Current Protein Identity:P20035 New Search
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1CJB MALARIAL PURINE PHOSPHORIBOSYLTRANSFERASE Deposited 1999-04-08 Assembly 1 Protein homooligomer Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count
Chain A 1–231(231 aa)
Chain B 1–231(231 aa)
Not recorded MG MAGNESIUM ION × 8 IRP (1S)-1(9-DEAZAHYPOXANTHIN-9YL)1,4-DIDEOXY-1,4-IMINO-D-RIBITOL-5-PHOSPHATE × 4 POP PYROPHOSPHATE 2- × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5;pH 7.5
Resolution 2.00 Å R-free 0.239
1CJB MALARIAL PURINE PHOSPHORIBOSYLTRANSFERASE Deposited 1999-04-08 Assembly 2 Protein homooligomer Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count
Chain C 1–231(231 aa)
Chain D 1–221(221 aa)
Not recorded MG MAGNESIUM ION × 8 IRP (1S)-1(9-DEAZAHYPOXANTHIN-9YL)1,4-DIDEOXY-1,4-IMINO-D-RIBITOL-5-PHOSPHATE × 4 POP PYROPHOSPHATE 2- × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5;pH 7.5
Resolution 2.00 Å R-free 0.239
2VFA Crystal structure of a chimera of Plasmodium falciparum and human hypoxanthine-guanine phosphoribosyl transferases Deposited 2007-11-02 Assembly 1 Insufficient information Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 1–56(56 aa) Fragment:RESIDUES 1-56,49-160,171-231
Chain A 171–231(61 aa) Fragment:RESIDUES 1-56,49-160,171-231
Chain B 1–56(56 aa) Fragment:RESIDUES 1-56,49-160,171-231
Chain B 171–231(61 aa) Fragment:RESIDUES 1-56,49-160,171-231
Not recorded 5GP GUANOSINE-5'-MONOPHOSPHATE × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8;0.1M TRIS PH 8.0, 2.0M AMMONIUM SULPHATE
Resolution 2.80 Å R-free 0.278
3OZF Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with hypoxanthine Deposited 2010-09-24 Assembly 1 Protein homooligomer Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count
Chain A 1–231(231 aa)
Chain B 1–231(231 aa)
Chain C 1–231(231 aa)
Chain D 1–231(231 aa)
Not recorded HPA HYPOXANTHINE × 4 POP PYROPHOSPHATE 2- × 4 PO4 PHOSPHATE ION × 4 MG MAGNESIUM ION × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7.4;291 K;200mM sodium citrate, 20% PEG3350, pH 7.4, vapor diffusion, sitting drop, temperature 291K
Resolution 1.94 Å R-free 0.237
3OZG Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with S-SerMe-ImmH phosphonate Deposited 2010-09-24 Assembly 1 Protein homooligomer Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count
Chain A 1–231(231 aa)
Chain B 1–231(231 aa)
Not recorded SSI [(3S)-4-hydroxy-3-{[(4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}butyl]phosphonic acid × 4 POP PYROPHOSPHATE 2- × 4 MG MAGNESIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7.4;291 K;200mM sodium citrate, 20% PEG3350, pH 7.4, vapor diffusion, sitting drop, temperature 291K
Resolution 1.99 Å R-free 0.264
3OZG Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with S-SerMe-ImmH phosphonate Deposited 2010-09-24 Assembly 2 Protein homooligomer Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count
Chain C 1–231(231 aa)
Chain D 1–231(231 aa)
Not recorded SSI [(3S)-4-hydroxy-3-{[(4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}butyl]phosphonic acid × 4 POP PYROPHOSPHATE 2- × 4 MG MAGNESIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7.4;291 K;200mM sodium citrate, 20% PEG3350, pH 7.4, vapor diffusion, sitting drop, temperature 291K
Resolution 1.99 Å R-free 0.264
7TUX Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with [(3S)-4-Hydroxy-3-[({2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl}methyl)amino]butyl]phosphonic acid Deposited 2022-02-03 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 1–231(231 aa)
Not recorded YBM [(3S)-3-{[(2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}-4-hydroxybutyl]phosphonic acid × 1 POP PYROPHOSPHATE 2- × 1 MG MAGNESIUM ION × 1 EDO 1,2-ETHANEDIOL × 9 ACY ACETIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;295 K;200 mM Lithium Acetate, 20% PEG3350
Resolution 1.62 Å R-free 0.195
7TUX Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with [(3S)-4-Hydroxy-3-[({2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl}methyl)amino]butyl]phosphonic acid Deposited 2022-02-03 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 1–231(231 aa)
Not recorded YBM [(3S)-3-{[(2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}-4-hydroxybutyl]phosphonic acid × 1 POP PYROPHOSPHATE 2- × 1 MG MAGNESIUM ION × 1 EDO 1,2-ETHANEDIOL × 12 ACY ACETIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;295 K;200 mM Lithium Acetate, 20% PEG3350
Resolution 1.62 Å R-free 0.195
7TUX Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with [(3S)-4-Hydroxy-3-[({2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl}methyl)amino]butyl]phosphonic acid Deposited 2022-02-03 Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain C 1–231(231 aa)
Not recorded YBM [(3S)-3-{[(2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}-4-hydroxybutyl]phosphonic acid × 1 POP PYROPHOSPHATE 2- × 1 MG MAGNESIUM ION × 1 EDO 1,2-ETHANEDIOL × 10 ACY ACETIC ACID × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;295 K;200 mM Lithium Acetate, 20% PEG3350
Resolution 1.62 Å R-free 0.195
7TUX Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with [(3S)-4-Hydroxy-3-[({2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl}methyl)amino]butyl]phosphonic acid Deposited 2022-02-03 Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain D 1–231(231 aa)
Not recorded YBM [(3S)-3-{[(2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}-4-hydroxybutyl]phosphonic acid × 1 POP PYROPHOSPHATE 2- × 1 MG MAGNESIUM ION × 1 EDO 1,2-ETHANEDIOL × 5 ACY ACETIC ACID × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;295 K;200 mM Lithium Acetate, 20% PEG3350
Resolution 1.62 Å R-free 0.195