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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P49023 New Search
12PDB entries
23Biological assembly
29chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
2O9V The second SH3 domain from Ponsin in complex with the paxillin proline rich region Deposited 2006-12-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 45–54（10 aa） Fragment：Proline rich region
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；292 K；0.2M Sodium Acetate, 0.1M Sodium Cacodylate, 30% (w/v) PEG 8000, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 292K
Resolution 1.63 Å R-free 0.177
2VZD Crystal structure of the C-terminal calponin homology domain of alpha parvin in complex with paxillin LD1 motif Deposited 2008-07-31 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 1–20（20 aa） Fragment：PAXILLIN LD1 MOTIF, RESIDUES 1-20
Not recorded PGE TRIETHYLENE GLYCOL × 2 PG4 TETRAETHYLENE GLYCOL × 1 GOL GLYCEROL × 2 EDO 1,2-ETHANEDIOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；20% (W/V) PEG 10000, 0.1M HEPES PH 7.5
Resolution 2.10 Å R-free 0.255
2VZD Crystal structure of the C-terminal calponin homology domain of alpha parvin in complex with paxillin LD1 motif Deposited 2008-07-31 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain D 1–20（20 aa） Fragment：PAXILLIN LD1 MOTIF, RESIDUES 1-20
Not recorded PG4 TETRAETHYLENE GLYCOL × 1 GOL GLYCEROL × 1 EDO 1,2-ETHANEDIOL × 5 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；20% (W/V) PEG 10000, 0.1M HEPES PH 7.5
Resolution 2.10 Å R-free 0.255
2VZG Crystal structure of the C-terminal calponin homology domain of alpha- parvin in complex with paxillin LD2 motif Deposited 2008-08-01 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 8–27（20 aa） Fragment：PAXILLIN LD1 MOTIF, RESIDUES 141-160
Not recorded PG4 TETRAETHYLENE GLYCOL × 1 PGE TRIETHYLENE GLYCOL × 1 EDO 1,2-ETHANEDIOL × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.5；286 K；40% (W/V) PEG200, 0.1 M CITRATE PH 4.5
Resolution 1.80 Å R-free 0.221
2VZI Crystal structure of the C-terminal calponin homology domain of alpha- parvin in complex with paxillin LD4 motif Deposited 2008-08-01 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 262–277（16 aa） Fragment：;PAXILLIN LD4 MOTIF, RESIDUES 262-277 AND 312-315 OF PAXILLIN ISOFORM BETA,PAXILLIN LD4 MOTIF, RESIDUES 262-277 AND 312-315 OF PAXILLIN ISOFORM BETA ;
Chain A 312–315（4 aa） Fragment：;PAXILLIN LD4 MOTIF, RESIDUES 262-277 AND 312-315 OF PAXILLIN ISOFORM BETA,PAXILLIN LD4 MOTIF, RESIDUES 262-277 AND 312-315 OF PAXILLIN ISOFORM BETA ;
Not recorded PG4 TETRAETHYLENE GLYCOL × 1 EDO 1,2-ETHANEDIOL × 2 PGE TRIETHYLENE GLYCOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.2；286 K；40%(W/V) PEG 300, 0.1M CITRATE PH 5.2
Resolution 2.20 Å R-free 0.260
3GM1 Crystal Structure of the Focal Adhesion Targeting (FAT) Domain of Pyk2 in Complex with Paxillin LD4 Motif-Derived Peptides Deposited 2009-03-12 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain E 262–274（13 aa） Fragment：Paxillin LD4 Motif, UNP residues 262-274
Chain F 262–274（13 aa） Fragment：Paxillin LD4 Motif, UNP residues 262-274
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.3；298 K；4.1 M NaCl, 100 mM HEPES, 5% glycerol, pH 6.3, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.95 Å R-free 0.290
3GM1 Crystal Structure of the Focal Adhesion Targeting (FAT) Domain of Pyk2 in Complex with Paxillin LD4 Motif-Derived Peptides Deposited 2009-03-12 Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain C 262–274（13 aa） Fragment：Paxillin LD4 Motif, UNP residues 262-274
Chain D 262–274（13 aa） Fragment：Paxillin LD4 Motif, UNP residues 262-274
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.3；298 K；4.1 M NaCl, 100 mM HEPES, 5% glycerol, pH 6.3, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.95 Å R-free 0.290
