Current Protein Identity：P28799
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1G26 THE SOLUTION STRUCTURE OF A WELL-FOLDED PEPTIDE BASED ON THE 31-RESIDUE AMINO-TERMINAL SUBDOMAIN OF HUMAN GRANULIN A Deposited 2000-10-17 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
281–311（31 aa）
Fragment：N-TERMINAL DOMAIN (RESIDUES 1-31)
|
Mutation：D1V, K3H, S9I, Q20P | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 5；288 K；Pressure ambient
NMR measurement conditions
pH 5；298 K；Pressure ambient
NMR sample composition
0.5 mM HGA 1-31 (D1V, K3H, S9I, Q20P); 20 mM sodium acetate-d3, 10% D2O, 90% H2O | 10% D2O, 90% H2O
NMR sample composition
0.5 mM HGA 1-31 (D1V, K3H, S9I, Q20P); 20 mM sodium acetate-d3, 100% D2O | 100% D2O
|
Resolution not provided |
| 2JYE Human Granulin A Deposited 2007-12-13 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
281–337（57 aa）
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.8；298 K；Pressure ambient
NMR measurement conditions
pH 6.8；288 K；Pressure ambient
NMR sample composition
10 mM sodium phosphate, 150 mM sodium chloride, 0.2 mM EDTA, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
10 mM sodium phosphate, 150 mM sodium chloride, 0.2 mM EDTA, 100% D2O | 100% D2O
|
Resolution not provided |
| 2JYT Human Granulin C, isomer 1 Deposited 2007-12-19 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
364–417（54 aa）
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.8；298 K；Pressure ambient
NMR measurement conditions
pH 6.8；288 K；Pressure ambient
NMR sample composition
10 mM sodium phosphate, 150 mM sodium chloride, 0.2 mM EDTA, 0.5-1.0 mM HgrnC1, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
10 mM sodium phosphate, 150 mM sodium chloride, 0.2 mM EDTA, 0.5-1.0 mM HgrnC1, 100% D2O | 100% D2O
|
Resolution not provided |
| 2JYU Human Granulin C, isomer 2 Deposited 2007-12-19 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
364–417（54 aa）
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.8；298 K；Pressure ambient
NMR measurement conditions
pH 6.8；288 K；Pressure ambient
NMR sample composition
10 mM sodium phosphate, 150 mM sodium chloride, 0.2 mM EDTA, 0.5-1.0 mM HgrnC2, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
10 mM sodium phosphate, 150 mM sodium chloride, 0.2 mM EDTA, 0.5-1.0 mM HgrnC2, 100% D2O | 100% D2O
|
Resolution not provided |
| 2JYV Human Granulin F Deposited 2007-12-19 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
123–179（57 aa）
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.8；298 K；Pressure ambient
NMR measurement conditions
pH 6.8；288 K；Pressure ambient
NMR sample composition
10 mM sodium phosphate, 150 mM sodium chloride, 0.2 mM EDTA, 0.5-1.0 mM [U-100% 15N] HgrnF, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
10 mM sodium phosphate, 150 mM sodium chloride, 0.2 mM EDTA, 0.5-1.0 mM [U-100% 15N] HgrnF, 100% D2O | 100% D2O
|
Resolution not provided |
| 6NUG hGRNA4-28_3s Deposited 2019-02-01 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
284–307（24 aa）
Fragment：residues 284-307
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 5；290 K；Pressure 1
NMR sample composition
0.5 mM hGRNA4-28_3s, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 8T8R Sortilin-PGRN peptide complex Deposited 2023-06-23 | Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
578–593（16 aa）
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；293 K；20.00 %w/ PEG 3350, 0.20 M Sodium citrate
|
Resolution 2.87 Å R-free 0.287 |
| 8T8S Sortilin-PGRN peptide complex Deposited 2023-06-23 | Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
578–593（16 aa）
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 7；293 K；0.10 M Tris, 30.00 %w/v PEG 3000, 0.20 M NaCl
|
Resolution 2.99 Å R-free 0.275 |
| 8T8S Sortilin-PGRN peptide complex Deposited 2023-06-23 | Assembly 2 Other combination Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
578–593（16 aa）
|
Not recorded | CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 7；293 K；0.10 M Tris, 30.00 %w/v PEG 3000, 0.20 M NaCl
|
Resolution 2.99 Å R-free 0.275 |