← Back to search

Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P54278 New Search
9PDB entries
13Biological assembly
16chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1EA6 N-terminal 40kDa fragment of NhPMS2 complexed with ADP Deposited 2001-07-10 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–364（364 aa） Fragment：N-TERMINAL 40KDA, RESIDUES 1-364
Not recorded MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.2；2-2.4 M NA/K PHOSPHATE (PH 6.2) 0.2 M LICL
Resolution 2.70 Å R-free 0.262
1EA6 N-terminal 40kDa fragment of NhPMS2 complexed with ADP Deposited 2001-07-10 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 1–364（364 aa） Fragment：N-TERMINAL 40KDA, RESIDUES 1-364
Not recorded MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.2；2-2.4 M NA/K PHOSPHATE (PH 6.2) 0.2 M LICL
Resolution 2.70 Å R-free 0.262
1H7S N-terminal 40kDa fragment of human PMS2 Deposited 2001-07-10 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–365（365 aa） Fragment：N-TERMINAL 40 KDA FRAGMENT
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.2；2-2.4 M NA/K PHOSPHATE (PH 6.2) 0.2 M LICL
Resolution 1.95 Å R-free 0.243
1H7S N-terminal 40kDa fragment of human PMS2 Deposited 2001-07-10 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 1–365（365 aa） Fragment：N-TERMINAL 40 KDA FRAGMENT
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.2；2-2.4 M NA/K PHOSPHATE (PH 6.2) 0.2 M LICL
Resolution 1.95 Å R-free 0.243
1H7U hPMS2-ATPgS Deposited 2001-07-10 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–365（365 aa） Fragment：GHL ATPASE, RESIDUES 1-365
Not recorded MG MAGNESIUM ION × 1 AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.2；2-2.4 M NA/K PHOSPHATE (PH=6.2) 0.2 M LICL, pH 6.20
Resolution 2.70 Å R-free 0.270
1H7U hPMS2-ATPgS Deposited 2001-07-10 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 1–365（365 aa） Fragment：GHL ATPASE, RESIDUES 1-365
Not recorded MG MAGNESIUM ION × 1 AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.2；2-2.4 M NA/K PHOSPHATE (PH=6.2) 0.2 M LICL, pH 6.20
Resolution 2.70 Å R-free 0.270
5U5R Crystal Structure and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a PMS2 NLS Peptide Deposited 2016-12-07 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 573–583（11 aa）
Not recorded DTT 2,3-DIHYDROXY-1,4-DITHIOBUTANE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.600-0.625 M sodium citrate (pH 6) and 10 mM DTT
Resolution 2.10 Å R-free 0.207
6MFQ Crystal structure of a PMS2 variant Deposited 2018-09-11 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–365（365 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；289.15 K；Crystals were obtained in conditions containing 4% tacsimate pH 5 (v/v) and 25% PEG 3350 (w/v). The concentrated PMS2 G207E protein (7 mg/mL) was combined with 0.1ul of an additive (0.1 M calcium chloride dehydrate) prior to the addition of crystallization reagent in a 1:1 ratio.
Resolution 2.60 Å R-free 0.232
6MFQ Crystal structure of a PMS2 variant Deposited 2018-09-11 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 1–365（365 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；289.15 K；Crystals were obtained in conditions containing 4% tacsimate pH 5 (v/v) and 25% PEG 3350 (w/v). The concentrated PMS2 G207E protein (7 mg/mL) was combined with 0.1ul of an additive (0.1 M calcium chloride dehydrate) prior to the addition of crystallization reagent in a 1:1 ratio.
Resolution 2.60 Å R-free 0.232
7RCB Crystal Structure of a PMS2 VUS Deposited 2021-07-07 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–365（365 aa）
Chain B 1–365（365 aa）
Mutation：N335S Mutation：N335S No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.8；289.15 K；1:1 7.5 mg/mL protein with 8% v/v Tacsimate, pH 5.8, 25% w/v PEG3350
Resolution 2.00 Å R-free 0.198
7RCI Crystal Structure of a PMS2 VUS with Substrate Deposited 2021-07-07 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–365（365 aa）
Chain B 1–365（365 aa）
Mutation：N335S Mutation：N335S ATP ADENOSINE-5'-TRIPHOSPHATE × 2 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.8；289.15 K；1:1 7.5 mg/mL protein with 8% v/v Tacsimate, pH 5.8, 25% w/v PEG3350
Resolution 2.12 Å R-free 0.248
7RCK Crystal Structure of PMS2 with Substrate Deposited 2021-07-07 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–365（365 aa）
Chain B 1–365（365 aa）
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 2 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.8；289.15 K；1:1 7.5 mg/mL protein with 8% v/v Tacsimate, pH 5.8, 25% w/v PEG3350
Resolution 2.04 Å R-free 0.234
9S89 N-terminal 40kDa fragment of human PMS2 with covalent ligand NP1867 Deposited 2025-08-05 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–365（365 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.00 Å R-free 0.229

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.