Current Protein Identity:P27870
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1F5X NMR STRUCTURE OF THE Y174 AUTOINHIBITED DBL HOMOLOGY DOMAIN Deposited 2000-06-18 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
168–375(208 aa)
Fragment:DBL HOMOLOGY DOMAIN
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7;298 K;Ionic strength (raw mmCIF value) 70 mM;Pressure ambient
NMR sample composition
1.4 mM 15N,13C,2H; 20 mM phosphate buffer; 50 mM NaCl; 90% H2O, 10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 1GCP CRYSTAL STRUCTURE OF VAV SH3 DOMAIN Deposited 2000-08-08 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
595–660(66 aa)
Fragment:N-TERMINAL DOMAIN
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8.5;277.2 K;PEG4000, tris(hydroxymethyl)aminomethane, isopropanol, pH 8.5, VAPOR DIFFUSION, SITTING DROP, temperature 277.2K
|
Resolution 2.10 Å R-free 0.253 |
| 1GCP CRYSTAL STRUCTURE OF VAV SH3 DOMAIN Deposited 2000-08-08 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
595–660(66 aa)
Fragment:N-TERMINAL DOMAIN
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8.5;277.2 K;PEG4000, tris(hydroxymethyl)aminomethane, isopropanol, pH 8.5, VAPOR DIFFUSION, SITTING DROP, temperature 277.2K
|
Resolution 2.10 Å R-free 0.253 |
| 1GCP CRYSTAL STRUCTURE OF VAV SH3 DOMAIN Deposited 2000-08-08 | Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain C
595–660(66 aa)
Fragment:N-TERMINAL DOMAIN
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8.5;277.2 K;PEG4000, tris(hydroxymethyl)aminomethane, isopropanol, pH 8.5, VAPOR DIFFUSION, SITTING DROP, temperature 277.2K
|
Resolution 2.10 Å R-free 0.253 |
| 1GCP CRYSTAL STRUCTURE OF VAV SH3 DOMAIN Deposited 2000-08-08 | Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain D
595–660(66 aa)
Fragment:N-TERMINAL DOMAIN
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8.5;277.2 K;PEG4000, tris(hydroxymethyl)aminomethane, isopropanol, pH 8.5, VAPOR DIFFUSION, SITTING DROP, temperature 277.2K
|
Resolution 2.10 Å R-free 0.253 |
| 1GCQ CRYSTAL STRUCTURE OF VAV AND GRB2 SH3 DOMAINS Deposited 2000-08-08 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain C
595–660(66 aa)
Fragment:N-TERMINAL SH3 DOMAIN
|
Not recorded | MRD (4R)-2-METHYLPENTANE-2,4-DIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;293.2 K;2-methyl-2,4-pentanediol, imidazole, magnesium chloride, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 293.2K
|
Resolution 1.68 Å R-free 0.235 |
| 1K1Z Solution structure of N-terminal SH3 domain mutant(P33G) of murine Vav Deposited 2001-09-26 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
583–660(78 aa)
Fragment:N-terminal SH3 domain
|
Mutation:P33G | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.8;298 K;Pressure 1
NMR sample composition
1.5mM protein U-15N,13C;
10mM phosphate buffer K;
10mM DTT-d | 90% H2O/10% D2O
|
Resolution not provided |
| 2KBT Attachment of an NMR-invisible solubility enhancement tag (INSET) using a sortase-mediated protein ligation method Deposited 2008-12-07 | Assembly 1 Insufficient information Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
784–844(61 aa)
Fragment:SH3 2 domain of Proto-oncogene vav,UNP residues 228-282 of Immunoglobulin G-binding protein G
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7;298 K;Ionic strength (raw mmCIF value) 150;Pressure ambient
NMR sample composition
20 mM MES-1, 2 mM DTT-2, 150 mM NaCl-3, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2VRW Critical structural role for the PH and C1 domains of the Vav1 exchange factor Deposited 2008-04-16 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
170–575(406 aa)
Fragment:RESIDUES 170-575
|
Not recorded | ZN ZINC ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 9;100MM BICINE PH9.0 10% PEG 6000
|
Resolution 1.85 Å R-free 0.251 |