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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P13501 New Search
23PDB entries
26Biological assembly
84chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1B3A TOTAL CHEMICAL SYNTHESIS AND HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE POTENT ANTI-HIV PROTEIN AOP-RANTES Deposited 1998-12-07 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 10–76（67 aa）
Not recorded SO4 SULFATE ION × 3 AOP PENTYLOXYAMINO-ACETALDEHYDE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.6；pH 4.6
Resolution 1.60 Å R-free 0.241
1B3A TOTAL CHEMICAL SYNTHESIS AND HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE POTENT ANTI-HIV PROTEIN AOP-RANTES Deposited 1998-12-07 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 10–76（67 aa）
Not recorded SO4 SULFATE ION × 1 AOP PENTYLOXYAMINO-ACETALDEHYDE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.6；pH 4.6
Resolution 1.60 Å R-free 0.241
1EQT MET-RANTES Deposited 2000-04-06 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 25–91（67 aa）
Chain B 25–91（67 aa）
Not recorded SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.6；295 K；PEG 35000, ammonium sulfate, sodium succinate, MES, sodium acetate, ethanol, pH 4.6, VAPOR DIFFUSION, HANGING DROP, temperature 295.0K
Resolution 1.60 Å R-free 0.251
1HRJ HUMAN RANTES, NMR, 13 STRUCTURES Deposited 1995-08-18 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 24–91（68 aa）
Chain B 24–91（68 aa）
Not recorded No recorded non-water small molecule SOLUTION NMR mmCIF provides none of the parsed conditions Resolution not provided
1RTN PROTON NMR ASSIGNMENTS AND SOLUTION CONFORMATION OF RANTES, A CHEMOKINE OF THE CC TYPE Deposited 1995-02-21 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 24–91（68 aa）
Chain B 24–91（68 aa）
Not recorded No recorded non-water small molecule SOLUTION NMR mmCIF provides none of the parsed conditions Resolution not provided
1RTO PROTON NMR ASSIGNMENTS AND SOLUTION CONFORMATION OF RANTES, A CHEMOKINE OF THE CC TYPE Deposited 1995-02-21 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 24–91（68 aa）
Chain B 24–91（68 aa）
Not recorded No recorded non-water small molecule SOLUTION NMR mmCIF provides none of the parsed conditions Resolution not provided
1U4L human RANTES complexed to heparin-derived disaccharide I-S Deposited 2004-07-26 Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 24–91（68 aa）
Chain B 24–91（68 aa）
Not recorded ACY ACETIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.5；293 K；15% (w/v) PEG 400, 100mM acetate buffer, 1mM Heparin Disaccharide I-S, 10% (w/v) glycerol, pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.00 Å R-free 0.255
1U4M human RANTES complexed to heparin-derived disaccharide III-S Deposited 2004-07-26 Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 24–91（68 aa）
Chain B 24–91（68 aa）
Not recorded ACY ACETIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.5；293 K；15% (w/v) PEG 400, 100mM acetate buffer, 1mM Heparin Disaccharide III-S, 10% (w/v) glycerol, pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.00 Å R-free 0.252
1U4P Crystal Structure of human RANTES mutant K45E Deposited 2004-07-26 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 24–91（68 aa）
Chain B 24–91（68 aa）
Mutation：K45E Mutation：K45E ACY ACETIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.5；293 K；20% PEG 400, 100mM acetate buffer, pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 1.70 Å R-free 0.254
1U4R Crystal Structure of human RANTES mutant 44-AANA-47 Deposited 2004-07-26 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 24–91（68 aa）
Chain B 24–91（68 aa）
Mutation：R44A, K45A, R47A Mutation：R44A, K45A, R47A SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.5；293 K；25% PEG 400, 100mM acetate buffer, 200mM (NH4)2SO4, 10% (v/v) glycerol, pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.20 Å R-free 0.306
1U4R Crystal Structure of human RANTES mutant 44-AANA-47 Deposited 2004-07-26 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 24–91（68 aa）
Chain D 24–91（68 aa）
Mutation：R44A, K45A, R47A Mutation：R44A, K45A, R47A SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.5；293 K；25% PEG 400, 100mM acetate buffer, 200mM (NH4)2SO4, 10% (v/v) glycerol, pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.20 Å R-free 0.306
