Current Protein Identity:P17763
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 3L6P Crystal Structure of Dengue Virus 1 NS2B/NS3 protease Deposited 2009-12-23 | Assembly 1 Insufficient information Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1476–1661(186 aa)
Fragment:NS2B residues 1394-1440, NS3 PROTEASE residues 1476-1661
|
Mutation:deletion NS3 PROTEASE, residues 1486-1495 | NI NICKEL (II) ION × 6 CD CADMIUM ION × 2 SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.5;293 K;0.1M HEPES pH 7.5, 12% PEG 3350 and 0.005M each of NiCl2, CdCl2, MgCl2 and CoCl2, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.20 Å R-free 0.284 |
| 3L6P Crystal Structure of Dengue Virus 1 NS2B/NS3 protease Deposited 2009-12-23 | Assembly 2 Insufficient information Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
1476–1661(186 aa)
Fragment:NS2B residues 1394-1440, NS3 PROTEASE residues 1476-1661
|
Mutation:deletion NS3 PROTEASE, residues 1486-1495 | NI NICKEL (II) ION × 12 CD CADMIUM ION × 4 SO4 SULFATE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.5;293 K;0.1M HEPES pH 7.5, 12% PEG 3350 and 0.005M each of NiCl2, CdCl2, MgCl2 and CoCl2, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.20 Å R-free 0.284 |
| 3LKW Crystal Structure of Dengue Virus 1 NS2B/NS3 protease active site mutant Deposited 2010-01-28 | Assembly 1 Insufficient information Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1476–1661(186 aa)
Fragment:NS2B residues 1394-1440, NS3 PROTEASE residues 1476-1661
|
Mutation:deletion NS3 PROTEASE, residues 1486-1495 | CL CHLORIDE ION × 2 CD CADMIUM ION × 2 SO4 SULFATE ION × 2 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.5;293 K;0.1M Hepes pH 7.5, 12% PEG 3350, 0.005M each NiCl2, CdCl2, MgCl2, CoCl2, 0.1M Potassium sodium tartrate tetrahydrate, vapor diffusion, temperature 293K
|
Resolution 2.00 Å R-free 0.249 |
| 3LKW Crystal Structure of Dengue Virus 1 NS2B/NS3 protease active site mutant Deposited 2010-01-28 | Assembly 2 Insufficient information Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
1476–1661(186 aa)
Fragment:NS2B residues 1394-1440, NS3 PROTEASE residues 1476-1661
|
Mutation:deletion NS3 PROTEASE, residues 1486-1495 | CL CHLORIDE ION × 4 CD CADMIUM ION × 4 SO4 SULFATE ION × 4 GOL GLYCEROL × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.5;293 K;0.1M Hepes pH 7.5, 12% PEG 3350, 0.005M each NiCl2, CdCl2, MgCl2, CoCl2, 0.1M Potassium sodium tartrate tetrahydrate, vapor diffusion, temperature 293K
|
Resolution 2.00 Å R-free 0.249 |
| 4FFZ Crystal Structure of DENV1-E111 fab fragment bound to DENV-1 DIII (Western Pacific-74 strain). Deposited 2012-06-01 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain A
573–679(107 aa)
Fragment:UNP residues 573-679
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6;293 K;20% PEG 6000, 0.1M MES, 1% glycerol., pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 3.80 Å R-free 0.278 |
| 4FFZ Crystal Structure of DENV1-E111 fab fragment bound to DENV-1 DIII (Western Pacific-74 strain). Deposited 2012-06-01 | Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain X
573–679(107 aa)
Fragment:UNP residues 573-679
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6;293 K;20% PEG 6000, 0.1M MES, 1% glycerol., pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 3.80 Å R-free 0.278 |
| 4GSX High resolution structure of dengue virus serotype 1 sE containing stem Deposited 2012-08-28 | Assembly 1 Protein homooligomer Homooligomer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain A
281–691(411 aa)
Fragment:UNP residues 281-691
|
Mutation:W101H | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 CD CADMIUM ION × 6 CL CHLORIDE ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 4.5;293 K;pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.90 Å R-free 0.186 |
| 4GSX High resolution structure of dengue virus serotype 1 sE containing stem Deposited 2012-08-28 | Assembly 2 Protein homooligomer Homooligomer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain B
281–691(411 aa)
Fragment:UNP residues 281-691
|
Mutation:W101H | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 CD CADMIUM ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 4.5;293 K;pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.90 Å R-free 0.186 |
| 4GT0 Structure of dengue virus serotype 1 sE containing stem to residue 421 Deposited 2012-08-28 | Assembly 1 Protein homooligomer Homooligomer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain A
281–701(421 aa)
Fragment:sE(421), UNP residues 281-701
|
Mutation:W101H | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 CD CADMIUM ION × 6 CL CHLORIDE ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 4.5;293 K;pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.57 Å R-free 0.210 |
| 4GT0 Structure of dengue virus serotype 1 sE containing stem to residue 421 Deposited 2012-08-28 | Assembly 2 Protein homooligomer Homooligomer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain B
281–701(421 aa)
Fragment:sE(421), UNP residues 281-701
|
Mutation:W101H | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 CD CADMIUM ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 4.5;293 K;pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.57 Å R-free 0.210 |
| 4OIG Dengue Virus Non-structural Protein NS1 Deposited 2014-01-19 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
947–1127(181 aa)
Fragment:UNP residues 947-1127
Chain B
947–1127(181 aa)
Fragment:UNP residues 947-1127
|
Non-standard monomer:Yes (specific site not provided by mmCIF) Non-standard monomer:Yes (specific site not provided by mmCIF) | SO4 SULFATE ION × 8 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;293 K;12mg/mL in 20% PEG 4K, 0.2 M magnesium sulfate, 10% glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.69 Å R-free 0.268 |
| 4OIG Dengue Virus Non-structural Protein NS1 Deposited 2014-01-19 | Assembly 2 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain D
947–1127(181 aa)
Fragment:UNP residues 947-1127
Chain E
947–1127(181 aa)
Fragment:UNP residues 947-1127
|
Non-standard monomer:Yes (specific site not provided by mmCIF) Non-standard monomer:Yes (specific site not provided by mmCIF) | SO4 SULFATE ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;293 K;12mg/mL in 20% PEG 4K, 0.2 M magnesium sulfate, 10% glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.69 Å R-free 0.268 |
| 5VIC Crystal structure of anti-Zika antibody Z004 bound to DENV-1 Envelope protein DIII Deposited 2017-04-14 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain E
578–676(99 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4.5;295 K;0.1M sodium acetate trihydrate pH 4.5, 30% w/v PEG 1500
|
Resolution 3.00 Å R-free 0.286 |
| 8VPR Crystal structure of mouse Importin alpha in complex with Dengue 1 NS5 central NLS peptide Deposited 2024-01-16 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
2875–2890(16 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;296 K;0.75 M sodium citrate, 0.1 M HEPES
|
Resolution 2.70 Å R-free 0.242 |