Current Protein Identity：P54252
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1YZB Solution structure of the Josephin domain of Ataxin-3 Deposited 2005-02-28 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–182（182 aa）
Fragment：N-terminal domain of Ataxin-3
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.5；298 K；Ionic strength (raw mmCIF value) 20mM sodium phosphate；Pressure ambient
NMR sample composition
0.4mM of Josephin 15N, 13C; 20mM sodium phosphate buffer (pH 6.5); 90% H2O, 10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2AGA De-ubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain Deposited 2005-07-26 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–185（185 aa）
Fragment：Josephin domain
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.4；298 K；Ionic strength (raw mmCIF value) 20 mM KPO4；Pressure 1
NMR sample composition
2mM Josephin domain U-15N,13C; 20mM phosphate buffer pH 6.4; 90% H2O, 10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2DOS Structural basis for the recognition of Lys48-linked polyubiquitin chain by the Josephin domain of ataxin-3, a putative deubiquitinating enzyme Deposited 2006-05-03 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–171（171 aa）
Fragment：Josephin domain
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；303 K；Ionic strength (raw mmCIF value) 10mM Sodium phosphate buffer；Pressure 1
NMR sample composition
1.2mM Josephin domain U-15N,13C; 10mM Sodium phosphate buffer; 90% H2O, 10% D2O | 90% H2O/10% D2O
NMR sample composition
1.2mM Josephin domain U-15N,13C; 10mM Sodium phosphate buffer; 99% D2O | 99% D2O
|
Resolution not provided |
| 2JRI Solution structure of the Josephin domain of Ataxin-3 in complex with ubiquitin molecule. Deposited 2007-06-27 | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count |
Chain A
1–182（182 aa）
Fragment：N-terminal domain of ataxin-3 sequence database residues 1-182
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.5；298 K；Ionic strength (raw mmCIF value) 0.01；Pressure ambient
NMR sample composition
0.1 - 0.3 mM [U-15N] protein, 0.1 -0.3 mM [U-13C; U-15N] protein, 0.1-0.3 mM protein, 0.1-0.3 mM [U-13C; U-15N; U-2H] protein, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2KLZ Solution Structure of the Tandem UIM Domain of Ataxin-3 Complexed with Ubiquitin Deposited 2009-07-12 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
222–263（42 aa）
Fragment：UIM1 and UIM 2 domain, UNP residues 222-263
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.5；298 K；Pressure ambient
NMR sample composition
1 mM [U-100% 15N] protein-1, 20 mM sodium phosphate-2, 100 mM sodium chloride-3, 0.02 % sodium azide-4, 4 mM ubiquitin-5, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
1 mM [U-100% 13C; U-100% 15N] protein-6, 20 mM sodium phosphate-7, 100 mM sodium chloride-8, 0.02 % sodium azide-9, 4 mM ubiquitin-10, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 4WTH Ataxin-3 Carboxy Terminal Region - Crystal C2 (triclinic) Deposited 2014-10-30 | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
278–324（47 aa）
Fragment：MBP residues 27-392 (UNP) + Ataxin-3 C-terminal region (UNP residues 278-324)
|
Not recorded | ZN ZINC ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；24% PEG5000 MME, 0.9 M sodium acetate, 0.06 M imidazole, pH 8.0, 0.1 M zinc acetate
|
Resolution 2.25 Å R-free 0.250 |
| 4WTH Ataxin-3 Carboxy Terminal Region - Crystal C2 (triclinic) Deposited 2014-10-30 | Assembly 2 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
278–324（47 aa）
Fragment：MBP residues 27-392 (UNP) + Ataxin-3 C-terminal region (UNP residues 278-324)
|
Not recorded | ZN ZINC ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；24% PEG5000 MME, 0.9 M sodium acetate, 0.06 M imidazole, pH 8.0, 0.1 M zinc acetate
|
Resolution 2.25 Å R-free 0.250 |
| 4YS9 Ataxin-3 Carboxy-Terminal Region - Crystal C1 (tetragonal) Deposited 2015-03-16 | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
278–324（47 aa）
Fragment：MBP residues 27-392 (UNP) + Ataxin-3 C-terminal region (UNP residues 278-324)
|
Not recorded | ZN ZINC ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；278 K；25% PEG5000 MME, 1.0 M sodium acetate, 0.1 M imidazole, pH 8.0, 0.1 M zinc acetate
|
Resolution 2.00 Å R-free 0.223 |