Current Protein Identity：P20309
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2CSA Structure of the M3 Muscarinic Acetylcholine Receptor Basolateral Sorting Signal Deposited 2005-05-21 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
271–289（19 aa）
Fragment：THIRD INTRACELLULAR LOOP (Residues:271-289)
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.4；285 K；Pressure ambient
NMR measurement conditions
pH 6.4；278 K；Pressure ambient
NMR measurement conditions
pH 6.4；288 K；Pressure ambient
NMR measurement conditions
pH 6.4；298 K；Pressure ambient
NMR measurement conditions
pH 6.4；308 K；Pressure ambient
NMR measurement conditions
pH 6.4；318 K；Pressure ambient
NMR sample composition
1-2mM M3 peptide, unlabeled, 50mM sodium phosphate buffer, 1mM EDTA, 1mM NaN3, 90% H2O, 10% D20 | 90% H2O, 10% D20
NMR sample composition
1-2mM M3 peptide, unlabeled, 50mM sodium phosphate buffer, 1mM EDTA, 1mM NaN3, 99.9 % D20, 0.1% H20 | 99.9 % D20, 0.1% H20
|
Resolution not provided |
| 8E9W CryoEM structure of miniGq-coupled hM3Dq in complex with DCZ Deposited 2022-08-27 | Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain A
46–283（238 aa）
Chain A
464–590（127 aa）
|
Mutation：Y149C, A239G Mutation：Y149C, A239G | WEC 11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 2.69 Å |
| 8E9Y CryoEM structure of miniGq-coupled hM3Dq in complex with CNO Deposited 2022-08-27 | Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain A
46–283（238 aa）
Chain A
464–590（127 aa）
|
Not recorded | WE9 8-chloro-11-(4-methyl-4-oxo-4lambda~5~-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 2.79 Å |
| 8E9Z CryoEM structure of miniGq-coupled hM3R in complex with Iperoxo Deposited 2022-08-27 | Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain A
46–283（238 aa）
Chain A
464–590（127 aa）
|
Not recorded | IXO 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium × 1 Y01 CHOLESTEROL HEMISUCCINATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 2.69 Å |
| 8EA0 CryoEM structure of miniGq-coupled hM3R in complex with iperoxo (local refinement) Deposited 2022-08-27 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
46–283（238 aa）
Chain A
464–590（127 aa）
|
Not recorded | IXO 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium × 1 Y01 CHOLESTEROL HEMISUCCINATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 2.56 Å |