3PY7 Crystal structure of full-length Bovine Papillomavirus oncoprotein E6 in complex with LD1 motif of paxillin at 2.3A resolution Deposited 2010-12-12 Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–10（10 aa）
Mutation：D108A,K109A,K265A,E385A,K388A,D389A (maltose-binding periplasmic protein) ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；290 K；1.6 M ammonium sulfate, 2% PEG2000 MME 0.1 M HEPES sodium, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 290K
Resolution 2.29 Å R-free 0.225
3U3F Structural basis for the interaction of Pyk2 PAT domain with paxillin LD motifs Deposited 2011-10-05 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain E 261–277（17 aa） Fragment：unp residues 261-277
Chain I 261–277（17 aa） Fragment：unp residues 261-277
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.3；291.2 K；The 4 ul drop contained 2 ul protein-LD4 peptide mixture (20mM Mes, pH6.2, 1mM protein, 2 mM peptide) and 2 ul ML (100 mM MES pH6.3, 4.2 M NaCl, 2%(v/v) glycerol., VAPOR DIFFUSION, SITTING DROP, temperature 291.2K
Resolution 3.10 Å R-free 0.266
3U3F Structural basis for the interaction of Pyk2 PAT domain with paxillin LD motifs Deposited 2011-10-05 Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain F 261–277（17 aa） Fragment：unp residues 261-277
Chain J 261–277（17 aa） Fragment：unp residues 261-277
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.3；291.2 K；The 4 ul drop contained 2 ul protein-LD4 peptide mixture (20mM Mes, pH6.2, 1mM protein, 2 mM peptide) and 2 ul ML (100 mM MES pH6.3, 4.2 M NaCl, 2%(v/v) glycerol., VAPOR DIFFUSION, SITTING DROP, temperature 291.2K
Resolution 3.10 Å R-free 0.266
3U3F Structural basis for the interaction of Pyk2 PAT domain with paxillin LD motifs Deposited 2011-10-05 Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain G 261–277（17 aa） Fragment：unp residues 261-277
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.3；291.2 K；The 4 ul drop contained 2 ul protein-LD4 peptide mixture (20mM Mes, pH6.2, 1mM protein, 2 mM peptide) and 2 ul ML (100 mM MES pH6.3, 4.2 M NaCl, 2%(v/v) glycerol., VAPOR DIFFUSION, SITTING DROP, temperature 291.2K
Resolution 3.10 Å R-free 0.266
3U3F Structural basis for the interaction of Pyk2 PAT domain with paxillin LD motifs Deposited 2011-10-05 Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain H 261–277（17 aa） Fragment：unp residues 261-277
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.3；291.2 K；The 4 ul drop contained 2 ul protein-LD4 peptide mixture (20mM Mes, pH6.2, 1mM protein, 2 mM peptide) and 2 ul ML (100 mM MES pH6.3, 4.2 M NaCl, 2%(v/v) glycerol., VAPOR DIFFUSION, SITTING DROP, temperature 291.2K
Resolution 3.10 Å R-free 0.266
4EDN Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif Deposited 2012-03-27 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain K 1–20（20 aa） Fragment：LD1 motif
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；298 K；2.1M Ammonium sulfate, 0.01M Tris, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.90 Å R-free 0.265
4EDN Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif Deposited 2012-03-27 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain L 1–20（20 aa） Fragment：LD1 motif
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；298 K；2.1M Ammonium sulfate, 0.01M Tris, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.90 Å R-free 0.265
4EDN Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif Deposited 2012-03-27 Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain M 1–20（20 aa） Fragment：LD1 motif
Non-standard monomer：Yes (specific site not provided by mmCIF) SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；298 K；2.1M Ammonium sulfate, 0.01M Tris, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.90 Å R-free 0.265