2L9H Oligomeric Structure of the Chemokine CCL5/RANTES from NMR, MS, and SAXS Data Deposited 2011-02-09 Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 24–91（68 aa）
Chain B 24–91（68 aa）
Chain C 24–91（68 aa）
Chain D 24–91（68 aa）
Not recorded No recorded non-water small molecule Not declared
NMR measurement conditions pH 4.4；297 K；Ionic strength (raw mmCIF value) 0.05；Pressure ambient
NMR sample composition 1 mM [U-100% 15N] ccl5, 50 mM sodium acetate, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition 1 mM [U-100% 15N] ccl5, 50 mM sodium acetate, 5 % polyacrylamide, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2VXW Structural and Functional Studies of the Potent Anti-HIV Chemokine Variant P2-RANTES Deposited 2008-07-12 Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 33–91（59 aa） Fragment：CHEMOKINE, RESIDUES 33-91
Chain B 33–91（59 aa） Fragment：CHEMOKINE, RESIDUES 33-91
Chain C 33–91（59 aa） Fragment：CHEMOKINE, RESIDUES 33-91
Chain D 33–91（59 aa） Fragment：CHEMOKINE, RESIDUES 33-91
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 1.70 Å R-free 0.248
5CMD Oligomer crystal structure of CC chemokine 5 (CCL5) Deposited 2015-07-16 Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 27–91（65 aa） Fragment：unp residues 27-91
Chain B 27–91（65 aa） Fragment：unp residues 27-91
Chain C 27–91（65 aa） Fragment：unp residues 27-91
Chain D 27–91（65 aa） Fragment：unp residues 27-91
Chain E 27–91（65 aa） Fragment：unp residues 27-91
Chain F 27–91（65 aa） Fragment：unp residues 27-91
Not recorded SO4 SULFATE ION × 11 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；303.15 K；0.1 M Tris, 1.8 M Ammonium sulfate
Resolution 3.09 Å R-free 0.258
5COY Crystal structure of CC chemokine 5 (CCL5) Deposited 2015-07-20 Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 27–91（65 aa）
Chain B 27–91（65 aa）
Not recorded PO4 PHOSPHATE ION × 2 PEG DI(HYDROXYETHYL)ETHER × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291.15 K；0.2 M Potassium phosphate monobasic, 20% w/v Polyethylene glycol 3,350
Resolution 1.44 Å R-free 0.192
5DNF Crystal structure of CC chemokine 5 (CCL5) oligomer in complex with heparin Deposited 2015-09-10 Assembly 1 Other combination Homooligomer；Protein × 9 PDB declaration: nonameric（9） Consistent with protein count
Chain A 27–91（65 aa） Fragment：UNP residues 27-91
Chain B 27–91（65 aa） Fragment：UNP residues 27-91
Chain C 27–91（65 aa） Fragment：UNP residues 27-91
Chain D 27–91（65 aa） Fragment：UNP residues 27-91
Chain E 27–91（65 aa） Fragment：UNP residues 27-91
Chain F 27–91（65 aa） Fragment：UNP residues 27-91
Chain G 27–91（65 aa） Fragment：UNP residues 27-91
Chain H 27–91（65 aa） Fragment：UNP residues 27-91
Chain I 27–91（65 aa） Fragment：UNP residues 27-91
Mutation：S4TNR Mutation：S4TNR Mutation：S4TNR Mutation：S4TNR Mutation：S4TNR Mutation：S4TNR Mutation：S4TNR Mutation：S4TNR Mutation：S4TNR GLA alpha-D-galactopyranose × 6 BGC beta-D-glucopyranose × 5 SO4 SULFATE ION × 5 CL CHLORIDE ION × 20 TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；303.15 K；0.1M Tris, pH 7.5; 1.8 M (NH4)2SO4
Resolution 2.55 Å R-free 0.234
5L2U Oligomer crystal structure of CC chemokine 5 (CCL5) Deposited 2016-08-02 Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 27–91（65 aa） Fragment：UNP residues 27-91
Chain B 27–91（65 aa） Fragment：UNP residues 27-91
Chain C 27–91（65 aa） Fragment：UNP residues 27-91
Chain D 27–91（65 aa） Fragment：UNP residues 27-91
Chain E 27–91（65 aa） Fragment：UNP residues 27-91
Chain F 27–91（65 aa） Fragment：UNP residues 27-91
Not recorded EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 2 CL CHLORIDE ION × 2 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.8；303.15 K；0.1 HEPES, 300 mM NaCl, 3.5% 2-propanol
Resolution 2.28 Å R-free 0.209
5L2U Oligomer crystal structure of CC chemokine 5 (CCL5) Deposited 2016-08-02 Assembly 2 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain G 27–91（65 aa） Fragment：UNP residues 27-91
Chain H 27–91（65 aa） Fragment：UNP residues 27-91
Chain I 27–91（65 aa） Fragment：UNP residues 27-91
Not recorded EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.8；303.15 K；0.1 HEPES, 300 mM NaCl, 3.5% 2-propanol
Resolution 2.28 Å R-free 0.209
