis-Tris, pH 5.5, 2 M ammonium sulfate, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.60 Å R-free 0.248
4ZKB The chemokine binding protein of orf virus complexed with CCL3 Deposited 2015-04-30 Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 24–92（69 aa） Fragment：UNP residues 24-92
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；289 K；0.2M potassium sodium tartrate tetrahydrate, 0.1M sodium citrate tribasic dihydrate pH5.6, 2.0M ammonium citrate
Resolution 2.90 Å R-free 0.323
5COR X-RAY STRUCTURE OF MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA (CCL3) N-TERMINAL-SWITCH POLYMER Deposited 2015-07-20 Assembly 1 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 23–92（70 aa）
Chain C 23–92（70 aa）
Chain E 23–92（70 aa）
Chain G 23–92（70 aa）
Chain I 23–92（70 aa）
Not recorded HEZ HEXANE-1,6-DIOL × 6 ACT ACETATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291.16 K；0.01 M Cobalt (II) chloride hexahydrate, 0.1 M Sodium acetate trihydrate pH 4.6, 1.0 M 1,6-Hexanediol
Resolution 2.55 Å R-free 0.220
5COR X-RAY STRUCTURE OF MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA (CCL3) N-TERMINAL-SWITCH POLYMER Deposited 2015-07-20 Assembly 2 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain B 23–92（70 aa）
Chain D 23–92（70 aa）
Chain F 23–92（70 aa）
Chain H 23–92（70 aa）
Chain J 23–92（70 aa）
Not recorded HEZ HEXANE-1,6-DIOL × 4 ACT ACETATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291.16 K；0.01 M Cobalt (II) chloride hexahydrate, 0.1 M Sodium acetate trihydrate pH 4.6, 1.0 M 1,6-Hexanediol
Resolution 2.55 Å R-free 0.220
5D65 X-RAY STRUCTURE OF MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA (CCL3) WITH HEPARIN COMPLEX Deposited 2015-08-11 Assembly 1 Other combination Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 23–92（70 aa） Fragment：UNP residues 23-92
Chain B 23–92（70 aa） Fragment：UNP residues 23-92
Chain C 23–92（70 aa） Fragment：UNP residues 23-92
Chain D 23–92（70 aa） Fragment：UNP residues 23-92
Chain E 23–92（70 aa） Fragment：UNP residues 23-92
Not recorded BGC beta-D-glucopyranose × 9 CL CHLORIDE ION × 2 GLC alpha-D-glucopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；291.15 K；0.1M Tris, pH 7.0; 1.8M (NH4)2SO4;
Resolution 3.10 Å R-free 0.243
7F1Q Cryo-EM structure of the chemokine receptor CCR5 in complex with MIP-1a and Gi Deposited 2021-06-09 Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain R 24–92（69 aa）
Mutation：T15R,T112C,G259N No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.90 Å
7F1T Crystal structure of the human chemokine receptor CCR5 in complex with MIP-1a Deposited 2021-06-09 Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 24–92（69 aa）
Mutation：T15C,T108C,C150Y,M156A,G255N,A376D,R417A,T427A,K446E ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions LIPIDIC CUBIC PHASE；293 K；100mM HEPES, pH 6.0, 250mM ammonium sulfate, 30% (v/v) PEG 400, 8% (v/v) PPG 400
Resolution 2.60 Å R-free 0.271

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.