4EDN Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif Deposited 2012-03-27 Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain N 1–20（20 aa） Fragment：LD1 motif
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；298 K；2.1M Ammonium sulfate, 0.01M Tris, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.90 Å R-free 0.265
4EDN Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif Deposited 2012-03-27 Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain O 1–20（20 aa） Fragment：LD1 motif
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；298 K；2.1M Ammonium sulfate, 0.01M Tris, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.90 Å R-free 0.265
4EDN Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif Deposited 2012-03-27 Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain P 1–20（20 aa） Fragment：LD1 motif
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；298 K；2.1M Ammonium sulfate, 0.01M Tris, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.90 Å R-free 0.265
4EDN Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif Deposited 2012-03-27 Assembly 7 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain Q 1–20（20 aa） Fragment：LD1 motif
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；298 K；2.1M Ammonium sulfate, 0.01M Tris, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.90 Å R-free 0.265
6U4M Solution structure of paxillin LIM4 Deposited 2019-08-26 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 527–591（65 aa） Fragment：LIM4 domain residues 527-591
Not recorded ZN ZINC ION × 2 SOLUTION NMR
NMR measurement conditions pH 6.8；298 K；Ionic strength (raw mmCIF value) 50mM NaCl；Pressure ambient
NMR sample composition 1.45 mM [U-13C; U-15N] Paxillin LIM4, 95% H2O/5% D2O | 95% H2O/5% D2O
Resolution not provided
6U4N Solution structure of paxillin LIM4 in complex with kindlin-2 F0 Deposited 2019-08-26 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 527–591（65 aa） Fragment：LIM4 domain residues 527-591
Not recorded ZN ZINC ION × 2 SOLUTION NMR
NMR measurement conditions pH 6.8；298 K；Ionic strength (raw mmCIF value) 50 mM NaCl；Pressure ambient
NMR measurement conditions pH 6.8；298 K；Ionic strength (raw mmCIF value) 50 mM NaCl；Pressure ambient
NMR sample composition 0.55 mM U-15N, U-13C paxillin LIM4, 0.89 mM kindlin-2 F0, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition 0.54 mM U-15N, U-13C kindlin-2 F0, 0.85 mM paxillin LIM4, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition 0.55 mM U-15N, U-13C paxillin LIM4, 0.89 mM kindlin-2 F0, 99.8% D2O | 99.8% D2O
NMR sample composition 0.54 mM U-15N, U-13C kindlin-2 F0, 0.85 mM paxillin LIM4, 99.8% D2O | 99.8% D2O
Resolution not provided
7QB0 Solution structure of paxillin LIM2/3 Deposited 2021-11-17 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 380–499（120 aa）
Not recorded ZN ZINC ION × 4 SOLUTION NMR
NMR measurement conditions pH 7.5；298.15 K；Ionic strength (raw mmCIF value) 150mM NaCl；Pressure 1
NMR sample composition 500 uM [U-13C; U-15N] Paxillin LIM2/3, 150 mM sodium chloride, 50 mM sodium phosphate, 4 mM sodium azide, 1 mM DTT, 0.1 mM DSS, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition 500 uM [U-13C; U-15N] Paxillin LIM2/3, 150 mM sodium chloride, 50 mM sodium phosphate, 4 mM sodium azide, 1 mM DTT, 0.1 mM DSS, 100% D2O | 100% D2O
Resolution not provided
9QWO Vinculin tail bound to paxillin LD2 Deposited 2025-04-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain E 140–158（19 aa）
Chain F 140–158（19 aa）
Not recorded SO4 SULFATE ION × 8 ACT ACETATE ION × 10 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；295 K；1.26 M (NH4)2SO4, 0.2 M NaCl, 0.1 M Na Acetate pH4.5
Resolution 2.54 Å R-free 0.259

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.