5UIW Crystal Structure of CC Chemokine Receptor 5 (CCR5) in complex with high potency HIV entry inhibitor 5P7-CCL5 Deposited 2017-01-15 Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 33–91（59 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ZN ZINC ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 6 OLA OLEIC ACID × 2 X-RAY DIFFRACTION
X-ray crystallization conditions LIPIDIC CUBIC PHASE；pH 6.3；295.5 K；29% (v/v) PEG 400, 120 mM lithium citrate, 1.2% (w/v) 1,5-Diaminopentane dihydrochloride, 100 mM 2-(N-morpholino)ethanesulfonic acid
Resolution 2.20 Å R-free 0.250
6AEZ Crystal structure of human CCL5 trimer Deposited 2018-08-07 Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 24–91（68 aa）
Chain B 24–91（68 aa）
Chain C 24–91（68 aa）
Mutation：E67S Mutation：E67S SO4 SULFATE ION × 12 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；283 K；0.2M ammonium sulfate, 0.1M BIS-TRIS pH 5, 16% (w/v) polyethylene glycol 3350
Resolution 1.63 Å R-free 0.228
6C6D 20mer crystal structure of CC chemokine 5 (CCL5) Deposited 2018-01-18 Assembly 1 Protein homooligomer Homooligomer；Protein × 20 PDB declaration: eicosameric（20） Consistent with protein count
Chain A 27–91（65 aa） Fragment：UNP Residues 27-91
Chain B 27–91（65 aa） Fragment：UNP Residues 27-91
Chain C 27–91（65 aa） Fragment：UNP Residues 27-91
Chain D 27–91（65 aa） Fragment：UNP Residues 27-91
Chain E 27–91（65 aa） Fragment：UNP Residues 27-91
Chain F 27–91（65 aa） Fragment：UNP Residues 27-91
Chain G 27–91（65 aa） Fragment：UNP Residues 27-91
Chain H 27–91（65 aa） Fragment：UNP Residues 27-91
Chain I 27–91（65 aa） Fragment：UNP Residues 27-91
Chain J 27–91（65 aa） Fragment：UNP Residues 27-91
Chain K 27–91（65 aa） Fragment：UNP Residues 27-91
Chain L 27–91（65 aa） Fragment：UNP Residues 27-91
Chain M 27–91（65 aa） Fragment：UNP Residues 27-91
Chain N 27–91（65 aa） Fragment：UNP Residues 27-91
Chain O 27–91（65 aa） Fragment：UNP Residues 27-91
Chain P 27–91（65 aa） Fragment：UNP Residues 27-91
Chain Q 27–91（65 aa） Fragment：UNP Residues 27-91
Chain R 27–91（65 aa） Fragment：UNP Residues 27-91
Chain S 27–91（65 aa） Fragment：UNP Residues 27-91
Chain T 27–91（65 aa） Fragment：UNP Residues 27-91
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；303.15 K；10% (v/v) 2-propanol, 0.1M HEPES pH 7.5, 0.2M NaCl
Resolution 5.50 Å R-free 0.286
6FGP NMR solution structure of monomeric CCL5 in complex with a doubly-sulfated N-terminal segment of CCR5 Deposited 2018-01-11 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 24–91（68 aa）
Mutation：i No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 4.8；310 K；Ionic strength (raw mmCIF value) 130；Pressure 1
NMR measurement conditions pH 4.8；310 K；Ionic strength (raw mmCIF value) 130；Pressure 1
NMR measurement conditions pH 4.8；310 K；Ionic strength (raw mmCIF value) 130；Pressure 1
NMR sample composition 120 uM [U-15N] CCL5(P9S)/Nt-CCR5(1-27), 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition 120 uM [U-13C] CCL5(P9S)/Nt-CCR5(1-27), 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition 120 uM U-15N;13C CCL5(P9S)/Nt-CCR5(1-27), 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
6LOG Crystal structure of human CCL5-12AAA14 mutant Deposited 2020-01-05 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 24–91（68 aa）
Mutation：F12A, Y14A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.9；283 K；0.2M Magnesium acetate tetrahydrate pH 7.9, 20% PEG 3350
Resolution 2.55 Å R-free 0.249
6STK Crystal structure of the CC-chemokine 5 (CCL5) E66S mutation Deposited 2019-09-10 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 24–91（68 aa）
Chain B 24–91（68 aa）
Mutation：E66S Mutation：E66S ACT ACETATE ION × 1 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291 K；15% glycerol, 25.5% PEG 4000, 85mM acetate buffer pH 4.6, 0.17 M ammonium acetate
Resolution 1.52 Å R-free 0.203
7F1R Cryo-EM structure of the chemokine receptor CCR5 in complex with RANTES and Gi Deposited 2021-06-09 Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain R 24–91（68 aa）
Mutation：F28C,G258N,E267C No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.00 Å
7O7F Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist Deposited 2021-04-13 Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric（7） Consistent with protein count
Chain I 23–91（69 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.15 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.