Current Protein Identity:P20035
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1CJB MALARIAL PURINE PHOSPHORIBOSYLTRANSFERASE Deposited 1999-04-08 | Assembly 1 Protein homooligomer Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
1–231(231 aa)
Chain B
1–231(231 aa)
|
Not recorded | MG MAGNESIUM ION × 8 IRP (1S)-1(9-DEAZAHYPOXANTHIN-9YL)1,4-DIDEOXY-1,4-IMINO-D-RIBITOL-5-PHOSPHATE × 4 POP PYROPHOSPHATE 2- × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.5;pH 7.5
|
Resolution 2.00 Å R-free 0.239 |
| 1CJB MALARIAL PURINE PHOSPHORIBOSYLTRANSFERASE Deposited 1999-04-08 | Assembly 2 Protein homooligomer Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain C
1–231(231 aa)
Chain D
1–221(221 aa)
|
Not recorded | MG MAGNESIUM ION × 8 IRP (1S)-1(9-DEAZAHYPOXANTHIN-9YL)1,4-DIDEOXY-1,4-IMINO-D-RIBITOL-5-PHOSPHATE × 4 POP PYROPHOSPHATE 2- × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.5;pH 7.5
|
Resolution 2.00 Å R-free 0.239 |
| 2VFA Crystal structure of a chimera of Plasmodium falciparum and human hypoxanthine-guanine phosphoribosyl transferases Deposited 2007-11-02 | Assembly 1 Insufficient information Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–56(56 aa)
Fragment:RESIDUES 1-56,49-160,171-231
Chain A
171–231(61 aa)
Fragment:RESIDUES 1-56,49-160,171-231
Chain B
1–56(56 aa)
Fragment:RESIDUES 1-56,49-160,171-231
Chain B
171–231(61 aa)
Fragment:RESIDUES 1-56,49-160,171-231
|
Not recorded | 5GP GUANOSINE-5'-MONOPHOSPHATE × 2 SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 8;0.1M TRIS PH 8.0, 2.0M AMMONIUM SULPHATE
|
Resolution 2.80 Å R-free 0.278 |
| 3OZF Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with hypoxanthine Deposited 2010-09-24 | Assembly 1 Protein homooligomer Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
1–231(231 aa)
Chain B
1–231(231 aa)
Chain C
1–231(231 aa)
Chain D
1–231(231 aa)
|
Not recorded | HPA HYPOXANTHINE × 4 POP PYROPHOSPHATE 2- × 4 PO4 PHOSPHATE ION × 4 MG MAGNESIUM ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7.4;291 K;200mM sodium citrate, 20% PEG3350, pH 7.4, vapor diffusion, sitting drop, temperature 291K
|
Resolution 1.94 Å R-free 0.237 |
| 3OZG Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with S-SerMe-ImmH phosphonate Deposited 2010-09-24 | Assembly 1 Protein homooligomer Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
1–231(231 aa)
Chain B
1–231(231 aa)
|
Not recorded | SSI [(3S)-4-hydroxy-3-{[(4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}butyl]phosphonic acid × 4 POP PYROPHOSPHATE 2- × 4 MG MAGNESIUM ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7.4;291 K;200mM sodium citrate, 20% PEG3350, pH 7.4, vapor diffusion, sitting drop, temperature 291K
|
Resolution 1.99 Å R-free 0.264 |
| 3OZG Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with S-SerMe-ImmH phosphonate Deposited 2010-09-24 | Assembly 2 Protein homooligomer Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain C
1–231(231 aa)
Chain D
1–231(231 aa)
|
Not recorded | SSI [(3S)-4-hydroxy-3-{[(4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}butyl]phosphonic acid × 4 POP PYROPHOSPHATE 2- × 4 MG MAGNESIUM ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7.4;291 K;200mM sodium citrate, 20% PEG3350, pH 7.4, vapor diffusion, sitting drop, temperature 291K
|
Resolution 1.99 Å R-free 0.264 |
| 7TUX Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with [(3S)-4-Hydroxy-3-[({2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl}methyl)amino]butyl]phosphonic acid Deposited 2022-02-03 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–231(231 aa)
|
Not recorded | YBM [(3S)-3-{[(2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}-4-hydroxybutyl]phosphonic acid × 1 POP PYROPHOSPHATE 2- × 1 MG MAGNESIUM ION × 1 EDO 1,2-ETHANEDIOL × 9 ACY ACETIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;295 K;200 mM Lithium Acetate, 20% PEG3350
|
Resolution 1.62 Å R-free 0.195 |
| 7TUX Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with [(3S)-4-Hydroxy-3-[({2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl}methyl)amino]butyl]phosphonic acid Deposited 2022-02-03 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
1–231(231 aa)
|
Not recorded | YBM [(3S)-3-{[(2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}-4-hydroxybutyl]phosphonic acid × 1 POP PYROPHOSPHATE 2- × 1 MG MAGNESIUM ION × 1 EDO 1,2-ETHANEDIOL × 12 ACY ACETIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;295 K;200 mM Lithium Acetate, 20% PEG3350
|
Resolution 1.62 Å R-free 0.195 |
| 7TUX Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with [(3S)-4-Hydroxy-3-[({2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl}methyl)amino]butyl]phosphonic acid Deposited 2022-02-03 | Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain C
1–231(231 aa)
|
Not recorded | YBM [(3S)-3-{[(2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}-4-hydroxybutyl]phosphonic acid × 1 POP PYROPHOSPHATE 2- × 1 MG MAGNESIUM ION × 1 EDO 1,2-ETHANEDIOL × 10 ACY ACETIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;295 K;200 mM Lithium Acetate, 20% PEG3350
|
Resolution 1.62 Å R-free 0.195 |
| 7TUX Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with [(3S)-4-Hydroxy-3-[({2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl}methyl)amino]butyl]phosphonic acid Deposited 2022-02-03 | Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain D
1–231(231 aa)
|
Not recorded | YBM [(3S)-3-{[(2-amino-4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}-4-hydroxybutyl]phosphonic acid × 1 POP PYROPHOSPHATE 2- × 1 MG MAGNESIUM ION × 1 EDO 1,2-ETHANEDIOL × 5 ACY ACETIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;295 K;200 mM Lithium Acetate, 20% PEG3350
|
Resolution 1.62 Å R-free 0.195 |